Anticoccidial methods and feedstuffs

ABSTRACT

The present invention is directed to anticoccidial methods, animal feed premixes, and animal feeds, employing a specified o-phenylenediamine or benzimidazole. The present invention is also directed to anticoccidial methods, animal feed premixes, and animal feeds employing two active agents. In such combined therapy, a first substance is a polyether antibiotic, and the second substance is a designated o-phenylenediamine, benzimidazole, or benzimidazoline.

This application is a continuation of application Ser. No. 08/230,959 filed Apr. 21, 1994 U.S. Pat. No. 5,502,040, which is a division of application Ser. No. 08/037,800, filed Mar. 26, 1993, and issued Jul. 19, 1994 as U.S. Pat. No. 5,331,003.

BRIEF SUMMARY OF THE INVENTION

Coccidiosis is a protozoan disease of fowl and other animals. Uncontrolled, it is a devastating disease. Chemotherapeutics are known, such as the polyethers monensin and narasin, sold under the trademarks Coban® and Monteban®, respectively. However, them are various problems. Some chemotherapeutics cause undesirable side effects. Others, especially if used recurringly in a facility, lead to the development of reduced sensitivity or resistance to a particular chemotherapeutic or entire class of chemotherapeutics. For this reason, combinations are employed, such as the combination of narasin and nicarbazin, sold under the trademark Maxiban®. Also, "rotation" and "shuttle" regimens are used, in which different anticoccidial regimens are employed from one growout to the next, and during a growout. However, even with all of these available techniques, them is still a continuing need to discover new chemotherapeutic techniques for the control of coccidiosis.

It has now been discovered that certain phenylenediamines and benzimidazoles, more fully defined below, are efficacious against coccidiosis. These compounds can be employed to treat and/or prevent coccidiosis in fowl. They may be employed alone or, in a preferred embodiment, they are employed in combination with a polyether. In an especially preferred embodiment, the present combination therapy is used to prevent or treat coccidiosis attributable to a polyether-insensitive strain of Eimeria. The topic of drug insensitivity is well reviewed in

Jeffers, T. K. Coccidia and intestinal coccidiomorphs, Vth International Coccidiosis Conference, Tours (France), 17-20 October 1989. Ed. INRA Publ., 1989 (Les Colloques de I'INRA, no. 49), pages 295-308. Anticoccidial drug resistance: a review with emphasis on the polyether ionophores.

DETAILED DESCRIPTION OF THE INVENTION

The present invention is directed to a method of preventing or treating coccidiosis in a fowl which comprises administering to the fowl an effective amount of an active agent selected from compounds of the formulae ##STR1## wherein

R¹ represents bromo or chloro,

m represents an integer of 0 or 1 and n represents an integer of from 0 to 3, with the sum of m and n being an integer of from 1 to 3;

R² represents difluoroacetyl, chlorodifluoroacetyl, 2,2,3,3-tetrafluoropropionyl, or a perfluoroalkanoyl of from C₂ to C₄ ;

R³ represents H, trichloroacetyl, or an independently selected R² ;

R⁴ represents H, OH, OCH₃, or a group hydrolyzable to a foregoing R⁴ moiety; and

R⁵ represents difluoromethyl, chlorodifluoromethyl, 1,1,2,2-tetrafluoroethyl, or a perfluoroalkyl of C₁ -C₃ ; or a physiologically acceptable salt of a Formula II compound.

The present invention is also directed to animal feed premixes and final animal feeds comprising an active agent as defined above.

Further, the invention is directed to anticoccidial methods comprising administering both an active agent as defined above, or a benzimidazoline as defined below, as well as a polyether antibiotic. Animal feed premixes and final animal feeds comprising both (1) a phenylenediamine, benzimidazole, or benzimidazoline, and (2) a polyether, are another aspect of the present invention. This combined therapy has unexpectedly been found to provide excellent control of coccidiosis attributable to polyether-insensitive strains.

The benzimidazoline compounds to be employed in this embodiment are of the formula ##STR2## wherein R¹, m, n, and R⁵ have the same meanings set forth above; and R⁶ represents sodium, potassium, lithium, silver, calcium, ammonium, or substituted ammonium derived from an organic amine which is as basic as, or more basic than, ammonia.

The compounds of Formula I, II, and III, are prepared in known procedures, and a large number of specific compounds are taught in the literature. The following U.S. Pat. Nos.

Formula I: 3,557,211 3,907,892 3,989,840

Formula II: 3,980,784

Formula III: 4,265,901

teach the synthesis of many of the compounds to be employed in the present invention, and are hereby incorporated by reference. Several review articles exist and further illustrate the synthesis of compounds to be employed in the present invention:

Chem. Heterocycl. Compd. 40, #1 (1981), pages 1-285

J. Fluoro. Chem. 56, #1 (1992), pages 1-27

Prog. Drug Res. 27 (1983), pages 85-161

Chem. Rev. 74, #3 (1974), pages 279-314.

These also are hereby incorporated by reference.

Compounds of Formula I which can be employed in the present invention include the following:

    __________________________________________________________________________     Example #                                                                              Name                                                                   __________________________________________________________________________      1      3-nitro-5-(trifluoromethyl)-N.sup.1 -(difluoroacetyl)-o-                       phenylenediamine                                                        2      3-nitro-5-chloro-N.sup.1,N.sup.2 -bis(2,2,3,3-tetrafluoropropionyl             )-o-                                                                           phenylenediamine                                                        3      3-nitro-5-chloro-N.sup.1 -(2,2,3,3-tetrafluoropropionyl)-o-                    phenylenediamine                                                        4      3-nitro-5-(trifluoromethyl)-N.sup.1,N.sup.2 -bis(2,2,3,3-                      tetrafluoropropionyl)-o-phenylenediamine                                5      3-nitro-5-(trifluoromethyl)-N.sup.1 -(2,2,3,3-tetrafluoropropionyl             )-o-                                                                           phenylenediamine                                                        6      3-nitro-5-(trifluoromethyl)-N.sup.1 -(2-(trifluoromethyl)-2,3,3,3-             .                                                                              tetrafluoropropionyl)-o-phenylenediamine                                7      3-nitro-5-(trifluoromethyl)-N.sup.1,N.sup.2 -bis(2-(trifluoromethy             l)-2,3,3,3-                                                                    tetrafluoropropionyl)-o-phenylenediamine                                8      5-nitro-3-(trifluoromethyl)-N.sup.1 -(perfluoropropionyl)-o-                   phenylenediamine                                                        9      3-nitro-5-(trifluoromethyl)-N.sup.1 -(perfluoro-n-butyryl)-o-                  phenylenediamine                                                       10      5-nitro-3-(trifluoromethyl)-N.sup.1 -(trifluoroacetyl)-o-                      phenylenediamine                                                       11      3-nitro-5-chloro-N.sup.1,N.sup.2 -bis(trifluoroacetyl)-o-phenylene             diamine                                                                12      3-nitro-5-(trifluoromethyl)-N.sup.1,N.sup.2 -bis(trifluoroacetyl)-             o-                                                                             phenylenediamine                                                       13      3-nitro-5-chloro-N.sup.1 -(trifluoroacetyl)-o-phenylenediamine         14      3-nitro-5-(trifluoromethyl)-N.sup.1 -(perfluoropropionyl)-o-                   phenylenediamine                                                       15      3-nitro-5-(trifluoromethyl)-N.sup.1 -(perfluoropropionyl)-N.sup.2              -                                                                              (trifluoroacetyl)-o-phenylenediamine                                   16      3-nitro-5-(trifluoromethyl)-N.sup.1 -(trifluoroacetyl)-o-                      phenylenediamine                                                       17      5-nitro-3-trifluoromethyl)-N.sup.1 -(1,1,2,2-tetrafluoropropionyl)             -o-                                                                            phenylenediamine                                                       18      6-nitro-4-(trifluoromethyl)-N.sup.1 -(trifluoroacetyl)-N.sup.2 -               (trichloroacetyl)-o-phenylenediamine                                   19      6-nitro-4-(trifluoromethyl)-N.sup.1 -(perfluoropropionyl)-N.sup.2              -                                                                              (trichloroacetyl)-o-phenylenediamine                                   20      3-nitro-5-(trifluoromethyl)-N.sup.1 -(perfluoropropionyl)-N.sup.2              -                                                                              (trichloroacetyl)-o-phenylenediamine                                   __________________________________________________________________________

Compounds of Formula II which can be employed in the present invention include the following:

    __________________________________________________________________________     Example #                                                                              Name                                                                   __________________________________________________________________________     21      5-nitro-2,6-bis(trifluoromethyl)benzimidazole                          22      4-nitro-6-(trifluoromethyl)-2-(perfluoroethyl)benzimidazole            23      4-nitro-2,6-bis(trifluoromethyl)benzimidazole                          24      6-nitro-5-chloro-2-(trifluoromethyl)benzimidazole                      25      4-nitro-6-chloro-2-(trifluoromethyl)benzimidazole                      26      4-nitro-6-(trifluoromethyl)-2-(difluoromethyl)benzimidazole            27      5-nitro-4-chloro-2-(trifluoromethyl)benzimidazole                      28      7-nitro-4-chloro-2-(trifluoromethyl)benzimidazole                      29      4-nitro-2,6-bis(trifluoromethyl)benzimidazole sodium salt              30      6-nitro-4-chloro-2-(trifluoromethyl)benzimidazole                      31      4-nitro-5-chloro-2-(trifluoromethyl)benzimidazole                      32      7-nitro-4,5-dichloro-2-(trifluoromethyl)benzimidazole                  33      4-nitro-5,6-dichloro-2-(trifluoromethyl)benzimidazole                  34      4-nitro-5,6-dichloro-2-(perfluoroethyl)benzimidazole                   35      4-nitro-7-bromo-2,6-bis(trifluoromethyl)benzimidazole                  36      4-nitro-6-(trifluoromethyl)-2-                                                 (chlorodifluoromethyl)benzimidazole                                    37      4-nitro-2,6-bis(trifluoromethyl)-7-chlorobanzimidazole                 38      6-nitro-2,4-bis(trifluoromethyl)benzimidazole                          39      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole                                         40      7-nitro-5-chloro-2-(perfluoro-n-propyl)benzimidazole                   41      7-nitro-5-(trifluoromethyl)-2-(1-(trifluoromethyl)-2,2,3,3-                    tetrafluoroethyl)benzimidazole                                         42      7-nitro-5-chloro-2-(2,2,3,3-tetrafluoromethyl)benzimidazole            43      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole, salt with tri-n-butylamine             44      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole, salt with tribenzylamine               45      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole, salt with decylamine                   46      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole, salt with phenethylamine               47      4-nitro--6-(trifluoromethyl)-2-(2,2,3,3-                                       tetrafluorethyl)benzimidazole, salt with di-n-hexylamine               48      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole, salt with tri-n-propylamine            49      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole, salt with dodecylamine                 50      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole, salt with triethylamine                51      4-nitro-6-(trifluoromethyl)-2-(perfluoroethyl)benzimidazole,                   sodium salt                                                            52      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole, tetra-n-heptylammonium salt            53      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluorethyl)benzimidazole, tetra-n-propylammonium salt             55      4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                                        tetrafluoroethyl)benzimidazole, benzyltrimethylammonium salt           56      1-hydroxy-4-nitro-2,6-bis(trifluoromethyl)benzimidazole                57      1-hydroxy-4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                              tetrafluorethyl)benzimidazole                                          58      1-hydroxy-4-nitro-6-(trifluoromethyl)-2-                                       (chlorodifluoromethy)benzimidazole                                     59      allyl 4-nitro-2,6-bis(trifluoromethyl)-1-                                      benzimidazolecarboxylate                                               60      4-nitrophenyl 4-nitro-2,6-bis(trifluoromethyl)-1-                              benzimidazolecarboxylate                                               61      4-nitro-N,N-di(n-propyl)-2,6-bis(trifluoromethyl)thio-1-                       benzimidazolecarboxamide                                               62      7-nitro-N,N-di(n-propyl)-2,5-bis(trifluoromethyl)thio-1-                       benzimidazolecarboxamide                                               63      7-nitro-1-(piperidinothionocarbonyl)-2,5-                                      bis(trifluoromethyl)benzimidazole                                      64      4-nitro-1-(piperidinothionocarbonyl)-2,6-                                      bis(trifluoromethyl)benzimidazole                                      65      N-ethyl-4-nitro-2,6-bis(trifluoromethyl)benzimidazole-1-                       thiocarboxanilide                                                      66      N-ethyl-7-nitro-2,5-bis(trifluoromethyl)benzimidazole-1-                       thiocarboxanilide                                                      67      ethyl 4-nitro-2,6-bis(trifluoromethyl)-1-                                      benzimidazolecarboxylate                                               68      phenyl 4-nitro-2,6-bis(trifluoromethyl)-1-                                     benzimidazolecarboxylate                                               69      phenyl 7-nitro-2,5-bis(trifluoromethyl)-1-                                     benzimidazolecarboxylate                                               70      N,N-diethyl-4-nitro-2,6-bis(trifluoromethyl)thio-1-                            benzimidazolecarboxamide                                               71      1-acetyl-7-nitro-2,5-bis(trifluoromethyl)benzimidazole                 72      1-acetyl-4-nitro-2,6-bis(trifluoromethyl)benzimidazole                 73      1-hexanoyl-7-nitro-2,5-bis(triflouromethyl)benzimidazole               74      1-hexanoyl-4-nitro-2,6-bis(trifluoromethyl)benzimidazole               75      2,6-bis(trifluoromethy)-4-nitro-1-                                             (phenylsulfonyl)benzimidazole                                          76      1-(p-anisoyl)-4-nitro-2,6-bis(trifluoromethyl)benzimidazole            77      1-methoxy-4-nitro-2,6-bis(trifluoromethyl)benzimidazole                78      n-hexyl 4-nitro-2,6-bis(trifluoromethyl)-1-                                    benzimidazolecarboxylate                                               79      isopropyl 4-nitro-2,6-bis(trifluoromethyl)-1-                                  benzimidazolecarboxylate                                               80      1-benzoyl-4-nitro-2,6-bis(trifluoromethyl)benzimidazole                81      1-(4-chlorobenzoyl)-4-nitro-2,6-                                               bis(trifluoromethyl)benzimidazole                                      82      N,N-dimethyl-4-nitro-2,6-bis(trifluoromethyl)thio-1-                           benzimidazolecarboxamide                                               83      N,N-dimethyl-7-nitro-2,5-bis(trifluoromethyl)thio-1-                           benzimidazolecarboxamide                                               84      4-nitro-1-(4-nitrobenzoyl)2,6-bis(trifluoromethyl)benzimidazole        85      benzyl 2,6-bis(trifluoromethyl)-4-nitro-1-                                     benzimidazolecarboxylate                                               86      benzyl 2,5-bis(trifluoromethyl)-7-nitro-1-                                     benzimidazolecarboxylate                                               87      methyl 4-nitro-2,6-bis(trifluoromethyl)-1-                                     benzimidazolecarboxylate                                               88      methyl 7-nitro-2,5-bis(trifluoromethyl)-1-                                     benzimidazolecarboxylate                                               89      n-butyl 4-nitro-2,6-bis(trifluoromethyl)benzimidazole-1-                       carboxylate                                                            90      isopropyl 2-(chlorodifluoromethyl)-4-nitro-6-(trifluoromethyl)-1-              benzimidazolecarboxylate                                               91      4-nir\tro-2,6-bis(trifluoromethyl)-1-benzimidazolyl                            methylcarbamate                                                        92      phenyl 2-(chlorodifluoromethyl)-4-nitro-6-(trifluoromethyl)-1-                 benzimidazolecarboxylate                                               93      benzyl 4-nitro-2-(1,1,2,2-tetrafluoroethyl)-6-(trifluoromethyl)-1-             benzimidazolecarboxylate                                               94      1-methoxy-4-nitro-2-(1,1,2,2-tetrafluoroethyl)-6-                              (trifluoromethyl)benzimidazole                                         95      2-ethylhexyl 4-nitro-2-(1,1,2,2-tetrafluoroethyl)-6-                           (trifluoromethyl)-1-benzimidazolecarboxylate                           96      octyl 7-nitro-2-(1,1,2,2-tetrafluoroethyl)-5-(trifluoromethyl)-1-              benzimidazolecarboxylate                                               97      octyl 4-nitro-2-(1,1,2,2-tetrafluoroethyl)-6-(trifluoromethyl)-1-              benzimidazolecarboxylate                                               98      ethyl 4-nitro-2-(1,1,2,2-tetrafluoroethyl)-6-(trifluoromethyl)-1-              benzimidazolecarboxylate                                               99      isopropy 4-nitro-2-(1,1,2,2-tetrafluoroethyl)-6-(trifluoromethyl)-             1-benzimidazolecarboxylate                                             100     1-(phenoxycarbonyloxy)-2-(chlorodifluoromethyl)-4-nitro-6-                     (trifluoromethyl)benzimidazole                                         101     1-methoxy-2-(chlorodifluoromethyl)-4-nitro-6-                                  (trifluoromethyl)benzimidazole                                         102     ethyl 2-(chlorodifluoromethyl)-4-nitro-6-(trifluoromethyl)-1-                  benzimidazolecarboxylate                                               103     N,N-dimethyl-2-(chlorodifluoromethyl)-7-nitro-5-                               (trifluoromethyl)-thio-1-benzimidazolecarboxamide                      104     N,N-dimethyl-2-(chlorodifluoromethyl)-4-nitro-6-                               (trifluoromethyl)-thio-1-benzimidazolecarboxamide                      105     methyl 4-nitro-2-(1,1,2,2-tetrafluoroethyl)-6-(trifluoromethyl)-1-             benzimidazolecarboxylate                                               106     allyl 4-nitro-2-(1,1,2,2-tetrafluoroethyl)-6-(trifluoromethyl)-1-              benzimidazolecarboxylate                                               107     allyl 2-(chlorodifluormethyl)-4-nitro-6-(trifluoromethyl)-1-                   benzimidazolecarboxylate                                               108     1-(phenylsulfonyl)-2-(1,1,2,2-tetrafluoroethyl)-4-nitro-6-                     (trifluoromethyl)benzimidazole                                         __________________________________________________________________________

Compounds of Formula III which can be employed in the present invention include the following:

    __________________________________________________________________________     Example #                                                                              Name                                                                   __________________________________________________________________________     109     2-hydroxy-4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                              tetrafluoroethyl)benzimidazoline, sodium salt                          110     2-hydroxy-4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                              tetrafluoroethyl)benzimidazoline, tetra-n-butylammonium salt           111     2-hydroxy-4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                              tetrafluoroethyl)benzimidazoline, tetraethylammonium salt              112     2-hydroxy-4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                              tetrafluoroethyl)benzimidazoline, silver salt                          113     2-hydroxy-4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                              tetrafluoroethyl)benzimidazoline, sodium salt                          114     2-hydroxy-4-nitro-2,6-bis(trifluoromethyl)benzimidazoline,                     sodium salt                                                            115     2-hydroxy-4-nitro-2,6-bis(trifluoromethyl)benzimidazoline,                     triethylamine salt                                                     116     2-hydroxy-4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                              tetrafluoroethyl)benzimidazoline, lithium salt                         117     2-hydroxy-4-nitro-6-chloro-2-(difluoromethyl)benzimidazoline,                  hemicalcium salt                                                       118     2-hydroxy-4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-                              tetrafluoroethyl)benzimidazoline, hemicalcium salt                     __________________________________________________________________________

The polyethers are a known class of antibiotics showing common structural features. A review article is found in the Kirk-Othmer Encyclopedia of Chemical Technology--4th Ed., Volume #3, pages 306-322, and this article is incorporated herein by reference. As noted in this review article, the polyethers exhibit anticoccidial activity, and are presently the principal chemotherapeutics, worldwide, for the control of coccidiosis.

Representative polyethers which can be used in the present invention include the following; the noted reference patents are incorporated herein by reference.

    ______________________________________                                         monensin              3,501,568                                                laidlomycin                                                                    nigericin                                                                      grisorixin                                                                     dianemycin                                                                     lenoremycin                                                                    salinomycin           3,857,948                                                narasin               4,038,384                                                lonomycin                                                                      antibiotic X206                                                                allorixin                                                                      septamycin                                                                     antibiotic A204       3,705,238                                                etheromycin                                                                    lasalocid             3,719,753                                                isolasalocid                                                                   lysocellin                                                                     antibiotic A23187     4,582,822                                                portmicin (antibiotic A80190)                                                                        4,683,204                                                kijimicin                                                                      antibiotic A82810     EPO X-7412                                               maduramicin factor A (X-4868A)                                                                       4,407,946                                                maduramicin factor C (LLC-23024B)                                              semduramicin.                                                                  ______________________________________                                    

There are certain preferred embodiments of the present invention. A preferred embodiment of Formula I and II are compounds wherein the benzo ring is substituted by nitro and a single CF₃ (i.e., compounds wherein m=1 and n=0). In Formula I, the preference is for R² =trifluoroacetyl or (1,1,2,2-tetrafluoropropionyl) and R⁴ =H or the same moiety represented by R². In Formula II, the preference is for R⁵ =(1,1,2,2tetrafluoroethyl). Especially preferred compounds are:

3-nitro-5-(trifluoromethyl)-N¹ -(2,2,3,3-tetrafluoropropionyl)-o-phenylenediamine

4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-tetrafluoroethyl)benzimidazole

1-hydroxy-4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-tetrafluoroethyl)benzimidazole

Among the benzimidazolines of Formula III, preferences are the same for the benzo substitution and R⁵ ; a preferred salt is sodium (R⁶). Thus, especially preferred compounds are

2-hydroxy-4-nitro-2,6-bis(trifluoromethyl)benzimidazoline, sodium salt

2-hydroxy-4-nitro-6-(trifluoromethyl)-2-(2,2,3,3-tetrafluoroethyl)benzimidazoline, sodium salt

Among the polyethers, preferred compounds are

antibiotic A204,

portmicin,

antibiotic A82810,

maduramicin, and

semduramicin.

Combined therapy with both (1) a phenylenediamine, benzimidazole, or benzimidazoline, and (2) a polyether, is a preferred embodiment of the present invention.

The present invention can be employed for the control of coccidiosis in any fowl. Chickens and turkeys are the species most commonly treated for coccidiosis but the present invention can also be used with other poultry species, such as ducks, geese, quail, pheasants and ostriches.

The present invention can be used to prevent or treat coccidiosis attributable to any species. The species which commonly cause coccidiosis in chickens are

Eimeria acervulina

Eimeria brunetti

Eimeria maxima

Eimeria necatrix

Eimeria tenella

The species which commonly cause coccidiosis in turkeys are

Eimeria meleagrimitis

Eimeria gallopavonis

Eimeria adenoeides

Eimeria dispersa

Coccidiosis in other poultry species is attributable to yet other protozoan species known to those skilled in the art.

The present invention is useful generally for the prevention and/or treatment of coccidiosis; however, it is particularly useful regarding those coccidiosis-causing species which are insensitive to the polyethers, or which, based on laboratory trials or intensive use experience, could become insensitive. Thus, the present invention presents a technique for controlling coccidiosis while reducing the risk of developing insensitivity or resistance to the polyethers.

The present invention is practiced in the usual fashion of anticoccidials, that is, because coccidiosis is a malady of the intestinal tract, an anticoccidial must be administered in a way to reach the intestinal tract. This is typically achieved by incorporating the present agents in the feed. Anticoccidials are sometimes administered via the drinking water, and this route is possible for the compounds of Formula I, II, and III, especially in their salt forms. However, because of their low solubility, the polyethers are not readily administered by this mute. In the embodiment of the present invention which employs both a compound of Formula I, II, or III, as well as a polyether, the former can be administered by the feed and the latter via the drinking water. In the most preferred practice however, both are administered in the feed.

The present active agents are incorporated into an animal feed in the manner usual for anticoccidials. Typically, a compound of Formula I or II, or a compound of Formula I, II, and III as well as a polyether, are incorporated into a "premix." The premix contains the active agent or agents as well as physiologically acceptable carriers and feedstuffs. The premix is relatively concentrated and is adapted to be diluted with other carriers, vitamin and mineral supplements, and feedstuffs to form the final animal feed. Premixes which are intermediate in concentration of active agent between a first premix and the final animal feed are sometimes employed in the industry and can be used in implementing the present invention.

When employing a compound of Formula I or II as sole active agent, a premix desirably contains the agent at a concentration of from 0.1 to 50.0% by weight. Preferred premixes will generally contain a compound of Formula I or II at a concentration of from 0.5 to 25.0%, by weight. When employing both a compound of Formula I, II, or III, as well as a polyether, a premix desirably contains concentrations of from 0.2 to 25.0% by weight of each active agent. Combined therapy can also be obtained using one premix containing the compound of Formula I, II, or III, and a second premix containing the polyether. Both mixes are added to carriers, vitamin and mineral supplements, and feedstuffs to yield a single animal feed containing both active agents. The identity of the other components of the premix and ultimate animal feed is not critical; exemplary formulations are listed below.

Various compounds to be employed in accordance with the present invention were evaluated in a standardized chicken battery test. In this test, the respective compound was mixed well with a small portion of a basal diet, to constitute a premix, and the resulting premix was added to a large amount of the same basal diet. This resulted in the ultimate diet fed to the chickens, containing the respective compound.

The battery test was conducted with Peterson x Hubbard cockerel chicks, beginning when the chicks were approximately nine days old. There were generally four chicks per pen and three or four pens per treatment. All chicks were housed in stainless steel wire cages, 13"×21"×9". The respective diet and water were provided ad libitum beginning at approximately day nine. All birds except those of a non-infected control group were infected with two or three species of Eimeria; infection was by crop intubation of sporulated oocysts, usually two days after the trial began (in some tests, one day after the trial began). The chicks were maintained on the trial for approximately nine days at which time they were killed and the intestinal tracts evaluated for the degree of lesions attributable to coccidiosis. Other parameters evaluated during the test were mortality, weight gain, and feed/gain.

The composition of the basal feed was as follows¹ :

    ______________________________________                                         Ingredients            %                                                       ______________________________________                                         Corn, Yellow, Ground   53.42                                                   Soybean Meal (49%)     31.73                                                   Animal Fat             2.83                                                    Fish Meal-Menhaden     5.00                                                    Corn Distillers Dried Solubles                                                                        4.00                                                    Dicalcium Phosphate    1.28                                                    Ground Limestone       0.62                                                    Vitamin Premix TK-01 (1.03).sup.2                                                                     0.50                                                    Salt (NaCl)            0.30                                                    Trace Mineral Premix TK-01 (1.02).sup.3                                                               0.10                                                    Methionine Hydroxy Analog                                                                             0.17                                                    Selenium Premix.sup.3  0.05                                                    Total                  100.00                                                  ______________________________________                                          .sup.1 Final feed is in mash form.                                             .sup.2 Vitamin premix provides 3000 IU of Viatmin A, 900 ICU of Vitamin        D.sub.3, 40 mg of Vitamin E, 0.7 mg of Vitamin K, 1000 mg of choline, 70       mg of niacin, 4 mg of pantothenic acid, 4 mg of ribovlavin, 0.10 mg of         Vitamin B.sub.12, 0.10 mg of biotin and 125 mg of ethoxyquin per kg of         complete feed.                                                                 .sup.3 Trace mineral premixes provide 75 mg of Mn, 50 mg of Zn, 25 mg of       Fe, 1 mg of I, and 0.10 mg of Se per kg of complete feed.                

CALCULATED ANALYSIS

    __________________________________________________________________________     Crude Protein,                                                                         %    23.50 Vitamin K,                                                                              mg/kg 0.70                                         ME,     Kcal/kg                                                                             3100.00                                                                              Choline, mg/kg 2178.00                                      ME/CP Ratio  132.00                                                                               Niacin,  mg/kg 96.50                                        Fat,    %    5.70  Pant. Acid,                                                                             mg/kg 12.60                                        Fiber,  %    2.70  Riboflavin,                                                                             mg/kg 6.40                                         Ash,    %    6.00  Thiamine,                                                                               mg/kg 2.80                                         Calcium,                                                                               %    0.85  Folic Acid,                                                                             mg/kg 1.50                                         Total P,                                                                               %    0.77  Biotoin, mcg/kg                                                                               296.00                                       Vitamin. A,                                                                            IU/kg                                                                               4765.00                                                                              Vit. B.sub.12,                                                                          mcg/kg                                                                               107.00                                       Vitamin D.sub.3,                                                                       ICU/kg                                                                              900.00                                                                               Vitamin B.sub.6,                                                                        mg/kg 7.60                                         Vitamin E,                                                                             mg/kg                                                                               56.50                                                             Xanthophyll,                                                                           mg/kg                                                                               8.30  Linoleic Acid,                                                                          %     1.30                                         Manganese,                                                                             mg/kg                                                                               101.30                                                                               Iron,    mg/kg 119.90                                       Copper, mg/kg                                                                               17.20 Zinc,    mg/kg 85.40                                        Selenium                                                                               mcg/kg                                                                              251.00                                                                               Magnesium,                                                                              mg/kg 2003.00                                      Potassium,                                                                             mg/kg                                                                               9072.00                                                                              Sodium,  mg/kg 1670.00                                      Iodine, mg/kg                                                                               1.00  Arginine,                                                                               %     1.685                                        Lysine, %    1.41  Glycine, %     1.400                                        Methionine,                                                                            %    0.56  Cystine, %     0.356                                        TSAA,   %    0.920 Tryptophan,                                                                             %     0.333                                        __________________________________________________________________________

Results of trials in accordance with the present invention are reported in the following tables. "#" columns refer to the number of pens. Mortality is reported using both (1) due to all causes, and (2) due to coccidiosis, only. Weight gain is calculated only for surviving chicks. In most experiments, feed:gain ratio was calculated using only pens in which no mortality occurred. However, in some experiments, an adjusted feed:gain ratio was calculated by correcting for mortality. To determine what method was used to calculate feed:gain, compare the number of pens used to calculate mortality with the number of pens used to calculate feed:gain. If no mortality occurred within a particular treatment group, then all pens were used to calculate feed:gain ratio and no adjustment was necessary. If mortality occurred in a particular treatment group and there are fewer pens used for feed:gain than for mortality, then feed:gain was calculated using only pens in which mortality did not occur. However, if mortality occurred and the number of pens used to calculate mortality is equal to the number of pens used to calculate feed:gain, then an adjusted feed:gain ratio was calculated. Statistical analyses were by the Student-Newman-Keul's Multiple Range Test, using Gerbhardt's Algorithm for unequal sample size. Means within a column with no common superscript letter differ (P<.05).

    __________________________________________________________________________     EXPERIMENT NO. 1                                                               Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                         Lesion Scores                            Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                               Feed/Gain                                                                              Intestinal                                                                             Cecal                              PPM   # Total %                                                                             # % DTC                                                                               # Mean  # Mean  # Mean  # Mean                             __________________________________________________________________________     NC                                                                             0     3 0.0                                                                               b 3 0.0                                                                               a 3 272.3                                                                             a  3 1.584                                                                             b-c                                                                               3 0.00                                                                              d  3 0.00                                                                              e                             IC                                                                             0     3 8.3                                                                               b 3 8.3                                                                               a 3 221.6                                                                             a-b                                                                               2 1.737                                                                             a-c                                                                               3 6.00                                                                              a  3 3.33                                                                              a                             A82810                                                                         2     3 0.0                                                                               b 3 0.0                                                                               a 3 202.7                                                                             b  3 1.908                                                                             a  3 6.08                                                                              a  3 3.33                                                                              a                             4     3 0.0                                                                               b 3 0.0                                                                               a 3 221.4                                                                             a-b                                                                               3 1.817                                                                             a-c                                                                               3 3.83                                                                              a-c                                                                               3 3.08                                                                              a-b                           8     3 0.0                                                                               b 3 0.0                                                                               a 3 231.8                                                                             a-b                                                                               3 1.718                                                                             a-c                                                                               3 1.50                                                                              c-d                                                                               3 2.92                                                                              a-c                           Example No. 57                                                                 3     3 8.3                                                                               b 3 8.3                                                                               a 3 217.1                                                                             a-b                                                                               2 1.879                                                                             a-b                                                                               3 5.33                                                                              a-b                                                                               3 3.42                                                                              a                             6     3 8.3                                                                               b 3 8.3                                                                               a 3 221.8                                                                             a-b                                                                               2 1.715                                                                             a-c                                                                               3 2.75                                                                              b-d                                                                               3 2.92                                                                              a-c                           12    3 16.7                                                                              b 3 0.0                                                                               a 3 235.6                                                                             a-b                                                                               2 1.706                                                                             a-c                                                                               3 0.00                                                                              d  3 0.33                                                                              e                             A82810 + Example No. 57                                                        2 + 3 3 16.7                                                                              b 3 16.7                                                                              a 3 193.1                                                                             b  2 1.926                                                                             a  3 4.08                                                                              a-c                                                                               3 3.33                                                                              a                             2 + 6 3 8.3                                                                               b 3 0.0                                                                               a 3 239.8                                                                             a-b                                                                               2 1.769                                                                             a-c                                                                               3 0.58                                                                              d  3 2.56                                                                              a-d                           2 + 12                                                                               3 16.7                                                                              b 3 0.0                                                                               a 3 224.6                                                                             a-b                                                                               1 1.843                                                                             a-c                                                                               3 0.00                                                                              d  3 0.83                                                                              e                             4 + 3 3 0.0                                                                               b 3 0.0                                                                               a 3 255.4                                                                             a-b                                                                               3 1.675                                                                             a-c                                                                               3 1.00                                                                              c-d                                                                               3 2.58                                                                              a-d                           4 + 6 3 8.3                                                                               b 3 0.0                                                                               a 3 248.7                                                                             a-b                                                                               2 1.692                                                                             a-c                                                                               3 0.00                                                                              d  3 1.56                                                                              b-e                           4 + 12                                                                               3 75.0                                                                              a 3 0.0                                                                               a 3 220.9                                                                             a-b        3 1.50                                                                              c-d                                                                               3 1.17                                                                              d-e                           8 + 3 3 0.0                                                                               b 3 0.0                                                                               a 3 269.8                                                                             a  3 1.546                                                                             c  3 0.58                                                                              d  3 1.33                                                                              c-e                           8 + 6 3 8.3                                                                               b 3 0.0                                                                               a 3 257.4                                                                             a-b                                                                               2 1.710                                                                             a-c                                                                               3 0.25                                                                              d  3 0.92                                                                              e                             8 + 12                                                                               3 41.7                                                                              b 3 0.0                                                                               a 3 238.6                                                                             a-b                                                                               1 1.758                                                                             a-c                                                                               3 0.00                                                                              d  3 0.33                                                                              e                             __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 2                                                               Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. maxima and E. tenella                                                                                             Lesion Scores                            Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                               Feed/Gain                                                                              Intestinal                                                                             Cecal                              PPM   # Total %                                                                             # % DTC                                                                               # Mean  # Mean  # Mean  # Mean                             __________________________________________________________________________     NC                                                                             0     3 8.3                                                                               a 3 0.0                                                                               a 3 276.8                                                                             a  2 1.537                                                                             b  3 0.00                                                                              d  3 0.00                                                                              c                             IC                                                                             0     3 25.0                                                                              a 3 16.7                                                                              a 3 174.1                                                                             d-e        3 7.50                                                                              a-b                                                                               3 3.44                                                                              a                             A82810                                                                         2     3 8.3                                                                               a 3 8.3                                                                               a 3 154.6                                                                             e  2 2.332                                                                             a  3 8.75                                                                              a  3 3.42                                                                              a                             4     3 0.0                                                                               a 3 0.0                                                                               a 3 172.2                                                                             d-e                                                                               3 2.053                                                                             a-b                                                                               3 7.83                                                                              a-b                                                                               3 3.08                                                                              a                             8     3 0.0                                                                               a 3 0.0                                                                               a 3 230.0                                                                             a-d                                                                               3 1.667                                                                             b  3 8.00                                                                              a-b                                                                               3 3.08                                                                              a                             Example No. 57                                                                 3     3 0.0                                                                               a 3 0.0                                                                               a 3 180.0                                                                             d-e                                                                               3 2.065                                                                             a-b                                                                               3 8.75                                                                              a  3 3.50                                                                              a                             6     3 8.3                                                                               a 3 8.3                                                                               a 3 184.6                                                                             c-e                                                                               2 2.079                                                                             a-b                                                                               3 8.42                                                                              a  3 3.58                                                                              a                             12    3 41.7                                                                              a 3 0.0                                                                               a 3 235.8                                                                             a-d                                                                               1 1.725                                                                             a-b                                                                               3 3.00                                                                              c-d                                                                               3 1.25                                                                              b-c                           A82810 + Example No. 57                                                        2 + 3 3 0.0                                                                               a 3 0.0                                                                               a 3 201.2                                                                             b-e                                                                               3 1.870                                                                             a-b                                                                               3 7.00                                                                              a-b                                                                               3 3.33                                                                              a                             2 + 6 3 8.3                                                                               a 3 0.0                                                                               a 3 249.8                                                                             a-c                                                                               2 1.626                                                                             b  3 1.00                                                                              d  3 1.03                                                                              b-c                           2 + 12                                                                               3 16.7                                                                              a 3 0.0                                                                               a 3 215.7                                                                             a-e                                                                               1 1.881                                                                             a-b                                                                               3 0.00                                                                              d  3 0.33                                                                              c                             4 + 3 3 25.0                                                                              a 3 0.0                                                                               a 3 229.0                                                                             a-d                                                                               1 1.698                                                                             a-b                                                                               3 7.78                                                                              a-b                                                                               3 3.06                                                                              a                             4 + 6 3 0.0                                                                               a 3 0.0                                                                               a 3 245.8                                                                             a-c                                                                               3 1.693                                                                             b  3 1.58                                                                              d  3 2.08                                                                              a-b                           4 + 12                                                                               3 41.7                                                                              a 3 0.0                                                                               a 2 211.3                                                                             a-e                                                                               1 1.808                                                                             a-b                                                                               2 0.00                                                                              d  2 0.00                                                                              c                             8 + 3 3 8.3                                                                               a 3 0.0                                                                               a 3 258.3                                                                             a-b                                                                               2 1.608                                                                             b  3 4.83                                                                              b-c                                                                               3 2.06                                                                              a-b                           8 + 6 3 8.3                                                                               a 3 0.0                                                                               a 3 255.5                                                                             a-b                                                                               2 1.513                                                                             b  3 1.00                                                                              d  3 0.50                                                                              c                             8 + 12                                                                               3 25.0                                                                              a 3 0.0                                                                               a 3 215.2                                                                             a-e                                                                               1 1.813                                                                             a-b                                                                               3 0.00                                                                              d  3 0.00                                                                              c                             __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 3                                                               Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. acervulina                                                                                         Lesion Scores                            Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                               Feed/Gain                                                                              Intestinal                                                                             Cecal                              PPM   # Total %                                                                             # % DTC                                                                               # Mean  # Mean  # Mean  # Mean                             __________________________________________________________________________     NC                                                                             0     3 0.0                                                                               b 3 0.0                                                                               b 3 274.8                                                                             a  3 1.549                                                                             b  3 0.00                                                                              d  3 0.00                                                                              d                             IC                                                                             0     3 16.7                                                                              b 3 16.7                                                                              a 3 195.2                                                                             b  1 2.305                                                                             a-b                                                                               3 5.25                                                                              a  3 3.67                                                                              a                             A82810                                                                         2     3 0.0                                                                               b 3 0.0                                                                               b 3 228.6                                                                             a-b                                                                               3 1.886                                                                             a-b                                                                               3 2.00                                                                              b  3 2.67                                                                              b                             4     3 0.0                                                                               b 3 0.0                                                                               b 3 255.2                                                                             a  3 1.762                                                                             b  3 1.25                                                                              c  3 3.42                                                                              a-b                           8     3 0.0                                                                               b 3 0.0                                                                               b 3 244.2                                                                             a  3 1.772                                                                             b  3 1.17                                                                              c  3 3.33                                                                              a-b                           Example No. 113                                                                6     3 0.0                                                                               b 3 0.0                                                                               b 3 244.7                                                                             a  3 1.747                                                                             b  3 0.58                                                                              d  3 1.50                                                                              c                             12    3 0.0                                                                               b 3 0.0                                                                               b 3 182.1                                                                             b  3 2.105                                                                             a-b                                                                               3 0.00                                                                              d  3 0.17                                                                              d                             A82810 + Example No. 113                                                       2 + 6 3 0.0                                                                               b 3 0.0                                                                               b 3 245.5                                                                             a  3 1.772                                                                             b  3 0.00                                                                              d  3 0.58                                                                              d                             2 + 12                                                                               3 8.3                                                                               b 3 0.0                                                                               b 3 192.3                                                                             b  2 2.125                                                                             a-b                                                                               3 0.00                                                                              d  3 0.00                                                                              d                             4 + 6 3 0.0                                                                               b 3 0.0                                                                               b 3 251.8                                                                             a  3 1.731                                                                             b  3 0.00                                                                              d  3 0.75                                                                              d                             4 + 12                                                                               3 16.7                                                                              b 3 0.0                                                                               b 3 193.9                                                                             b  1 2.006                                                                             a-b                                                                               3 0.00                                                                              d  3 0.19                                                                              d                             8 + 6 3 8.3                                                                               b 3 0.0                                                                               b 3 254.0                                                                             a  2 1.839                                                                             a-b                                                                               3 0.00                                                                              d  3 0.39                                                                              d                             8 + 12                                                                               3 0.0                                                                               b 3 0.0                                                                               b 3 185.7                                                                             b  3 2.323                                                                             a  3 0.00                                                                              d  3 0.00                                                                              d                             8 + 24                                                                               1 75.0                                                                              a 1 0.0                                                                               b 1 67.0                                                                              c          1 0.00                                                                              d  1 0.00                                                                              d                             __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 4                                                               Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. maxima                                                                                             Lesion Scores                            Treatment                                                                            Mortality Mean Wt. Gain                                                                               Feed/Gain                                                                              Intestinal                                                                             Cecal                             PPM   # Total %                                                                              # % DTC                                                                               # Mean  # Mean  # Mean  # Mean                            __________________________________________________________________________     NC                                                                             0     3 0.0                                                                               c  3 0.0                                                                               b 3 295.8                                                                             a  3 1.578                                                                             d  3 0.00                                                                              c  3 0.00                                                                              c                            IC                                                                             0     3 33.3                                                                              b-c                                                                               3 33.3                                                                              a 3 170.3                                                                             b-d        3 5.33                                                                              b  3 3.75                                                                              a                            A82810                                                                         2     3 41.7                                                                              b  3 41.7                                                                              a 3 138.4                                                                             d          3 6.42                                                                              b  3 3.75                                                                              a                            4     3 25.0                                                                              b-c                                                                               3 16.7                                                                              b 3 160.0                                                                             c-d                                                                               1 2.368                                                                             a  3 7.17                                                                              a-b                                                                               3 3.56                                                                              a                            8     3 0.0                                                                               c  3 0.0                                                                               b 3 208.3                                                                             b-d                                                                               3 1.978                                                                             a-c                                                                               3 8.67                                                                              a  3 3.58                                                                              a                            Example No. 113                                                                6     3 0.0                                                                               c  3 0.0                                                                               b 3 242.4                                                                             a-c                                                                               3 1.681                                                                             c-d                                                                               3 2.42                                                                              c  3 1.08                                                                              b                            12    3 16.7                                                                              b-c                                                                               3 0.0                                                                               b 3 180.4                                                                             b-d                                                                               2 2.130                                                                             a-b                                                                               3 0.00                                                                              c  3 0.00                                                                              c                            A82810 + Example No. 113                                                       2 + 6 3 0.0                                                                               c  3 0.0                                                                               b 3 251.0                                                                             a-b                                                                               3 1.771                                                                             b-d                                                                               3 0.17                                                                              c  3 0.83                                                                              b-c                          2 + 12                                                                               3 0.0                                                                               c  3 0.0                                                                               b 3 198.3                                                                             b-d                                                                               3 2.011                                                                             a-c                                                                               3 0.00                                                                              c  3 0.00                                                                              c                            4 + 6 3 0.0                                                                               c  3 0.0                                                                               b 3 241.7                                                                             a-c                                                                               3 1.783                                                                             b-d                                                                               3 0.00                                                                              c  3 0.25                                                                              c                            4 + 12                                                                               3 0.0                                                                               c  3 0.0                                                                               b 3 190.3                                                                             b-d                                                                               3 2.149                                                                             a-b                                                                               3 0.00                                                                              c  3 0.00                                                                              c                            4 + 24                                                                               2 75.0                                                                              a  2 0.0                                                                               b 2 72.8                                                                              e          2 0.00                                                                              c  2 0.00                                                                              c                            8 + 6 3 0.0                                                                               c  3 0.0                                                                               b 3 242.3                                                                             a-c                                                                               3 1.782                                                                             b-d                                                                               3 0.08                                                                              c  3 0.25                                                                              c                            8 + 12                                                                               3 8.3                                                                               c  3 0.0                                                                               b 3 163.0                                                                             c-d                                                                               2 2.235                                                                             a  3 0.00                                                                              c  3 0.00                                                                              c                            __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 5                                                               Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                     Lesion Scores                                Treatment                                                                              Mortality Mean                                                                             Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                             Cecal                                PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean  # Mean                               __________________________________________________________________________     NC                                                                             0     3 0.0                                                                               a 3 0.0                                                                               a 3 252.6                                                                             a 3 1.677                                                                             a 3 0.00                                                                              c  3 0.00                                                                              e                               IC                                                                             0     3 0.0                                                                               a 3 0.0                                                                               a 3 205.6                                                                             a 3 2.059                                                                             a 3 5.67                                                                              a  3 2.92                                                                              a-b                             A82810                                                                         2     3 0.0                                                                               a 3 0.0                                                                               a 3 226.1                                                                             a 3 1.894                                                                             a 3 4.83                                                                              a  3 2.92                                                                              a-b                             4     3 8.3                                                                               a 3 0.0                                                                               a 3 254.1                                                                             a 2 1.612                                                                             a 3 1.42                                                                              b-c                                                                               3 3.11                                                                              a-b                             8     3 0.0                                                                               a 3 0.0                                                                               a 3 252.5                                                                             a 3 1.802                                                                             a 3 0.92                                                                              b-c                                                                               3 1.83                                                                              a-d                             Example No. 57                                                                 2     3 16.7                                                                              a 3 0.0                                                                               a 3 212.4                                                                             a 1 1.878                                                                             a 3 5.00                                                                              a  3 3.44                                                                              a                               4     3 16.7                                                                              a 3 0.0                                                                               a 3 208.2                                                                             a 1 2.025                                                                             a 3 4.06                                                                              a  3 3.06                                                                              a-b                             8     3 16.7                                                                              a 3 8.3                                                                               a 3 233.7                                                                             a 1 1.829                                                                             a 3 1.28                                                                              b-c                                                                               3 3.39                                                                              a-b                             A82810 + Example No. 57                                                        2 + 2 3 8.3                                                                               a 3 8.3                                                                               a 3 225.5                                                                             a 2 1.862                                                                             a 3 3.17                                                                              a-b                                                                               3 2.58                                                                              a-c                             2 + 4 3 8.3                                                                               a 3 0.0                                                                               a 3 236.0                                                                             a 2 1.735                                                                             a 3 1.14                                                                              b-c                                                                               3 2.25                                                                              a-d                             2 + 8 3 16.7                                                                              a 3 0.0                                                                               a 3 214.6                                                                             a 1 1.915                                                                             a 3 0.08                                                                              c  3 0.86                                                                              c-e                             4 + 2 3 0.0                                                                               a 3 0.0                                                                               a 3 232.2                                                                             a 3 1.723                                                                             a 3 1.92                                                                              b-c                                                                               3 2.00                                                                              a-d                             4 + 4 3 0.0                                                                               a 3 0.0                                                                               a 3 221.8                                                                             a 3 1.903                                                                             a 3 0.42                                                                              b-c                                                                               3 1.42                                                                              b-e                             4 + 8 3 8.3                                                                               a 3 0.0                                                                               a 3 236.4                                                                             a 2 1.715                                                                             a 3 0.00                                                                              c  3 0.58                                                                              d-e                             8 + 2 3 0.0                                                                               a 3 0.0                                                                               a 3 245.3                                                                             a 3 1.714                                                                             a 3 0.67                                                                              b-c                                                                               3 1.50                                                                              a-e                             8 + 4 3 0.0                                                                               a 3 0.0                                                                               a 3 259.0                                                                             a 3 1.624                                                                             a 3 0.33                                                                              b-c                                                                               3 1.58                                                                              a-e                             8 + 8 3 0.0                                                                               a 3 0.0                                                                               a 3 248.5                                                                             a 3 1.660                                                                             a 3 0.00                                                                              c  3 0.00                                                                              e                               __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 6                                                               Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. maxima and E. tenella                                                                                           Lesion Scores                              Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                               Feed/Gain                                                                              Intestinal                                                                             Cecal                              PPM   # Total %                                                                             # % DTC                                                                               # Mean  # Mean  # Mean  # Mean                             __________________________________________________________________________     NC                                                                             0     3 8.3                                                                               b 3 0.0                                                                               b 3 254.8                                                                             a  2 1.806                                                                             a  3 0.00                                                                              c  3 0.22                                                                              c                             IC                                                                             0     3 0.0                                                                               b 3 0.0                                                                               b 3 165.6                                                                             b-c                                                                               3 2.182                                                                             a  3 8.92                                                                              a  3 3.00                                                                              a                             A82810                                                                         2     3 8.3                                                                               b 3 8.3                                                                               b 3 195.1                                                                             a-c                                                                               2 1.957                                                                             a  3 8.25                                                                              a  3 3.25                                                                              a                             4     3 8.3                                                                               b 3 0.0                                                                               b 3 189.8                                                                             a-c                                                                               2 2.083                                                                             a  3 7.39                                                                              a  3 3.19                                                                              a                             8     3 0.0                                                                               b 3 0.0                                                                               b 3 217.9                                                                             a-b                                                                               3 1.863                                                                             a  3 8.83                                                                              a  3 2.67                                                                              a                             Example No. 57                                                                 2     3 41.7                                                                              a 3 33.3                                                                              a 3 126.4                                                                             c          3 8.33                                                                              a  3 3.50                                                                              a                             4     3 8.3                                                                               b 3 8.3                                                                               b 3 177.8                                                                             a-c                                                                               2 2.048                                                                             a  3 8.25                                                                              a  3 3.08                                                                              a                             8     3 0.0                                                                               b 3 0.0                                                                               b 3 217.2                                                                             a-b                                                                               3 1.860                                                                             a  3 6.50                                                                              a-b                                                                               3 2.50                                                                              a-b                           A82810 + Example No. 57                                                        2 + 2 3 8.3                                                                               b 3 0.0                                                                               b 3 178.3                                                                             a-c                                                                               2 2.170                                                                             a  3 8.50                                                                              a  3 3.17                                                                              a                             2 + 4 3 0.0                                                                               b 3 0.0                                                                               b 3 221.8                                                                             a-b                                                                               3 1.840                                                                             a  3 5.67                                                                              a-b                                                                               3 3.00                                                                              a                             2 + 8 3 8.3                                                                               b 3 0.0                                                                               b 3 226.6                                                                             a-b                                                                               2 1.798                                                                             a  3 0.89                                                                              c  3 1.08                                                                              c                             4 + 2 3 8.3                                                                               b 3 0.0                                                                               b 3 226.5                                                                             a-b                                                                               2 1.728                                                                             a  3 7.50                                                                              a  3 3.06                                                                              a                             4 + 4 3 0.0                                                                               b 3 0.0                                                                               b 3 242.6                                                                             a-b                                                                               3 1.713                                                                             a  3 6.17                                                                              a-b                                                                               3 2.25                                                                              a-b                           4 + 8 3 8.3                                                                               b 3 0.0                                                                               b 3 248.1                                                                             a-b                                                                               2 1.721                                                                             a  3 0.00                                                                              c  3 0.25                                                                              c                             8 + 2 3 0.0                                                                               b 3 0.0                                                                               b 3 226.8                                                                             a-b                                                                               3 1.750                                                                             a  3 4.33                                                                              a-b                                                                               3 0.83                                                                              c                             8 + 4 3 0.0                                                                               b 3 0.0                                                                               b 3 231.5                                                                             a-b                                                                               3 1.756                                                                             a  3 2.58                                                                              b-c                                                                               3 1.42                                                                              b-c                           8 + 8 3 16.7                                                                              b 3 0.0                                                                               b 3 238.6                                                                             a-b                                                                               1 1.730                                                                             a  3 0.00                                                                              c  3 0.33                                                                              c                             __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 7                                                               Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. acervulina                                                                                       Lesion Scores                              Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                               Feed/Gain                                                                              Intestinal                                                                             Cecal                              PPM   # Total %                                                                             # % DTC                                                                               # Mean  # Mean  # Mean  # Mean                             __________________________________________________________________________     NC                                                                             0     3 0.0                                                                               a 3 0.0                                                                               a 3 299.0                                                                             a  3 1.549                                                                             e  3 0.00                                                                              e  3 0.08                                                                              f                             IC                                                                             0     3 8.3                                                                               a 3 8.3                                                                               a 3 221.4                                                                             c-e                                                                               2 1.922                                                                             a-b                                                                               3 5.58                                                                              a  3 3.42                                                                              a                             A82810                                                                         2     3 0.0                                                                               a 3 0.0                                                                               a 3 234.4                                                                             b-e                                                                               3 1.814                                                                             a-d                                                                               3 2.83                                                                              c-d                                                                               3 2.92                                                                              a-b                           4     3 0.0                                                                               a 3 0.0                                                                               a 3 264.3                                                                             a-c                                                                               3 1.667                                                                             b-e                                                                               3 4.33                                                                              b  3 3.00                                                                              a-b                           8     3 0.0                                                                               a 3 0.0                                                                               a 3 270.5                                                                             a-c                                                                               3 1.645                                                                             c-e                                                                               3 1.67                                                                              d-e                                                                               3 3.00                                                                              a-b                           Example No. 113                                                                2     3 0.0                                                                               a 3 0.0                                                                               a 3 211.5                                                                             d-e                                                                               3 1.868                                                                             a-c                                                                               3 3.50                                                                              b-c                                                                               3 3.08                                                                              a-b                           4     3 0.0                                                                               a 3 0.0                                                                               a 3 251.8                                                                             a-e                                                                               3 1.685                                                                             b-e                                                                               3 0.42                                                                              e  3 2.17                                                                              b-c                           8     3 0.0                                                                               a 3 0.0                                                                               a 3 231.3                                                                             b-e                                                                               3 1.813                                                                             a-d                                                                               3 0.00                                                                              e  3 0.75                                                                              d-f                           A82810 + Example No. 113                                                       2 + 2 3 16.7                                                                              a 3 0.0                                                                               a 3 270.2                                                                             a-c                                                                               1 1.780                                                                             a-e                                                                               3 1.42                                                                              d-e                                                                               3 3.06                                                                              a-b                           2 + 4 3 0.0                                                                               a 3 0.0                                                                               a 3 257.1                                                                             a-d                                                                               3 1.712                                                                             b-e                                                                               3 0.42                                                                              e  3 1.67                                                                              c-d                           2 + 8 3 0.0                                                                               a 3 0.0                                                                               a 3 231.2                                                                             b-e                                                                               3 1.758                                                                             b-e                                                                               3 0.00                                                                              e  3 0.00                                                                              f                             4 + 2 3 8.3                                                                               a 3 0.0                                                                               a 3 267.2                                                                             a-c                                                                               2 1.590                                                                             d-e                                                                               3 0.83                                                                              e  3 2.19                                                                              b-c                           4 + 4 3 8.3                                                                               a 3 0.0                                                                               a 3 277.9                                                                             a-b                                                                               2 1.566                                                                             d-e                                                                               3 0.11                                                                              e  3 0.50                                                                              e-f                           4 + 8 3 0.0                                                                               a 3 0.0                                                                               a 3 229.5                                                                             b-e                                                                               3 1.799                                                                             a-d                                                                               3 0.00                                                                              e  3 0.42                                                                              e-f                           8 + 2 3 0.0                                                                               a 3 0.0                                                                               a 3 284.8                                                                             a  3 1.530                                                                             e  3 0.08                                                                              e  3 1.17                                                                              d-e                           8 + 4 3 0.0                                                                               a 3 0.0                                                                               a 3 267.0                                                                             a-c                                                                               3 1.629                                                                             d-e                                                                               3 0.00                                                                              e  3 0.75                                                                              d-f                           8 + 8 3 16.7                                                                              a 3 0.0                                                                               a 3 205.6                                                                             e  2 2.014                                                                             a  3 0.00                                                                              e  3 0.00                                                                              f                             __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 8                                                               Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. maxima and E. tenella                                                                                           Lesion Scores                              Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                               Feed/Gain                                                                              Intestinal                                                                             Cecal                              PPM   # Total %                                                                             # % DTC                                                                               # Mean  # Mean  # Mean  # Mean                             __________________________________________________________________________     NC                                                                             0     3 0.0                                                                               a 3 0.0                                                                               b 3 258.2                                                                             a-b                                                                               3 1.727                                                                             b  3 0.33                                                                              d  3 0.00                                                                              d                             IC                                                                             0     3 25.0                                                                              a 3 25.0                                                                              a 3 162.7                                                                             d  1 2.379                                                                             a  3 8.58                                                                              a  3 3.08                                                                              a-b                           A82810                                                                         2     3 0.0                                                                               a 3 0.0                                                                               b 3 174.8                                                                             c-d                                                                               3 2.205                                                                             a-b                                                                               3 8.83                                                                              a  3 2.92                                                                              a-b                           4     3 0.0                                                                               a 3 0.0                                                                               b 3 202.3                                                                             a-d                                                                               3 2.001                                                                             a-b                                                                               3 8.92                                                                              a  3 3.25                                                                              a                             8     3 0.0                                                                               a 3 0.0                                                                               b 3 216.0                                                                             a-d                                                                               3 1.976                                                                             a-b                                                                               3 8.42                                                                              a  3 3.33                                                                              a                             Example No. 113                                                                2     3 16.7                                                                              a 3 8.3                                                                               b 3 176.7                                                                             c-d                                                                               1 2.207                                                                             a-b                                                                               3 8.44                                                                              a  3 2.86                                                                              a-b                           4     3 8.3                                                                               a 3 0.0                                                                               b 3 231.1                                                                             a-d                                                                               2 1.789                                                                             a-b                                                                               3 7.67                                                                              a  3 2.75                                                                              a-b                           8     3 0.0                                                                               a 3 0.0                                                                               b 3 230.3                                                                             a-d                                                                               3 1.834                                                                             a-b                                                                               3 1.42                                                                              c-d                                                                               3 0.42                                                                              c-d                           A82810 + Example No. 113                                                       2 + 2 3 0.0                                                                               a 3 0.0                                                                               b 3 246.1                                                                             a-c                                                                               3 1.711                                                                             b  3 8.17                                                                              a  3 3.08                                                                              a-b                           2 + 4 3 8.3                                                                               a 3 0.0                                                                               b 3 243.0                                                                             a-c                                                                               2 1.743                                                                             a-b                                                                               3 1.42                                                                              c-d                                                                               3 1.31                                                                              c                             2 + 8 3 8.3                                                                               a 3 0.0                                                                               b 3 220.9                                                                             a-d                                                                               2 1.791                                                                             a-b                                                                               3 0.00                                                                              d  3 0.17                                                                              d                             4 + 2 3 0.0                                                                               a 3 0.0                                                                               b 3 276.3                                                                             a  3 1.636                                                                             b  3 5.25                                                                              b  3 2.08                                                                              b                             4 + 4 3 0.0                                                                               a 3 0.0                                                                               b 3 258.8                                                                             a-b                                                                               3 1.668                                                                             b  3 0.58                                                                              d  3 0.92                                                                              c-d                           4 + 8 3 0.0                                                                               a 3 0.0                                                                               b 3 232.0                                                                             a-d                                                                               3 1.776                                                                             a-b                                                                               3 0.33                                                                              d  3 0.17                                                                              d                             8 + 2 3 0.0                                                                               a 3 0.0                                                                               b 3 258.9                                                                             a-b                                                                               3 1.707                                                                             b  3 3.17                                                                              c  3 1.08                                                                              c-d                           8 + 4 3 0.0                                                                               a 3 0.0                                                                               b 3 259.3                                                                             a-b                                                                               3 1.634                                                                             b  3 0.00                                                                              d  3 0.00                                                                              d                             8 + 8 3 0.0                                                                               a 3 0.0                                                                               b 3 192.9                                                                             b-d                                                                               3 2.100                                                                             a-b                                                                               3 0.42                                                                              d  3 0.00                                                                              d                             __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 9                                                               Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. acervulina                                                                                       Lesion Scores                              Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                               Feed/Gain                                                                              Intestinal                                                                             Cecal                              PPM   # Total %                                                                             # % DTC                                                                               # Mean  # Mean  # Mean  # Mean                             __________________________________________________________________________     NC                                                                             0     3 8.3                                                                               b 3 0.0                                                                               b 3 323.5                                                                             a  2 1.410                                                                             c  3 0.00                                                                              b  3 0.00                                                                              f                             IC                                                                             0     3 16.7                                                                              b 3 16.7                                                                              a 3 248.1                                                                             b-d                                                                               1 1.917                                                                             a-b                                                                               3 7.25                                                                              a  3 3.75                                                                              a                             A82810 + Example No. 23                                                        2 + 2 3 0.0                                                                               b 3 0.0                                                                               b 3 265.0                                                                             a-d                                                                               3 1.714                                                                             a-c                                                                               3 0.75                                                                              b  3 3.42                                                                              a                             2 + 4 3 0.0                                                                               b 3 0.0                                                                               b 3 257.9                                                                             b-d                                                                               3 1.622                                                                             b-c                                                                               3 0.17                                                                              b  3 2.00                                                                              b-c                           2 + 8 3 0.0                                                                               b 3 0.0                                                                               b 3 252.2                                                                             b-d                                                                               3 1.691                                                                             a-c                                                                               3 0.00                                                                              b  3 0.58                                                                              e-f                           4 + 2 3 8.3                                                                               b 3 8.3                                                                               b 3 292.5                                                                             a-c                                                                               2 1.482                                                                             b-c                                                                               3 0.00                                                                              b  3 1.83                                                                              b-d                           4 + 4 3 0.0                                                                               b 3 0.0                                                                               b 3 290.2                                                                             a-c                                                                               3 1.566                                                                             b-c                                                                               3 0.00                                                                              b  3 1.42                                                                              c-f                           4 + 8 3 0.0                                                                               b 3 0.0                                                                               b 3 265.3                                                                             a-d                                                                               3 1.623                                                                             b-c                                                                               3 0.00                                                                              b  3 0.42                                                                              f                             8 + 2 3 0.0                                                                               b 3 0.0                                                                               b 3 300.8                                                                             a-b                                                                               3 1.555                                                                             b-c                                                                               3 0.00                                                                              b  3 0.00                                                                              f                             8 + 4 3 0.0                                                                               b 3 0.0                                                                               b 3 292.3                                                                             a-c                                                                               3 1.565                                                                             b-c                                                                               3 0.00                                                                              b  3 0.25                                                                              f                             8 + 8 3 0.0                                                                               b 3 0.0                                                                               b 3 244.3                                                                             b-d                                                                               3 1.772                                                                             a-c                                                                               3 0.00                                                                              b  3 0.00                                                                              f                             A82810 + Example No. 39                                                        2 + 2 3 8.3                                                                               b 3 0.0                                                                               b 3 303.9                                                                             a-b                                                                               2 1.578                                                                             b-c                                                                               3 0.28                                                                              b  3 2.83                                                                              a-b                           2 + 4 3 16.7                                                                              b 3 0.0                                                                               b 3 263.3                                                                             a-d                                                                               1 1.658                                                                             a-c                                                                               3 0.00                                                                              b  3 1.75                                                                              b-e                           2 + 8 3 50.0                                                                              a 3 0.0                                                                               b 3 230.9                                                                             c-d        3 0.00                                                                              b  3 0.22                                                                              f                             4 + 2 3 0.0                                                                               b 3 0.0                                                                               b 3 280.3                                                                             a-c                                                                               3 1.554                                                                             b-c                                                                               3 0.00                                                                              b  3 1.08                                                                              c-f                           4 + 4 3 8.3                                                                               b 3 0.0                                                                               b 3 275.5                                                                             a-c                                                                               2 1.644                                                                             b-c                                                                               3 0.00                                                                              b  3 0.72                                                                              d-f                           4 + 8 3 16.7                                                                              b 3 0.0                                                                               b 3 212.2                                                                             d  2 2.025                                                                             a  3 0.00                                                                              b  3 0.00                                                                              f                             8 + 2 3 8.3                                                                               b 3 0.0                                                                               b 3 283.0                                                                             a-c                                                                               2 1.572                                                                             b-c                                                                               3 0.00                                                                              b  3 0.00                                                                              f                             8 + 4 3 16.7                                                                              b 3 0.0                                                                               b 3 273.8                                                                             a-c                                                                               1 1.804                                                                             a-c                                                                               3 0.00                                                                              b  3 0.19                                                                              f                             8 + 8 3 0.0                                                                               b 3 0.0                                                                               b 3 233.3                                                                             c-d                                                                               3 1.851                                                                             a-b                                                                               3 0.00                                                                              b  3 0.00                                                                              f                             __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 10                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. maxima                                                                                           Lesion Scores                              Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                               Feed/Gain                                                                              Intestinal                                                                             Cecal                              PPM   # Total %                                                                             # % DTC                                                                               # Mean  # Mean  # Mean  # Mean                             __________________________________________________________________________     NC                                                                             0     3 0. 0                                                                              a 3 0.0                                                                               b 3 317.3                                                                             a  3 1.487                                                                             c-d                                                                               3 0.42                                                                              b  3 0.00                                                                              e                             IC                                                                             0     3 16.7                                                                              a 3 16.7                                                                              a 3 246.0                                                                             c-e                                                                               1 1.955                                                                             a  3 5.50                                                                              a  3 3.83                                                                              a                             A82810 + Example No. 23                                                        2 + 2 3 0.0                                                                               a 3 0.0                                                                               b 3 302.6                                                                             a-c                                                                               3 1.547                                                                             c-d                                                                               3 1.33                                                                              b  3 2.58                                                                              b                             2 + 4 3 0.0                                                                               a 3 0.0                                                                               b 3 302.8                                                                             a-c                                                                               3 1.485                                                                             c-d                                                                               3 0.83                                                                              b  3 2.00                                                                              b-c                           2 + 8 3 0.0                                                                               a 3 0.0                                                                               b 3 262.5                                                                             a-d                                                                               3 1.641                                                                             a-d                                                                               3 0.42                                                                              b  3 0.83                                                                              c-e                           4 + 2 3 0.0                                                                               a 3 0.0                                                                               b 3 307.1                                                                             a-c                                                                               3 1.456                                                                             d  3 0.83                                                                              b  3 1.58                                                                              c-d                           4 + 4 3 0.0                                                                               a 3 0.0                                                                               b 3 304.1                                                                             a-c                                                                               3 1.560                                                                             c-d                                                                               3 0.83                                                                              b  3 0.42                                                                              d-e                           4 + 8 3 0.0                                                                               a 3 0.0                                                                               b 3 263.2                                                                             a-d                                                                               3 1.640                                                                             a-d                                                                               3 0.08                                                                              b  3 0.25                                                                              e                             8 + 2 3 8.3                                                                               a 3 0.0                                                                               b 3 301.1                                                                             a-c                                                                               2 1.480                                                                             c-d                                                                               3 0.00                                                                              b  3 0.00                                                                              e                             8 + 4 3 0.0                                                                               a 3 0.0                                                                               b 3 286.3                                                                             a-c                                                                               3 1.606                                                                             b-d                                                                               3 0.33                                                                              b  3 0.00                                                                              e                             8 + 8 3 8.3                                                                               a 3 0.0                                                                               b 3 252.4                                                                             b-e                                                                               2 1.766                                                                             a-c                                                                               3 0.00                                                                              b  3 0.00                                                                              e                             A82810 + Example No. 39                                                        2 + 2 3 8.3                                                                               a 3 0.0                                                                               b 3 292.1                                                                             a-c                                                                               2 1.512                                                                             c-d                                                                               3 4.19                                                                              a  3 3.42                                                                              a                             2 + 4 3 8.3                                                                               a 3 0.0                                                                               b 3 267.8                                                                             a-d                                                                               2 1.657                                                                             a-d                                                                               3 1.61                                                                              b  3 1.19                                                                              c-e                           2 + 8 3 25.0                                                                              a 3 0.0                                                                               b 3 221.5                                                                             d-f        3 1.67                                                                              b  3 1.00                                                                              c-e                           4 + 2 3 0.0                                                                               a 3 0.0                                                                               b 3 271.3                                                                             a-d                                                                               3 1.651                                                                             a-d                                                                               3 0.42                                                                              b  3 1.00                                                                              c-e                           4 + 4 3 25.0                                                                              a 3 0.0                                                                               b 3 257.4                                                                             a-e                                                                               2 1.624                                                                             a-d                                                                               3 0.25                                                                              b  3 1.00                                                                              c-e                           4 + 8 3 41.7                                                                              a 3 0.0                                                                               b 3 186.9                                                                             f  1 1.888                                                                             a-b                                                                               3 0.33                                                                              b  3 0.33                                                                              e                             8 + 2 3 0.0                                                                               a 3 0.0                                                                               b 3 312.1                                                                             a-b                                                                               3 1.532                                                                             c-d                                                                               3 0.17                                                                              b  3 0.00                                                                              e                             8 + 4 3 25.0                                                                              a 3 0.0                                                                               b 3 275.1                                                                             a-d                                                                               1 1.616                                                                             a-d                                                                               3 0.33                                                                              b  3 0.44                                                                              d-3                           8 + 8 3 25.0                                                                              a 3 0.0                                                                               b 3 207.1                                                                             e-f                                                                               1 1.952                                                                             a  3 0.17                                                                              b  3 0.08                                                                              e                             __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 11                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. acervulina                                                                                       Lesion Scores                              Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                               Feed/Gain                                                                              Intestinal                                                                             Cecal                              PPM   # Total %                                                                             # % DTC                                                                               # Mean  # Mean  # Mean  # Mean                             __________________________________________________________________________     NC                                                                             0     3 8.3                                                                               a 3 0.0                                                                               a 3 298.0                                                                             a-b                                                                               2 1.427                                                                             d  3 0.00                                                                              b  3 0.00                                                                              b                             IC                                                                             0     3 0.0                                                                               a 3 0.0                                                                               a 3 249.6                                                                             b-e                                                                               3 1.706                                                                             a-d                                                                               3 5.25                                                                              a  3 3.33                                                                              a                             A82810 + Example No. 113                                                       2 + 2 3 8.3                                                                               a 3 0.0                                                                               a 3 309.8                                                                             a  2 1.456                                                                             c-d                                                                               3 0.00                                                                              b  3 0.58                                                                              b                             2 + 4 3 0.0                                                                               a 3 0.0                                                                               a 3 283.8                                                                             a-c                                                                               3 1.585                                                                             b-d                                                                               3 0.00                                                                              b  3 0.00                                                                              b                             2 + 8 3 0.0                                                                               a 3 0.0                                                                               a 3 235.2                                                                             c-e                                                                               3 1.787                                                                             a-b                                                                               3 0.00                                                                              b  3 0.00                                                                              b                             4 + 2 3 0.0                                                                               a 3 0.0                                                                               a 3 287.3                                                                             a-b                                                                               3 1.496                                                                             b-d                                                                               3 0.00                                                                              b  3 0.00                                                                              b                             4 + 4 3 8.3                                                                               a 3 0.0                                                                               a 3 286.4                                                                             a-c                                                                               2 1.557                                                                             b-d                                                                               3 0.00                                                                              b  3 0.00                                                                              b                             4 + 8 3 25.0                                                                              a 3 0.0                                                                               a 3 246.3                                                                             b-e                                                                               2 1.703                                                                             a-d                                                                               3 0.00                                                                              b  3 0.00                                                                              b                             8 + 2 3 0.0                                                                               a 3 0.0                                                                               a 3 252.7                                                                             b-e                                                                               3 1.630                                                                             b-d                                                                               3 0.00                                                                              b  3 0.00                                                                              b                             8 + 4 3 0.0                                                                               a 3 0.0                                                                               a 3 273.8                                                                             a-d                                                                               3 1.559                                                                             b-d                                                                               3 0.00                                                                              b  3 0.00                                                                              b                             8 + 8 3 0.0                                                                               a 3 0.0                                                                               a 3 222.7                                                                             e  3 1.736                                                                             a-d                                                                               3 0.00                                                                              b  3 0.00                                                                              b                             A82810 Example No. 39                                                          2 + 2 3 8.3                                                                               a 3 0.0                                                                               a 3 308.4                                                                             a  2 1.487                                                                             b-d                                                                               3 0.00                                                                              b  3 0.22                                                                              b                             2 + 4 3 8.3                                                                               a 3 0.0                                                                               a 3 255.2                                                                             b-e                                                                               2 1.630                                                                             b-d                                                                               3 0.00                                                                              b  3 0.00                                                                              b                             2 + 8 3 8.3                                                                               a 3 0.0                                                                               a 3 213.1                                                                             e  2 1.973                                                                             a  3 0.00                                                                              b  3 0.22                                                                              b                             4 + 2 3 0.0                                                                               a 3 0.0                                                                               a 3 281.3                                                                             a-c                                                                               3 1.556                                                                             b-d                                                                               3 0.00                                                                              b  3 0.00                                                                              b                             4 + 4 3 8.3                                                                               a 3 0.0                                                                               a 3 274.9                                                                             a-d                                                                               2 1.610                                                                             b-d                                                                               3 0.00                                                                              b  3 0.00                                                                              b                             4 + 8 3 0.0                                                                               a 3 0.0                                                                               a 3 230.2                                                                             d-e                                                                               3 1.767                                                                             a-c                                                                               3 0.00                                                                              b  3 0.00                                                                              b                             8 + 2 3 0.0                                                                               a 3 0.0                                                                               a 3 280.8                                                                             a-c                                                                               3 1.589                                                                             b-d                                                                               3 0.00                                                                              b  3 0.00                                                                              b                             8 + 4 3 0.0                                                                               a 3 0.0                                                                               a 3 275.9                                                                             a-d                                                                               3 1.592                                                                             b-d                                                                               3 0.00                                                                              b  3 0.00                                                                              b                             8 + 8 3 8.3                                                                               a 3 0.0                                                                               a 3 213.9                                                                             e  2 1.954                                                                             a  3 0.00                                                                              b  3 0.00                                                                              b                             __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 12                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. maxima                                                                                           Lesion Scores                              Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                               Feed/Gain                                                                              Intestinal                                                                             Cecal                              PPM   # Total %                                                                             # % DTC                                                                               # Mean  # Mean  # Mean  # Mean                             __________________________________________________________________________     NC                                                                             0     3 0.0                                                                               b 3 0.0                                                                               b 3 304.0                                                                             a-b                                                                               3 1.463                                                                             c-d                                                                               3 0.00                                                                              b  3 0.00                                                                              c                             IC                                                                             0     3 33.3                                                                              a 3 33.3                                                                              a 3 161.9                                                                             f          3 7.75                                                                              a  3 3.67                                                                              a                             A82810 + Example No. 113                                                       2 + 2 3 0.0                                                                               b 3 0.0                                                                               b 3 289.5                                                                             a-c                                                                               3 1.569                                                                             b-d                                                                               3 0.75                                                                              b  3 0.33                                                                              c                             2 + 4 3 0.0                                                                               b 3 0.0                                                                               b 3 300.6                                                                             a-b                                                                               3 1.451                                                                             d  3 0.00                                                                              b  3 0.00                                                                              c                             2 + 8 3 0.0                                                                               b 3 0.0                                                                               b 3 254.5                                                                             b-d                                                                               3 1.650                                                                             b-d                                                                               3 0.00                                                                              b  3 0.00                                                                              c                             4 + 2 3 0.0                                                                               b 3 0.0                                                                               b 3 291.4                                                                             a-c                                                                               3 1.481                                                                             c-d                                                                               3 0.00                                                                              b  3 0.00                                                                              c                             4 + 4 3 0.0                                                                               b 3 0.0                                                                               b 3 292.4                                                                             a-c                                                                               3 1.501                                                                             b-d                                                                               3 0.00                                                                              b  3 0.00                                                                              c                             4 + 8 3 0.0                                                                               b 3 0.0                                                                               b 3 258.3                                                                             b-d                                                                               3 1.628                                                                             b-d                                                                               3 0.00                                                                              b  3 0.00                                                                              c                             8 + 2 3 0.0                                                                               b 3 0.0                                                                               b 3 291.7                                                                             a-c                                                                               3 1.506                                                                             b-d                                                                               3 0.17                                                                              b  3 0.00                                                                              c                             8 + 4 3 0.0                                                                               b 3 0.0                                                                               b 3 276.1                                                                             a-c                                                                               3 1.555                                                                             b-d                                                                               3 0.00                                                                              b  3 0.00                                                                              c                             8 + 8 3 0.0                                                                               b 3 0.0                                                                               b 3 253.5                                                                             b-d                                                                               3 1.660                                                                             b-c                                                                               3 0.00                                                                              b  3 0.00                                                                              c                             A82810 + Example No. 39                                                        2 + 2 3 8.3                                                                               b 3 0.0                                                                               b 3 276.6                                                                             a-c                                                                               2 1.596                                                                             b-d                                                                               3 0.56                                                                              b  3 0.72                                                                              b                             2 + 4 3 8.3                                                                               b 3 0.0                                                                               b 3 279.4                                                                             a-c                                                                               2 1.548                                                                             b-d                                                                               3 0.00                                                                              b  3 0.00                                                                              c                             2 + 8 3 8.3                                                                               b 3 0.0                                                                               b 3 228.2                                                                             d-e                                                                               2 1.891                                                                             a  3 0.00                                                                              b  3 0.00                                                                              c                             4 + 2 3 0.0                                                                               b 3 0.0                                                                               b 3 310.9                                                                             a  3 1.462                                                                             c-d                                                                               3 0.00                                                                              b  3 0.00                                                                              c                             4 + 4 3 0.0                                                                               b 3 0.0                                                                               b 3 276.8                                                                             a-c                                                                               3 1.554                                                                             b-d                                                                               3 0.00                                                                              b  3 0.00                                                                              c                             4 + 8 3 0.0                                                                               b 3 0.0                                                                               b 3 245.5                                                                             c-e                                                                               3 1.723                                                                             b  3 0.00                                                                              b  3 0.00                                                                              c                             8 + 2 3 0.0                                                                               b 3 0.0                                                                               b 3 284.5                                                                             a-c                                                                               3 1.540                                                                             b-d                                                                               3 0.00                                                                              b  3 0.00                                                                              c                             8 + 4 3 8.3                                                                               b 3 0.0                                                                               b 3 277.6                                                                             a-c                                                                               2 1.565                                                                             b-d                                                                               3 0.00                                                                              b  3 0.00                                                                              c                             8 + 8 3 16.7                                                                              b 3 0.0                                                                               b 3 213.1                                                                             e  1 1.382                                                                             a-b                                                                               3 0.00                                                                              b  3 0.00                                                                              c                             __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO 13                                                               Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. acervulina                                                                                       Lesion Scores                              Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                               Feed/Gain                                                                              Intestinal                                                                             Cecal                              PPM   # Total %                                                                             # % DTC                                                                               # Mean  # Mean  # Mean  # Mean                             __________________________________________________________________________     NC                                                                             0     3 8.3                                                                               a 3 0.0                                                                               a 3 330.7                                                                             a  2 1.448                                                                             d  3 0.00                                                                              f  3 0.00                                                                              c                             IC                                                                             0     3 0.0                                                                               a 3 0.0                                                                               a 3 250.5                                                                             d  3 1.817                                                                             a  3 7.25                                                                              a  3 3.67                                                                              a                             SALINOMYCIN                                                                    8     3 0.0                                                                               a 3 0.0                                                                               a 3 254.7                                                                             c-d                                                                               3 1.752                                                                             a-c                                                                               3 5.33                                                                              a-c                                                                               3 3.08                                                                              a-b                           16    3 8.3                                                                               a 3 0.0                                                                               a 3 279.6                                                                             b-d                                                                               2 1.620                                                                             a-d                                                                               3 2.97                                                                              c-f                                                                               3 3.72                                                                              a                             32    3 0.0                                                                               a 3 0.0                                                                               a 3 287.0                                                                             b-d                                                                               3 1.604                                                                             b-d                                                                               3 1.83                                                                              d-f                                                                               3 3.25                                                                              a-b                           Example No. 39                                                                 1     3 0.0                                                                               a 3 0.0                                                                               a 3 263.3                                                                             b-d                                                                               3 1.742                                                                             a-c                                                                               3 7.25                                                                              a  3 3.75                                                                              a                             3     3 0.0                                                                               a 3 0.0                                                                               a 3 247.0                                                                             d  3 1.851                                                                             a  3 6.17                                                                              a-b                                                                               3 3.08                                                                              a-b                           5     3 0.0                                                                               a 3 0.0                                                                               a 3 245.3                                                                             d  3 1.791                                                                             a-b                                                                               3 3.92                                                                              b-e                                                                               3 3.50                                                                              a                             SALINOMYCIN + Example No. 39                                                   8 + 1 3 0.0                                                                               a 3 0.0                                                                               a 3 270.3                                                                             b-d                                                                               3 1.706                                                                             a-d                                                                               3 4.42                                                                              b-d                                                                               3 3.75                                                                              a                             8 + 3 3 8.3                                                                               a 3 0.0                                                                               a 3 295.2                                                                             b-d                                                                               2 1.713                                                                             a-d                                                                               3 2.86                                                                              c-f                                                                               3 3.19                                                                              a-b                           8 + 5 3 0.0                                                                               a 3 0.0                                                                               a 3 266.1                                                                             b-d                                                                               3 1.684                                                                             a-d                                                                               3 2.00                                                                              d-f                                                                               3 2.83                                                                              a-b                           16 + 1                                                                               3 8.3                                                                               a 3 0.0                                                                               a 3 273.1                                                                             b-d                                                                               2 1.684                                                                             a-d                                                                               3 2.53                                                                              c-f                                                                               3 3.83                                                                              a                             16 + 3                                                                               3 0.0                                                                               a 3 0.0                                                                               a 3 284.8                                                                             b-d                                                                               3 1.599                                                                             b-d                                                                               3 1.25                                                                              e-f                                                                               3 3.33                                                                              a                             16 + 5                                                                               3 0.0                                                                               a 3 0.0                                                                               a 3 295.8                                                                             a-c                                                                               3 1.559                                                                             b-d                                                                               3 1.00                                                                              e-f                                                                               3 2.92                                                                              a-b                           32 + 1                                                                               3 8.3                                                                               a 3 0.0                                                                               a 3 296.7                                                                             a-c                                                                               2 1.536                                                                             c-d                                                                               3 1.14                                                                              e-f                                                                               3 2.67                                                                              a-b                           32 + 3                                                                               3 0.0                                                                               a 3 0.0                                                                               a 3 303.6                                                                             a-b                                                                               3 1.535                                                                             c-d                                                                               3 0.75                                                                              e-f                                                                               3 1.83                                                                              b                             32 + 5                                                                               3 0.0                                                                               a 3 0.0                                                                               a 3 298.5                                                                             a-c                                                                               3 1.568                                                                             b-d                                                                               3 0.42                                                                              f  3 0.25                                                                              c                             __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO 14                                                               Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                       Lesion Scores                              Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                               Feed/Gain                                                                              Intestinal                                                                             Cecal                              PPM   # Total %                                                                             # % DTC                                                                               # Mean  # Mean  # Mean  # Mean                             __________________________________________________________________________     NC                                                                             0     3 0.0                                                                               a 3 0.0                                                                               a 3 319.9                                                                             a  3 1.403                                                                             c  3 0.00                                                                              d  3 0.00                                                                              e                             IC                                                                             0     3 0.0                                                                               a 3 0.0                                                                               a 3 227.6                                                                             d  3 1.837                                                                             a  3 7.50                                                                              a  3 2.92                                                                              a                             A82810 + Example No. 59                                                        2 + 2 3 0.0                                                                               a 3 0.0                                                                               a 3 262.3                                                                             b-d                                                                               3 1.622                                                                             b-c                                                                               3 4.75                                                                              b  3 2.83                                                                              a                             2 + 4 3 16.7                                                                              a 3 0.0                                                                               a 3 251.8                                                                             c-d                                                                               2 1.609                                                                             b-c                                                                               3 1.33                                                                              c-d                                                                               3 1.58                                                                              b-c                           2 + 8 3 0.0                                                                               a 3 0.0                                                                               a 3 274.6                                                                             a-d                                                                               3 1.552                                                                             b-c                                                                               3 0.00                                                                              d  3 0.75                                                                              c-e                           4 + 2 3 0.0                                                                               a 3 0.0                                                                               a 3 288.7                                                                             a-c                                                                               3 1.473                                                                             b-c                                                                               3 0.83                                                                              c-d                                                                               3 1.42                                                                              b-d                           4 + 4 3 0.0                                                                               a 3 0.0                                                                               a 3 278.9                                                                             a-c                                                                               3 1.486                                                                             b-c                                                                               3 0.33                                                                              d  3 1.50                                                                              b-c                           4 + 8 3 8.3                                                                               a 3 0.0                                                                               a 3 279.3                                                                             a-c                                                                               2 1.573                                                                             b-c                                                                               3 0.00                                                                              d  3 0.25                                                                              d-e                           8 + 2 3 0.0                                                                               a 3 0.0                                                                               a 3 304.1                                                                             a-c                                                                               3 1.419                                                                             c  3 0.00                                                                              d  3 0.17                                                                              d-e                           8 + 4 3 0.0                                                                               a 3 0.0                                                                               a 3 289.2                                                                             a-c                                                                               3 1.483                                                                             b-c                                                                               3 0.00                                                                              d  3 0.17                                                                              d-e                           8 + 8 3 25.0                                                                              a 3 0.0                                                                               a 3 269.2                                                                             a-d                                                                               1 1.541                                                                             b-c                                                                               3 0.00                                                                              d  3 0.00                                                                              e                             A82810 + Example No. 56                                                        2 + 2 3 0.0                                                                               a 3 0.0                                                                               a 3 252.2                                                                             c-d                                                                               3 1.667                                                                             b  3 5.00                                                                              b  3 3.25                                                                              a                             2 + 4 3 0.0                                                                               a 3 0.0                                                                               a 3 284.3                                                                             a-c                                                                               3 1.541                                                                             b-c                                                                               3 2.33                                                                              c  3 2.33                                                                              a-b                           2 + 8 3 0.0                                                                               a 3 0.0                                                                               a 3 264.8                                                                             b-d                                                                               3 1.587                                                                             b-c                                                                               3 0.42                                                                              d  3 1.00                                                                              c-e                           4 + 2 3 0.0                                                                               a 3 0.0                                                                               a 3 312.1                                                                             a-b                                                                               3 1.447                                                                             b-c                                                                               3 0.75                                                                              c-d                                                                               3 0.67                                                                              c-e                           4 + 4 3 0.0                                                                               a 3 0.0                                                                               a 3 295.0                                                                             a-c                                                                               3 1.460                                                                             b-c                                                                               3 0.33                                                                              d  3 1.25                                                                              b-e                           4 + 8 3 0.0                                                                               a 3 0.0                                                                               a 3 286.3                                                                             a-c                                                                               3 1.536                                                                             b-c                                                                               3 0.00                                                                              d  3 0.58                                                                              c-e                           8 + 2 3 0.0                                                                               a 3 0.0                                                                               a 3 296.8                                                                             a-c                                                                               3 1.477                                                                             b-c                                                                               3 0.00                                                                              d  3 0.25                                                                              d-e                           8 + 4 3 0.0                                                                               a 3 0.0                                                                               a 3 294.8                                                                             a-c                                                                               3 1.530                                                                             b-c                                                                               3 0.00                                                                              d  3 0.17                                                                              d-e                           8 + 8 3 0.0                                                                               a 3 0.0                                                                               a 3 263.6                                                                             b-d                                                                               3 1.577                                                                             b-c                                                                               3 0.00                                                                              d  3 0.00                                                                              e                             __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 15                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. maxima and E. tenella                                                                                           Lesion Scores                              Treatment                                                                            Mortality Mean                                                                               Wt. Gain                                                                               Feed/Gain                                                                              Intestinal                                                                             Cecal                              PPM   # Total %                                                                             # % DTC                                                                               # Mean  # Mean  # Mean  # Mean                             __________________________________________________________________________     NC                                                                             0     3 0.0                                                                               b 3 0.0                                                                               b 3 300.7                                                                             a  3 1.480                                                                             a  3 0.00                                                                              b  3 0.00                                                                              d                             IC                                                                             0     3 33.3                                                                              a 3 33.3                                                                              a 3 170.6                                                                             b          3 8.17                                                                              a  3 3.50                                                                              a                             A82810 + Example No. 57                                                        2 + 2 3 0.0                                                                               b 3 0.0                                                                               b 3 260.2                                                                             a  3 1.617                                                                             a  3 7.33                                                                              a  3 2.92                                                                              a-b                           2 + 4 3 0.0                                                                               b 3 0.0                                                                               b 3 291.5                                                                             a  3 1.484                                                                             a  3 2.50                                                                              b  3 1.50                                                                              c-d                           2 + 8 3 0.0                                                                               b 3 0.0                                                                               b 3 259.8                                                                             a  3 1.621                                                                             a  3 1.50                                                                              b  3 1.08                                                                              c-d                           4 + 2 3 0.0                                                                               b 3 0.0                                                                               b 3 285.3                                                                             a  3 1.575                                                                             a  3 6.00                                                                              a  3 2.25                                                                              b-c                           4 + 4 3 0.0                                                                               b 3 0.0                                                                               b 3 277.3                                                                             a  3 1.501                                                                             a  3 0.75                                                                              b  3 0.42                                                                              d                             4 + 8 3 0.0                                                                               b 3 0.0                                                                               b 3 262.2                                                                             a  3 1.576                                                                             a  3 0.00                                                                              b  3 0.00                                                                              d                             8 + 2 3 0.0                                                                               b 3 0.0                                                                               b 3 298.1                                                                             a  3 1.424                                                                             a  3 0.33                                                                              b  3 0.08                                                                              d                             8 + 4 3 0.0                                                                               b 3 0.0                                                                               b 3 293.8                                                                             a  3 1.474                                                                             a  3 0.00                                                                              b  3 0.00                                                                              d                             8 + 8 3 8.3                                                                               b 3 0.0                                                                               b 3 264.4                                                                             a  2 1.514                                                                             a  3 0.00                                                                              b  3 0.00                                                                              d                             A82810 + Example No. 56                                                        2 + 2 3 0.0                                                                               b 3 0.0                                                                               b 3 259.8                                                                             a  3 1.626                                                                             a  3 8.67                                                                              a  3 3.58                                                                              a                             2 + 4 3 16.7                                                                              b 3 0.0                                                                               b 3 300.2                                                                             a  1 1.449                                                                             a  3 3.56                                                                              b  3 2.31                                                                              b-c                           2 + 8 3 0.0                                                                               b 3 0.0                                                                               b 3 289.1                                                                             a  3 1.442                                                                             a  3 0.00                                                                              b  3 0.33                                                                              d                             4 + 2 3 0.0                                                                               b 3 0.0                                                                               b 3 282.5                                                                             a  3 1.475                                                                             a  3 7.42                                                                              a  3 2.17                                                                              b-c                           4 + 4 3 0.0                                                                               b 3 0.0                                                                               b 3 302.9                                                                             a  3 1.420                                                                             a  3 0.75                                                                              b  3 0.83                                                                              d                             4 + 8 3 0.0                                                                               b 3 0.0                                                                               b 3 286.3                                                                             a  3 1.516                                                                             a  3 1.50                                                                              b  3 0.25                                                                              d                             8 + 2 3 8.3                                                                               b 3 0.0                                                                               b 3 298.6                                                                             a  2 1.451                                                                             a  3 0.00                                                                              b  3 0.00                                                                              d                             8 + 4 3 0.0                                                                               b 3 0.0                                                                               b 3 293.2                                                                             a  3 1.476                                                                             a  3 0.00                                                                              b  3 0.00                                                                              d                             8 + 8 3 0.0                                                                               b 3 0.0                                                                               b 3 279.2                                                                             a  3 1.525                                                                             a  3 0.00                                                                              b  3 0.17                                                                              d                             __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 16                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. acervulina                                                                                         Lesion Scores                            Treatment                                                                            Mortality Mean  Wt. Gain                                                                               Feed/Gain                                                                              Intestinal                                                                             Cecal                            PPM   # Total %                                                                              # % DTC # Mean  # Mean  # Mean  # Mean                           __________________________________________________________________________     NC                                                                             0     3 0.0                                                                               e  3 0.0                                                                               e  3 299.3                                                                             a  3 1.539                                                                             d  3 0.00                                                                              c  3 0.00                                                                              e                           IC                                                                             0     3 16.7                                                                              a-e                                                                               3 8.3                                                                               a-e                                                                               3 199.4                                                                             e-j                                                                               1 2.069                                                                             a-d                                                                               3 8.81                                                                              a  3 3.11                                                                              a-c                         A204                                                                           2     3 8.3                                                                               a-e                                                                               3 8.3                                                                               a-e                                                                               3 190.3                                                                             f-j                                                                               2 2.427                                                                             a  3 7.00                                                                              a-b                                                                               3 3.58                                                                              a                           4     3 0.0                                                                               e  3 0.0                                                                               e  3 215.1                                                                             c-i                                                                               3 1.936                                                                             a-d                                                                               3 8.00                                                                              a-b                                                                               3 3.58                                                                              a                           6     3 25.0                                                                              a-c                                                                               3 16.7                                                                              a-d                                                                               3 152.5                                                                             j  1 2.215                                                                             a-b                                                                               3 7.06                                                                              a-b                                                                               3 3.75                                                                              a                           8     3 8.3                                                                               a-e                                                                               3 8.3                                                                               a-e                                                                               3 181.6                                                                             h-j                                                                               2 2.044                                                                             a-d                                                                               3 7.58                                                                              a-b                                                                               3 3.50                                                                              a                           Example No. 56                                                                 2     3 33.3                                                                              a  3 25.0                                                                              a-b                                                                               3 178.0                                                                             i-j        3 7.53                                                                              a-b                                                                               3 3.75                                                                              a                           4     3 8.3                                                                               a-e                                                                               3 0.0                                                                               e  3 175.0                                                                             i-j                                                                               2 2.124                                                                             a-d                                                                               3 6.83                                                                              a-b                                                                               3 3.36                                                                              a-b                         6     3 25.0                                                                              a-c                                                                               3 25.0                                                                              a-b                                                                               3 206.7                                                                             d-i                                                                               1 2.110                                                                             a-d                                                                               3 6.33                                                                              a-b                                                                               3 3.67                                                                              a                           8     3 16.7                                                                              a-e                                                                               3 16.7                                                                              a-d                                                                               3 200.6                                                                             e-j                                                                               1 2.095                                                                             a-d                                                                               3 1.75                                                                              c  3 3.75                                                                              a                           A204 + Example No. 56                                                          2 + 2 3 8.3                                                                               a-e                                                                               3 0.0                                                                               e  3 188.1                                                                             g-j                                                                               2 2.128                                                                             a-d                                                                               3 8.06                                                                              a-b                                                                               3 3.36                                                                              a-b                         2 + 4 3 0.0                                                                               e  3 0.0                                                                               e  3 222.4                                                                             b-i                                                                               3 2.003                                                                             a-d                                                                               3 7.17                                                                              a-b                                                                               3 3.42                                                                              a-b                         2 + 6 3 16.7                                                                              a-e                                                                               3 0.0                                                                               e  3 216.2                                                                             c-i                                                                               1 2.152                                                                             a-c                                                                               3 6.31                                                                              a-b                                                                               3 3.61                                                                              a                           2 + 8 3 0.0                                                                               e  3 0.0                                                                               e  3 240.9                                                                             b-g                                                                               3 1.834                                                                             a-d                                                                               3 0.00                                                                              c  3 2.42                                                                              a-d                         4 + 2 3 16.7                                                                              a-e                                                                               3 8.3                                                                               a-e                                                                               3 184.8                                                                             h-j                                                                               1 2.056                                                                             a-d                                                                               3 7.42                                                                              a-b                                                                               3 3.72                                                                              a                           4 + 4 3 0.0                                                                               e  3 0.0                                                                               e  3 233.4                                                                             b-h                                                                               3 1.855                                                                             a-d                                                                               3 5.92                                                                              a-b                                                                               3 3.92                                                                              a                           4 + 6 3 8.3                                                                               a-e                                                                               3 8.3                                                                               a-e                                                                               3 240.7                                                                             b-g                                                                               2 2.050                                                                             a-d                                                                               3 0.50                                                                              c  3 2.75                                                                              a-d                         4 + 8 3 0.0                                                                               e  3 0.0                                                                               e  3 253.8                                                                             a-e                                                                               3 1.715                                                                             b-d                                                                               3 0.00                                                                              c  3 1.75                                                                              b-d                         6 + 2 3 16.7                                                                              a-e                                                                               3 8.3                                                                               a-e                                                                               3 261.3                                                                             a-d                                                                               2 1.764                                                                             a-d                                                                               3 7.11                                                                              a-b                                                                               3 3.67                                                                              a                           6 + 4 3 8.3                                                                               a-e                                                                               3 8.3                                                                               a-e                                                                               3 247.8                                                                             b-e                                                                               2 1.874                                                                             a-d                                                                               3 1.25                                                                              c  3 2.67                                                                              a-d                         6 + 6 3 0.0                                                                               e  3 0.0                                                                               e  3 263.8                                                                             a-c                                                                               3 1.716                                                                             b-d                                                                               3 0.00                                                                              c  3 1.25                                                                              d-e                         6 + 8 3 0.0                                                                               e  3 0.0                                                                               e  3 262.5                                                                             a-d                                                                               3 1.734                                                                             b-d                                                                               3 0.00                                                                              c  3 1.25                                                                              d-e                         8 + 2 3 8.3                                                                               a-e                                                                               3 0.0                                                                               e  3 244.7                                                                             b-f                                                                               2 1.927                                                                             a-d                                                                               3 3.78                                                                              b-c                                                                               3 3.36                                                                              a-b                         8 + 4 3 8.3                                                                               a-e                                                                               3 0.0                                                                               e  3 271.4                                                                             a-c                                                                               2 1.812                                                                             a-d                                                                               3 2.50                                                                              c  3 3.25                                                                              a-b                         8 + 6 3 0.0                                                                               e  3 0.0                                                                               e  3 273.8                                                                             a-b                                                                               3 1.623                                                                             c-d                                                                               3 0.00                                                                              c  3 1.67                                                                              c-d                         8 + 8 3 0.0                                                                               e  3 0.0                                                                               e  3 240.4                                                                             b-g                                                                               3 1.924                                                                             a-d                                                                               3 0.00                                                                              c  3 1.17                                                                              d-e                         __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 17                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. maxima and E. tenella                                                                                             Lesion Scores                            Treatment                                                                            Mortality Mean  Wt. Gain                                                                               Feed/Gain                                                                              Intestinal                                                                             Cecal                            PPM   # Total %                                                                              # % DTC # Mean  # Mean  # Mean  # Mean                           __________________________________________________________________________     NC                                                                             0     3 8.3                                                                               a-e                                                                               3 0.0                                                                               e  3 320.3                                                                             a  2 1.463                                                                             e  3 0.67                                                                              f  3 0.17                                                                              f                           IC                                                                             0     3 8.3                                                                               a-e                                                                               3 0.0                                                                               e  3 205.9                                                                             d-e                                                                               2 2.041                                                                             a-d                                                                               3 8.72                                                                              a  3 3.56                                                                              a-b                         A204                                                                           2     3 0.0                                                                               e  3 0.0                                                                               e  3 184.3                                                                             e  3 2.159                                                                             a-b                                                                               3 9.08                                                                              a  3 3.67                                                                              a-b                         4     3 8.3                                                                               a-e                                                                               3 8.3                                                                               a-e                                                                               3 225.5                                                                             b-e                                                                               2 1.857                                                                             a-e                                                                               3 8.17                                                                              a  3 3.92                                                                              a                           6     3 8.3                                                                               a-e                                                                               3 8.3                                                                               a-e                                                                               3 220.1                                                                             c-e                                                                               2 2.108                                                                             a-c                                                                               3 7.75                                                                              a  3 3.67                                                                              a-b                         8     3 0.0                                                                               e  3 0.0                                                                               e  3 255.1                                                                             a-d                                                                               3 1.751                                                                             a-e                                                                               3 9.00                                                                              a  3 3.33                                                                              a-b                         Example No. 56                                                                 2     3 0.0                                                                               e  3 0.0                                                                               e  3 207.8                                                                             d-e                                                                               3 1.929                                                                             a-e                                                                               3 8.83                                                                              a  3 3.58                                                                              a-b                         4     3 8.3                                                                               a-e                                                                               3 0.0                                                                               e  3 206.3                                                                             d-e                                                                               2 2.087                                                                             a-d                                                                               3 8.58                                                                              a  3 3.50                                                                              a-b                         6     3 0.0                                                                               e  3 0.0                                                                               e  3 203.1                                                                             d-e                                                                               3 2.192                                                                             a  3 8.42                                                                              a  3 3.67                                                                              a-b                         8     3 0.0                                                                               e  3 0.0                                                                               e  3 232.8                                                                             b-e                                                                               3 1.881                                                                             a-e                                                                               3 6.83                                                                              a-b                                                                               3 3.50                                                                              a-b                         A204 + Example No. 56                                                          2 + 2 3 0.0                                                                               e  3 0.0                                                                               e  3 235.0                                                                             b-e                                                                               3 1.955                                                                             a-d                                                                               3 8.67                                                                              a  3 3.00                                                                              a-b                         2 + 4 3 0.0                                                                               e  3 0.0                                                                               e  3 250.7                                                                             b-e                                                                               3 1.818                                                                             a-e                                                                               3 8.50                                                                              a  3 3.50                                                                              a-b                         2 + 6 3 8.3                                                                               a-e                                                                               3 8.3                                                                               a-e                                                                               3 255.3                                                                             a-d                                                                               2 1.743                                                                             b-e                                                                               3 6.50                                                                              a-c                                                                               3 3.67                                                                              a-b                         2 + 8 3 0.0                                                                               e  3 0.0                                                                               e  3 246.3                                                                             b-e                                                                               3 1.837                                                                             a-e                                                                               3 3.17                                                                              d-f                                                                               3 1.83                                                                              c-d                         4 + 2 3 8.3                                                                               a-e                                                                               3 8.3                                                                               a-e                                                                               3 236.7                                                                             b-e                                                                               2 1.801                                                                             a-e                                                                               3 8.17                                                                              a  3 3.58                                                                              a-b                         4 + 4 3 0.0                                                                               e  3 0.0                                                                               e  3 268.0                                                                             a-d                                                                               3 1.743                                                                             b-e                                                                               3 7.92                                                                              a  3 3.08                                                                              a-b                         4 + 6 3 0.0                                                                               e  3 0.0                                                                               e  3 269.4                                                                             a-d                                                                               3 1.728                                                                             b-e                                                                               3 4.08                                                                              b-e                                                                               3 2.17                                                                              b-d                         4 + 8 3 0.0                                                                               e  3 0.0                                                                               e  3 266.0                                                                             a-d                                                                               3 1.804                                                                             a-e                                                                               3 1.08                                                                              e-f                                                                               3 0.33                                                                              e-f                         6 + 2 3 0.0                                                                               e  3 0.0                                                                               e  3 247.5                                                                             b-e                                                                               3 1.843                                                                             a-e                                                                               3 7.58                                                                              a  3 3.25                                                                              a-b                         6 + 4 3 8.3                                                                               a-e                                                                               3 8.3                                                                               a-e                                                                               3 281.1                                                                             a-c                                                                               2 1.685                                                                             b-e                                                                               3 4.33                                                                              b-e                                                                               3 2.75                                                                              a-c                         6 + 6 3 0.0                                                                               e  3 0.0                                                                               e  3 297.8                                                                             a-b                                                                               3 1.635                                                                             d-e                                                                               3 1.58                                                                              e-f                                                                               3 1.50                                                                              d-e                         6 + 8 3 0.0                                                                               e  3 0.0                                                                               e  3 273.3                                                                             a-d                                                                               3 1.708                                                                             b-e                                                                               3 0.50                                                                              f  3 0.50                                                                              e-f                         8 + 2 3 0.0                                                                               e  3 0.0                                                                               e  3 268.0                                                                             a-d                                                                               3 1.757                                                                             a-e                                                                               3 5.92                                                                              a-d                                                                               3 3.83                                                                              a                           8 + 4 3 0.0                                                                               e  3 0.0                                                                               e  3 281.8                                                                             a-c                                                                               3 1.636                                                                             c-e                                                                               3 3.42                                                                              c-f                                                                               3 3.42                                                                              a-b                         8 + 6 3 8.3                                                                               a-e                                                                               3 0.0                                                                               e  3 274.6                                                                             a-d                                                                               2 1.634                                                                             d-e                                                                               3 0.00                                                                              f  3 0.50                                                                              e-f                         8 + 8 3 0.0                                                                               e  3 0.0                                                                               e  3 267.4                                                                             a-d                                                                               3 1.758                                                                             a-e                                                                               3 0.00                                                                              f  3 0.33                                                                              e-f                         __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 18                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                         Lesion Scores                            Treatment                                                                            Mortality Mean  Wt. Gain                                                                               Feed/Gain                                                                              Intestinal                                                                             Cecal                            PPM   # Total %                                                                              # % DTC # Mean  # Mean  # Mean  # Mean                           __________________________________________________________________________     NC                                                                             0     3 0.0                                                                               e  3 0.0                                                                               e  3 308.7                                                                             a  3 1.488                                                                             c  3 0.00                                                                              g  3 0.00                                                                              d                           IC                                                                             0     3 0.0                                                                               e  3 0.0                                                                               e  3 224.2                                                                             b-e                                                                               3 1.956                                                                             a-c                                                                               3 7.92                                                                              a-b                                                                               3 3.67                                                                              a-b                         NARASIN                                                                        10    3 33.3                                                                              a  3 33.3                                                                              a  3 235.9                                                                             b-e        3 7.17                                                                              a-c                                                                               3 3.67                                                                              a-b                         20    3 16.7                                                                              a-e                                                                               3 8.3                                                                               a-e                                                                               3 194.3                                                                             d-e                                                                               1 2.162                                                                             a-b                                                                               3 6.03                                                                              a-e                                                                               3 3.64                                                                              a-b                         30    3 25.0                                                                              a-c                                                                               3 25.0                                                                              a-c                                                                               3 208.6                                                                             c-e                                                                               1 1.819                                                                             a-c                                                                               3 4.67                                                                              b-f                                                                               3 3.83                                                                              a-b                         40    3 16.7                                                                              a-e                                                                               3 16.7                                                                              a-e                                                                               3 218.5                                                                             b-e                                                                               1 1.959                                                                             a-c                                                                               3 4.50                                                                              b-f                                                                               3 3.92                                                                              a                           Example No. 56                                                                 2     3 16.7                                                                              a-e                                                                               3 16.7                                                                              a-e                                                                               3 188.3                                                                             e  1 2.049                                                                             a-c                                                                               3 8.58                                                                              a  3 3.75                                                                              a-b                         4     3 25.0                                                                              a-c                                                                               3 25.0                                                                              a-c                                                                               3 219.3                                                                             b-e        3 7.06                                                                              a-d                                                                               3 3.69                                                                              a-b                         6     3 0.0                                                                               e  3 0.0                                                                               e  3 193.4                                                                             d-e                                                                               3 2.193                                                                             a  3 5.67                                                                              a-e                                                                               3 3.42                                                                              a-b                         8     3 8.3                                                                               a-e                                                                               3 0.0                                                                               e  3 220.5                                                                             b-e                                                                               2 2.025                                                                             a-c                                                                               3 1.33                                                                              f-g                                                                               3 2.89                                                                              a-b                         NARASIN + Example No. 56                                                       10 + 2                                                                               3 8.3                                                                               a-e                                                                               3 8.3                                                                               a-e                                                                               3 224.3                                                                             b-e                                                                               2 2.044                                                                             a-c                                                                               3 6.00                                                                              a-e                                                                               3 3.58                                                                              a-b                         10 + 4                                                                               3 8.3                                                                               a-e                                                                               3 0.0                                                                               e  3 224.4                                                                             b-e                                                                               2 1.852                                                                             a-c                                                                               3 2.14                                                                              e-g                                                                               3 3.56                                                                              a-b                         10 + 6                                                                               3 8.3                                                                               a-e                                                                               3 8.3                                                                               a-e                                                                               3 221.8                                                                             b-e                                                                               2 1.893                                                                             a-c                                                                               3 3.42                                                                              c-g                                                                               3 3.67                                                                              a-b                         10 + 8                                                                               3 16.7                                                                              a-e                                                                               3 16.7                                                                              a-e                                                                               3 252.3                                                                             b-d                                                                               1 1.727                                                                             a-c                                                                               3 0.92                                                                              f-g                                                                               3 3.58                                                                              a-b                         20 + 2                                                                               3 0.0                                                                               e  3 0.0                                                                               e  3 225.9                                                                             b-e                                                                               3 1.907                                                                             a-c                                                                               3 3.33                                                                              c-g                                                                               3 3.42                                                                              a-b                         20 + 4                                                                               3 0.0                                                                               e  3 0.0                                                                               e  3 239.2                                                                             b-e                                                                               3 1.819                                                                             a-c                                                                               3 3.17                                                                              d-g                                                                               3 3.33                                                                              a-b                         20 + 6                                                                               3 0.0                                                                               e  3 0.0                                                                               e  3 264.0                                                                             a-c                                                                               3 1.659                                                                             b-c                                                                               3 1.17                                                                              f-g                                                                               3 3.00                                                                              a-b                         20 + 8                                                                               3 0.0                                                                               e  3 0.0                                                                               e  3 263.4                                                                             a-c                                                                               3 1.691                                                                             b-c                                                                               3 0.00                                                                              g  3 2.75                                                                              b                           30 + 2                                                                               3 8.3                                                                               a-e                                                                               3 8.3                                                                               a-e                                                                               3 208.4                                                                             c-e                                                                               2 1.859                                                                             a-c                                                                               3 4.92                                                                              a-f                                                                               3 3.67                                                                              a-b                         30 + 4                                                                               3 0.0                                                                               e  3 0.0                                                                               e  3 264.6                                                                             a-c                                                                               3 1.732                                                                             a-c                                                                               3 1.42                                                                              f-g                                                                               3 3.75                                                                              a-b                         30 + 6                                                                               3 0.0                                                                               e  3 0.0                                                                               e  3 263.4                                                                             a-c                                                                               3 1.734                                                                             a-c                                                                               3 0.25                                                                              g  3 2.75                                                                              b                           30 + 8                                                                               3 8.3                                                                               a-e                                                                               3 0.0                                                                               e  3 249.9                                                                             b-d                                                                               2 1.690                                                                             b-c                                                                               3 0.00                                                                              g  3 1.56                                                                              c                           40 + 2                                                                               3 0.0                                                                               e  3 0.0                                                                               e  3 246.1                                                                             b-e                                                                               3 1.736                                                                             a-c                                                                               3 2.17                                                                              e-g                                                                               3 3.67                                                                              a-b                         40 + 4                                                                               3 0.0                                                                               e  3 0.0                                                                               e  3 270.1                                                                             a-b                                                                               3 1.643                                                                             b-c                                                                               3 0.92                                                                              f-g                                                                               3 3.25                                                                              a-b                         40 + 6                                                                               3 0.0                                                                               e  3 0.0                                                                               e  3 240.0                                                                             b-e                                                                               3 1.861                                                                             a-c                                                                               3 0.00                                                                              g  3 3.42                                                                              a-b                         40 + 8                                                                               3 8.3                                                                               a-e                                                                               3 0.0                                                                               e  3 261.2                                                                             a-c                                                                               2 1.804                                                                             a-c                                                                               3 0.00                                                                              g  3 1.44                                                                              c                           __________________________________________________________________________

                                      EXPERIMENT NO. 19                            __________________________________________________________________________     Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of                                          broiler cockerels inoculated with E. maxima and E. tenella                                                                 Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 0.0  e  3 0.0  e  3 313.9                                                                              a  3 1.422                                                                              d  3 0.00                                                                               f  3 0.00                                                                               d                   IC                                                                             0     3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 202.3                                                                              c-e                                                                               2 1.791                                                                              a-d                                                                               3 9.00                                                                               a  3 3.67                                                                               a-b                 NARASIN                                                                        10    3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 240.9                                                                              a-e                                                                               2 1.803                                                                              a-d                                                                               3 7.92                                                                               a-b                                                                               3 3.75                                                                               a-b                 20    3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 215.7                                                                              b-e                                                                               2 1.946                                                                              a-c                                                                               3 7.83                                                                               a-b                                                                               3 3.50                                                                               a-b                 30    3 0.0  e  3 0.0  e  3 227.8                                                                              b-e                                                                               3 1.778                                                                              b-d                                                                               3 7.92                                                                               a-b                                                                               3 3.92                                                                               a-b                 40    3 8.3  a-e                                                                               3 0.0  e  3 218.6                                                                              b-e                                                                               2 1.694                                                                              b-d                                                                               3 8.28                                                                               a-b                                                                               3 3.69                                                                               a-b                 Example                                                                        No. 56                                                                         2     3 8.3  a-e                                                                               3 0.0  e  3 190.3                                                                              d-e                                                                               2 2.030                                                                              a-b                                                                               3 8.67                                                                               a-b                                                                               3 3.72                                                                               a-b                 4     3 0.0  e  3 0.0  e  3 190.2                                                                              e  3 2.107                                                                              a  3 8.42                                                                               a-b                                                                               3 3.75                                                                               a-b                 6     2 37.5 a  2 25.0 a  2 236.5                                                                              a-e         2 8.88                                                                               a-b                                                                               2 3.88                                                                               a-b                 8     3 0.0  e  3 0.0  e  3 224.0                                                                              b-e                                                                               3 1.922                                                                              a-c                                                                               3 8.00                                                                               a-b                                                                               3 3.83                                                                               a-b                 NARA-                                                                          SIN +                                                                          Example                                                                        No. 56                                                                         10 + 2                                                                               3 16.7 a-b                                                                               3 8.3  a-e                                                                               3 206.9                                                                              b-e                                                                               2 1.987                                                                              a-c                                                                               3 9.00                                                                               a  3 3.92                                                                               a-b                 10 + 4                                                                               3 0.0  e  3 0.0  e  3 244.0                                                                              a-e                                                                               3 1.699                                                                              b-d                                                                               3 6.83                                                                               a-b                                                                               3 3.50                                                                               a-b                 10 + 6                                                                               3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 250.6                                                                              a-e                                                                               2 1.704                                                                              b-d                                                                               3 5.25                                                                               a-d                                                                               3 3.92                                                                               a-b                 10 + 8                                                                               3 0.0  e  3 0.0  e  3 232.8                                                                              b-e                                                                               3 1.772                                                                              b-d                                                                               3 4.17                                                                               b-e                                                                               3 2.75                                                                               a-c                 20 + 2                                                                               3 8.3  a-e                                                                               3 0.0  e  3 203.5                                                                              b-e                                                                               2 1.783                                                                              a-d                                                                               3 8.92                                                                               a  3 3.83                                                                               a-b                 20 + 4                                                                               3 8.3  a-e                                                                               3 0.0  e  3 268.1                                                                              a-e                                                                               2 1.623                                                                              b-d                                                                               3 6.78                                                                               a-b                                                                               3 3.64                                                                               a-b                 20 + 6                                                                               3 0.0  e  3 0.0  e  3 267.2                                                                              a-e                                                                               3 1.615                                                                              c-d                                                                               3 4.17                                                                               b-e                                                                               3 3.50                                                                               a-b                 20 + 8                                                                               3 8.3  a-e                                                                               3 0.0  e  3 258.1                                                                              a-e                                                                               2 1.801                                                                              a-d                                                                               3 1.17                                                                               e-f                                                                               3 2.56                                                                               a-c                 30 + 2                                                                               3 8.3  a-e                                                                               3 0.0  e  3 229.6                                                                              b-e                                                                               2 1.746                                                                              b-d                                                                               3 8.72                                                                               a-b                                                                               3 3.75                                                                               a-b                 30 + 4                                                                               3 0.0  e  3 0.0  e  3 267.9                                                                              a-e                                                                               3 1.601                                                                              c-d                                                                               3 6.42                                                                               a-c                                                                               3 3.75                                                                               a-b                 30 + 6                                                                               3 0.0  e  3 0.0  e  3 270.9                                                                              a-e                                                                               3 1.612                                                                              c-d                                                                               3 2.00                                                                               d-f                                                                               3 2.83                                                                               a-c                 30 + 8                                                                               3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 278.4                                                                              a-b                                                                               2 1.570                                                                              c-d                                                                               3 0.92                                                                               e-f                                                                               3 2.17                                                                               c                   40 + 2                                                                               3 8.3  a-e                                                                               3 0.0  e  3 268.0                                                                              a-e                                                                               2 1.616                                                                              b-d                                                                               3 5.42                                                                               a-d                                                                               3 3.39                                                                               a-b                 40 + 4                                                                               3 0.0  e  3 0.0  e  3 265.5                                                                              a-e                                                                               3 1.547                                                                              d  3 3.00                                                                               c-f                                                                               3 3.25                                                                               a-c                 40 + 6                                                                               3 0.0  e  3 0.0  e  3 276.0                                                                              a-c                                                                               3 1.621                                                                              b-d                                                                               3 0.00                                                                               f  3 2.42                                                                               b-c                 40 + 8                                                                               3 8.3  a-e                                                                               3 0.0  e  3 271.1                                                                              a-d                                                                               2 1.580                                                                              c-d                                                                               3 0.00                                                                               f  3 0.67                                                                               d                   __________________________________________________________________________

                                      EXPERIMENT NO. 20                            __________________________________________________________________________     Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of                                          broiler cockerels inoculated with E. tenella and E. acervulina                                                             Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 0.0  e  3 0.0  e  3 287.3                                                                              a  3 1.598                                                                              d  3 0.00                                                                               e  3 0.00                                                                               e                   IC                                                                             0     3 8.3  a-e                                                                               3 0.0  e  3 216.7                                                                              c-e                                                                               2 1.855                                                                              a-d                                                                               3 5.42                                                                               a-c                                                                               3 3.92                                                                               a-d                 NARASIN                                                                        10    3 16.7 a-c                                                                               3 0.0  e  3 221.0                                                                              b-e                                                                               1 2.028                                                                              a  3 4.28                                                                               a-d                                                                               3 4.00                                                                               a-d                 20    3 8.3  a-e                                                                               3 0.0  e  3 234.3                                                                              a-e                                                                               2 1.963                                                                              a-c                                                                               3 2.83                                                                               a-e                                                                               3 3.92                                                                               a-d                 30    3 8.3  a-e                                                                               3 0.0  e  3 250.4                                                                              a-d                                                                               2 1.849                                                                              a-d                                                                               3 2.86                                                                               a-e                                                                               3 3.64                                                                               a-d                 40    3 0.0  e  3 0.0  e  3 219.5                                                                              b-e                                                                               3 1.773                                                                              a-d                                                                               3 1.42                                                                               d-e                                                                               3 3.50                                                                               a-d                 Example                                                                        No. 56                                                                         2     3 25.0 a  3 16.7 a  3 213.1                                                                              e           3 6.06                                                                               a  3 3.92                                                                               a-d                 4     3 0.0  e  3 0.0  e  3 218.8                                                                              b-e                                                                               3 2.014                                                                              a-b                                                                               3 5.67                                                                               a-b                                                                               3 4.00                                                                               a-d                 6     3 0.0  e  3 0.0  e  3 214.4                                                                              d-e                                                                               3 1.969                                                                              a-c                                                                               3 2.08                                                                               b-e                                                                               3 3.83                                                                               a-d                 8     3 0.0  e  3 0.0  e  3 225.8                                                                              b-e                                                                               3 1.990                                                                              a-c                                                                               3 0.75                                                                               d-e                                                                               3 3.17                                                                               b-d                 NARA-                                                                          SIN +                                                                          Example                                                                        No. 56                                                                         10 + 2                                                                               3 8.3  a-e                                                                               3 0.0  e  3 220.2                                                                              b-e                                                                               2 1.954                                                                              a-c                                                                               3 2.50                                                                               b-e                                                                               3 4.00                                                                               a-d                 10 + 4                                                                               3 0.0  e  3 0.0  e  3 241.5                                                                              a-e                                                                               3 1.850                                                                              a-d                                                                               3 2.33                                                                               b-e                                                                               3 3.67                                                                               a-d                 10 + 6                                                                               3 8.3  a-e                                                                               3 8.3  a-c                                                                               3 248.2                                                                              a-e                                                                               2 1.808                                                                              a-d                                                                               3 1.75                                                                               c-e                                                                               3 4.00                                                                               a-d                 10 + 8                                                                               3 0.0  e  3 0.0  e  3 239.8                                                                              a-e                                                                               3 1.862                                                                              a-d                                                                               3 0.42                                                                               d-e                                                                               3 2.92                                                                               d                   20 + 2                                                                               3 0.0  e  3 0.0  e  3 244.3                                                                              a-e                                                                               3 1.905                                                                              a-d                                                                               3 2.67                                                                               a-e                                                                               3 3.58                                                                               a-d                 20 + 4                                                                               3 8.3  a-e                                                                               3 0.0  e  3 240.4                                                                              a-e                                                                               2 1.923                                                                              a-d                                                                               3 2.69                                                                               a-e                                                                               3 3.78                                                                               a-d                 20 + 6                                                                               3 0.0  e  3 0.0  e  3 241.1                                                                              a-e                                                                               3 1.824                                                                              a-d                                                                               3 0.83                                                                               d-e                                                                               3 3.75                                                                               a-d                 20 + 8                                                                               3 0.0  e  3 0.0  e  3 248.0                                                                              a-e                                                                               3 1.775                                                                              a-d                                                                               3 0.67                                                                               d-e                                                                               3 3.83                                                                               a-d                 30 + 2                                                                               3 0.0  e  3 0.0  e  3 234.4                                                                              a-e                                                                               3 1.777                                                                              a-d                                                                               3 2.42                                                                               b-e                                                                               3 3.42                                                                               a-d                 30 + 4                                                                               3 8.3  a-e                                                                               3 0.0  e  3 239.8                                                                              a-e                                                                               2 1.702                                                                              c-d                                                                               3 1.81                                                                               c-e                                                                               3 3.92                                                                               a-d                 30 + 6                                                                               3 16.7 a-c                                                                               3 8.3  a-c                                                                               3 228.6                                                                              b-e                                                                               1 1.894                                                                              a-d                                                                               3 1.39                                                                               d-e                                                                               3 4.00                                                                               a-d                 30 + 8                                                                               3 0.0  e  3 0.0  e  3 235.3                                                                              a-e                                                                               3 1.837                                                                              a-d                                                                               3 0.50                                                                               d-e                                                                               3 3.08                                                                               c-d                 40 + 2                                                                               3 0.0  e  3 0.0  e  3 244.4                                                                              a-e                                                                               3 1.750                                                                              a-d                                                                               3 1.83                                                                               c-e                                                                               3 3.67                                                                               a-d                 40 + 4                                                                               3 8.3  a-e                                                                               3 0.0  e  3 234.8                                                                              a-e                                                                               2 1.887                                                                              a-d                                                                               3 1.47                                                                               d-e                                                                               3 3.92                                                                               a-d                 40 + 6                                                                               3 0.0  e  3 0.0  e  3 253.6                                                                              a-c                                                                               3 1.723                                                                              a-d                                                                               3 0.33                                                                               d-e                                                                               3 3.67                                                                               a-d                 40 + 8                                                                               3 0.0  e  3 0.0  e  3 265.4                                                                              a-b                                                                               3 1.715                                                                              b-d                                                                               3 0.17                                                                               e  3 3.58                                                                               a-d                 __________________________________________________________________________

                                      EXPERIMENT NO. 21                            __________________________________________________________________________     Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of                                          broiler cockerels inoculated with E. maxima and E. tenella                                                                 Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 8.3  b-e                                                                               3 0.0  e  3 298.5                                                                              a  2 1.460                                                                              c  3 0.00                                                                               e  3 0.00                                                                               e                   IC                                                                             0     3 25.0 a-d                                                                               3 25.0 a-d                                                                               3 138.8                                                                              d-e                                                                               3          8.33                                                                               a-c                                                                               3 3.75                                                                               a-c                 NARASIN                                                                        10    3 0.0  e  3 0.0  e  3 148.0                                                                              d-e                                                                               3 2.458                                                                              b  3 8.75                                                                               a-c                                                                               3 3.75                                                                               a-c                 20    3 8.3  b-e                                                                               3 0.0  e  3 146.6                                                                              d-e                                                                               2 2.283                                                                              b-c                                                                               3 8.75                                                                               a-c                                                                               3 3.64                                                                               a-c                 30    3 16.7 b-e                                                                               3 16.7 a-e                                                                               3 158.2                                                                              c-e                                                                               1 2.618                                                                              b  3 8.08                                                                               a-c                                                                               3 3.67                                                                               a-c                 40    3 16.7 b-e                                                                               3 16.7 a-e                                                                               3 182.1                                                                              b-e                                                                               1 2.137                                                                              b-c                                                                               3 8.08                                                                               a-c                                                                               3 3.58                                                                               a-c                 Example                                                                        No. 56                                                                         2     3 8.3  b-e                                                                               3 0.0  e  3 122.9                                                                              e  2 3.397                                                                              a  3 8.17                                                                               a-c                                                                               3 3.92                                                                               a-c                 4     3 25.0 a-d                                                                               3 25.0 a-d                                                                               3 135.6                                                                              d-e                                                                               1 2.095                                                                              b-c                                                                               3 8.92                                                                               a-c                                                                               3 3.83                                                                               a-c                 6     3 8.3  b-e                                                                               3 8.3  a-e                                                                               3 135.1                                                                              d-e                                                                               2 2.570                                                                              b  3 9.00                                                                               a  3 3.75                                                                               a-c                 8     3 0.0  e  3 0.0  e  3 200.8                                                                              b-e                                                                               3 2.071                                                                              b-c                                                                               3 8.92                                                                               a-c                                                                               3 3.58                                                                               a-c                 NARA-                                                                          SIN +                                                                          Example                                                                        No. 56                                                                         10 + 2                                                                               3 25.0 a-d                                                                               3 25.0 a-d                                                                               3 179.2                                                                              b-e                                                                               1 2.052                                                                              b-c                                                                               3 8.83                                                                               a-c                                                                               3 3.50                                                                               b-c                 10 + 4                                                                               3 8.3  b-e                                                                               3 8.3  a-e                                                                               3 169.8                                                                              b-e                                                                               2 2.222                                                                              b-c                                                                               3 8.50                                                                               a-c                                                                               3 3.92                                                                               a-c                 10 + 6                                                                               3 0.0  e  3 0.0  e  3 213.6                                                                              b-e                                                                               3 1.958                                                                              b-c                                                                               3 8.58                                                                               a-c                                                                               3 3.67                                                                               a-c                 10 + 8                                                                               3 0.0  e  3 0.0  e  3 218.6                                                                              b-d                                                                               3 1.872                                                                              b-c                                                                               3 8.83                                                                               a-c                                                                               3 3.50                                                                               b-c                 20 + 2                                                                               3 50.0 a  3 25.0 a-d                                                                               3 198.7                                                                              b-e         3 8.22                                                                               a-c                                                                               3 4.00                                                                               a-b                 20 + 4                                                                               3 8.3  b-e                                                                               3 8.3  a-e                                                                               3 180.3                                                                              b-e                                                                               2 1.996                                                                              b-c                                                                               3 7.67                                                                               a-c                                                                               3 3.83                                                                               a-c                 20 + 6                                                                               3 0.0  e  3 0.0  e  3 187.1                                                                              b-e                                                                               3 2.041                                                                              b-c                                                                               3 8.50                                                                               a-c                                                                               3 3.67                                                                               a-c                 20 + 8                                                                               3 0.0  e  3 0.0  e  3 216.7                                                                              b-d                                                                               3 1.857                                                                              b-c                                                                               3 6.75                                                                               b-c                                                                               3 3.00                                                                               c                   30 + 2                                                                               3 0.0  e  3 0.0  e  3 181.8                                                                              b-e                                                                               3 2.170                                                                              b-c                                                                               3 8.75                                                                               a-c                                                                               3 3.75                                                                               a-c                 30 + 4                                                                               3 8.3  b-e                                                                               3 8.3  a-e                                                                               3 219.5                                                                              b-d                                                                               2 1.803                                                                              b-c                                                                               3 8.33                                                                               a-c                                                                               3 4.00                                                                               a-b                 30 + 6                                                                               3 8.3  b-e                                                                               3 0.0  e  3 253.7                                                                              a-b                                                                               2 1.680                                                                              b-c                                                                               3 8.08                                                                               a-c                                                                               3 3.50                                                                               b-c                 30 + 8                                                                               3 8.3  b-e                                                                               3 0.0  e  3 230.3                                                                              b-d                                                                               2 1.817                                                                              b-c                                                                               3 6.14                                                                               c  3 3.58                                                                               a-c                 40 + 2                                                                               3 8.3  b-e                                                                               3 0.0  e  3 198.7                                                                              b-e                                                                               2 2.186                                                                              b-c                                                                               3 8.42                                                                               a-c                                                                               3 3.53                                                                               a-c                 40 + 4                                                                               3 0.0  e  3 0.0  e  3 208.8                                                                              b-e                                                                               3 1.832                                                                              b-c                                                                               3 8.17                                                                               a-c                                                                               3 3.75                                                                               a-c                 40 + 6                                                                               3 0.0  e  3 0.0  e  3 226.9                                                                              b-d                                                                               3 1.817                                                                              b-c                                                                               3 7.67                                                                               a-c                                                                               3 3.50                                                                               b-c                 40 + 8                                                                               3 0.0  e  3 0.0  e  3 242.8                                                                              a-c                                                                               3 1.743                                                                              b-c                                                                               3 3.17                                                                               d  3 1.83                                                                               d                   __________________________________________________________________________

                                      EXPERIMENT NO. 22                            __________________________________________________________________________     Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of                                          broiler cockerels inoculated with E. tenella and E. acervulina                                                             Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 0.0  e  3 0.0  e  3 286.4                                                                              a  3 1.487                                                                              d  3 0.00                                                                               e  3 0.00                                                                               f                   IC                                                                             0     3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 217.7                                                                              b-e                                                                               2 1.827                                                                              a-d                                                                               3 5.50                                                                               a-b                                                                               3 3.75                                                                               a                   NARASIN                                                                        10    3 16.7 a-d                                                                               3 16.7 a-d                                                                               3 178.0                                                                              e  2 2.100                                                                              a  3 6.17                                                                               a-b                                                                               3 3.75                                                                               a                   20    3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 188.7                                                                              d-e                                                                               2 1.725                                                                              a-d                                                                               3 4.17                                                                               a-d                                                                               3 3.42                                                                               a-c                 30    3 0.0  e  3 0.0  e  3 195.5                                                                              b-e                                                                               3 1.873                                                                              a-d                                                                               3 3.58                                                                               b-d                                                                               3 3.33                                                                               a-c                 40    3 8.3  a-e                                                                               3 0.0  e  3 232.2                                                                              a-e                                                                               2 1.757                                                                              a-d                                                                               3 2.69                                                                               c-e                                                                               3 3.81                                                                               a                   Example                                                                        No. 57                                                                         2     3 16.7 a-d                                                                               3 16.7 a-d                                                                               3 195.4                                                                              c-e                                                                               1 1.911                                                                              a-d                                                                               3 6.58                                                                               a  3 3.92                                                                               a                   4     3 8.3  a-e                                                                               3 0.0  e  3 196.6                                                                              b-e                                                                               2 2.019                                                                              a-b                                                                               3 4.78                                                                               a-c                                                                               3 3.92                                                                               a                   6     3 0.0  e  3 0.0  e  3 223.1                                                                              a-e                                                                               3 1.757                                                                              a-d                                                                               3 2.08                                                                               c-e                                                                               3 3.67                                                                               a                   8     3 0.0  e  3 0.0  e  3 224.3                                                                              a-e                                                                               3 1.731                                                                              a-d                                                                               3 1.58                                                                               d-e                                                                               3 3.83                                                                               a                   NARA-                                                                          SIN +                                                                          Example                                                                        No. 57                                                                         10 + 2                                                                               3 25.0 a  3 25.0 a  3 213.9                                                                              b-e         3 4.00                                                                               a-d                                                                               3 3.67                                                                               a                   10 + 4                                                                               3 0.0  e  3 0.0  e  3 214.5                                                                              b-e                                                                               3 1.785                                                                              a-d                                                                               3 2.25                                                                               c-e                                                                               3 3.75                                                                               a                   10 + 6                                                                               3 16.7 a-d                                                                               3 16.7 a-d                                                                               3 248.8                                                                              a-d                                                                               2 1.689                                                                              a-d                                                                               3 0.67                                                                               e  3 3.42                                                                               a-c                 10 + 8                                                                               3 0.0  e  3 0.0  e  3 241.1                                                                              a-e                                                                               3 1.771                                                                              a-d                                                                               3 0.00                                                                               e  3 2.92                                                                               a-c                 20 + 2                                                                               3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 203.4                                                                              b-e                                                                               2 1.919                                                                              a-c                                                                               3 3.92                                                                               a-d                                                                               3 3.58                                                                               a                   20 + 4                                                                               3 0.0  e  3 0.0  e  3 241.4                                                                              a-e                                                                               3 1.683                                                                              b-d                                                                               3 0.75                                                                               e  3 3.50                                                                               a-b                 20 + 6                                                                               3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 255.4                                                                              a-d                                                                               2 1.667                                                                              b-d                                                                               3 0.08                                                                               e  3 3.42                                                                               a-c                 20 + 8                                                                               3 0.0  e  3 0.0  e  3 240.1                                                                              a-e                                                                               3 1.642                                                                              b-d                                                                               3 0.00                                                                               e  3 3.00                                                                               a-c                 30 + 2                                                                               3 0.0  e  3 0.0  e  3 243.6                                                                              a-e                                                                               3 1.645                                                                              b-d                                                                               3 1.75                                                                               d-e                                                                               3 3.67                                                                               a                   30 + 4                                                                               3 0.0  e  3 0.0  e  3 253.0                                                                              a-d                                                                               3 1.593                                                                              c-d                                                                               3 0.08                                                                               e  3 2.75                                                                               a-c                 30 + 6                                                                               3 0.0  e  3 0.0  e  3 254.6                                                                              a-d                                                                               3 1.614                                                                              c-d                                                                               3 0.08                                                                               e  3 2.42                                                                               b-d                 30 + 8                                                                               3 0.0  e  3 0.0  e  3 246.3                                                                              a-d                                                                               3 1.616                                                                              c-d                                                                               3 0.00                                                                               e  3 1.67                                                                               d-e                 40 + 2                                                                               3 0.0  e  3 0.0  e  3 239.8                                                                              a-e                                                                               3 1.645                                                                              b-d                                                                               3 1.58                                                                               d-e                                                                               3 3.67                                                                               a                   40 + 4                                                                               3 0.0  e  3 0.0  e  3 263.3                                                                              a-b                                                                               3 1.591                                                                              c-d                                                                               3 0.00                                                                               e  3 3.42                                                                               a-c                 40 + 6                                                                               3 0.0  e  3 0.0  e  3 256.5                                                                              a-d                                                                               3 1.589                                                                              c-d                                                                               3 0.00                                                                               e  3 2.33                                                                               c-d                 40 + 8                                                                               3 8.3  a-e                                                                               3 0.0  e  3 259.4                                                                              a-c                                                                               2 1.684                                                                              b-d                                                                               3 0.08                                                                               e  3 1.50                                                                               e                   __________________________________________________________________________

                                      EXPERIMENT NO. 23                            __________________________________________________________________________     Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of                                          broiler cockerels inoculated with E. maxima and E. tenella                                                                 Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 0.0  e  3 0.0  e  3 362.3                                                                              a  3 1.289                                                                              f  3 0.33                                                                               e  3 0.00                                                                               g                   IC                                                                             0     3 16.7 a-b                                                                               3 16.7 a-b                                                                               3 172.8                                                                              f  2 1.976                                                                              a  3 8.42                                                                               a  3 3.67                                                                               a-b                 NARASIN                                                                        10    3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 193.8                                                                              e-f                                                                               2 1.779                                                                              a-d                                                                               3 8.42                                                                               a  3 3.83                                                                               a-b                 20    3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 234.5                                                                              b-f                                                                               2 1.682                                                                              a-f                                                                               3 8.92                                                                               a  3 3.58                                                                               a-b                 30    3 8.3  a-e                                                                               3 0.0  e  3 253.0                                                                              b-e                                                                               2 1.639                                                                              a-f                                                                               3 8.75                                                                               a  3 3.64                                                                               a-b                 40    3 0.0  e  3 0.0  e  3 211.0                                                                              d-f                                                                               3 1.655                                                                              a-f                                                                               3 8.92                                                                               a  3 3.75                                                                               a-b                 Example                                                                        No.57                                                                          2     3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 178.3                                                                              e-f                                                                               2 1.933                                                                              a-b                                                                               3 8.58                                                                               a  3 3.58                                                                               a-b                 4     3 0.0  e  3 0.0  e  3 212.0                                                                              d-f                                                                               3 1.793                                                                              a-c                                                                               3 8.83                                                                               a  3 3.67                                                                               a-b                 6     3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 225.3                                                                              c-f                                                                               2 1.706                                                                              a-e                                                                               3 8.25                                                                               a  3 3.42                                                                               a-b                 8     3 0.0  e  3 0.0  e  3 246.6                                                                              b-f                                                                               3 1.635                                                                              a-f                                                                               3 7.58                                                                               a-b                                                                               3 3.58                                                                               a-b                 NARA-                                                                          SIN +                                                                          Example                                                                        No. 57                                                                         10 + 2                                                                               3 16.7 a-b                                                                               3 16.7 a-b                                                                               3 250.7                                                                              b-e                                                                               2 1.659                                                                              a-f                                                                               3 7.58                                                                               a-b                                                                               3 3.67                                                                               a-b                 10 + 4                                                                               3 0.0  e  3 0.0  e  3 241.4                                                                              b-f                                                                               3 1.544                                                                              c-f                                                                               3 7.75                                                                               a-b                                                                               3 3.50                                                                               a-b                 10 + 6                                                                               3 0.0  e  3 0.0  e  3 280.3                                                                              b-d                                                                               3 1.447                                                                              d-f                                                                               3 7.75                                                                               a-b                                                                               3 3.58                                                                               a-b                 10 + 8                                                                               3 0.0  e  3 0.0  e  3 301.3                                                                              a-c                                                                               3 1.428                                                                              d-f                                                                               3 1.67                                                                               d-e                                                                               3 1.67                                                                               d-f                 20 + 2                                                                               3 0.0  e  3 0.0  e  3 247.7                                                                              b-f                                                                               3 1.613                                                                              b-f                                                                               3 8.67                                                                               a  3 3.75                                                                               a-b                 20 + 4                                                                               3 0.0  e  3 0.0  e  3 291.6                                                                              a-d                                                                               3 1.453                                                                              d-f                                                                               3 6.50                                                                               a-c                                                                               3 2.92                                                                               a-c                 20 + 6                                                                               3 0.0  e  3 0.0  e  3 309.9                                                                              a-c                                                                               3 1.401                                                                              d-f                                                                               3 3.25                                                                               b-e                                                                               3 2.25                                                                               c-e                 20 + 8                                                                               3 0.0  e  3 0.0  e  3 303.3                                                                              a-c                                                                               3 1.429                                                                              d-f                                                                               3 1.42                                                                               d-e                                                                               3 1.42                                                                               e-f                 30 + 2                                                                               3 0.0  e  3 0.0  e  3 272.3                                                                              b-d                                                                               3 1.430                                                                              d-f                                                                               3 7.42                                                                               a-b                                                                               3 3.92                                                                               a                   30 + 4                                                                               3 8.3  a-e                                                                               3 8.3  a-e                                                                               3 294.7                                                                              a-c                                                                               2 1.495                                                                              c-f                                                                               3 3.42                                                                               b-e                                                                               3 2.58                                                                               b-d                 30 + 6                                                                               3 0.0  e  3 0.0  e  3 314.3                                                                              a-b                                                                               3 1.372                                                                              e-f                                                                               3 3.00                                                                               c-e                                                                               3 2.08                                                                               c-e                 30 + 8                                                                               3 0.0  e  3 0.0  e  3 296.4                                                                              a-c                                                                               3 1.429                                                                              d-f                                                                               3 1.17                                                                               d-e                                                                               3 0.75                                                                               f-g                 40 + 2                                                                               3 0.0  e  3 0.0  e  3 274.0                                                                              b-d                                                                               3 1.378                                                                              e-f                                                                               3 5.50                                                                               a-d                                                                               3 3.92                                                                               a                   40 + 4                                                                               3 0.0  e  3 0.0  e  3 286.6                                                                              a-d                                                                               3 1.451                                                                              d-f                                                                               3 2.00                                                                               d-e                                                                               3 2.17                                                                               c-e                 40 + 6                                                                               3 0.0  e  3 0.0  e  3 308.1                                                                              a-c                                                                               3 1.383                                                                              d-f                                                                               3 0.83                                                                               d-e                                                                               3 1.58                                                                               d-f                 40 + 8                                                                               3 0.0  e  3 0.0  e  3 292.9                                                                              a-d                                                                               3 1.428                                                                              d-f                                                                               3 0.83                                                                               d-e                                                                               3 0.67                                                                               f-g                 __________________________________________________________________________

                                      EXPERIMENT NO. 24                            __________________________________________________________________________     Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of                                          broiler cockerels inoculated with E. acervulina and E. tenella                                                             Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 8.3  a  3 0.0  a  3 308.4                                                                              a  2 1.433                                                                              b  3 0.00                                                                               e  3 0.00                                                                               e                   IC                                                                             0     3 16.7 a  3 16.7 a  3 209.7                                                                              b-c                                                                               1 1.796                                                                              a-b                                                                               3 6.75                                                                               a  3 3.75                                                                               a-b                 NARASIN                                                                        60    3 16.7 a  3 16.7 a  3 258.7                                                                              a-c                                                                               2 1.693                                                                              a-b                                                                               3 2.75                                                                               b-e                                                                               3 4.00                                                                               a                   80    3 0.0  a  3 0.0  a  3 230.9                                                                              a-c                                                                               3 1.741                                                                              a-b                                                                               3 0.83                                                                               c-e                                                                               3 3.75                                                                               a-b                 Example                                                                        No. 57                                                                         2     3 8.3  a  3 8.3  a  3 228.6                                                                              a-c                                                                               2 1.749                                                                              a-b                                                                               3 4.75                                                                               a-b                                                                               3 3.58                                                                               a-b                 4     3 0.0  a  3 0.0  a  3 245.9                                                                              a-c                                                                               3 1.799                                                                              a-b                                                                               3 3.17                                                                               b-d                                                                               3 3.92                                                                               a                   8     3 0.0  a  3 0.0  a  3 250.3                                                                              a-c                                                                               3 1.747                                                                              a-b                                                                               3 0.92                                                                               c-e                                                                               3 3.25                                                                               a-b                 Example                                                                        No. 56                                                                         2     3 8.3  a  3 8.3  a  3 192.5                                                                              c  2 1.914                                                                              a  3 6.00                                                                               a  3 3.75                                                                               a-b                 4     3 16.7 a  3 8.3  a  3 236.2                                                                              a-c                                                                               1 1.764                                                                              a-b                                                                               3 6.92                                                                               a  3 3.75                                                                               a-b                 8     3 8.3  a  3 8.3  a  3 238.7                                                                              a-c                                                                               2 1.776                                                                              a-b                                                                               3 3.33                                                                               b-c                                                                               3 3.17                                                                               a-b                 NARA-                                                                          SIN +                                                                          Example                                                                        No. 57                                                                         60 + 2                                                                               3 0.0  a  3 0.0  a  3 252.0                                                                              a-c                                                                               3 1.740                                                                              a-b                                                                               3 1.33                                                                               c-e                                                                               3 3.92                                                                               a                   60 + 4                                                                               3 0.0  a  3 0.0  a  3 270.9                                                                              a-c                                                                               3 1.612                                                                              a-b                                                                               3 0.42                                                                               d-e                                                                               3 3.92                                                                               a                   60 + 8                                                                               3 0.0  a  3 0.0  a  3 266.3                                                                              a-c                                                                               3 1.640                                                                              a-b                                                                               3 0.00                                                                               e  3 1.17                                                                               d                   80 + 2                                                                               3 16.7 a  3 16.7 a  3 255.1                                                                              a-c                                                                               1 1.676                                                                              a-b                                                                               3 2.33                                                                               c-e                                                                               3 3.92                                                                               a                   80 + 4                                                                               3 0.0  a  3 0.0  a  3 253.3                                                                              a-c                                                                               3 1.648                                                                              a-b                                                                               3 0.25                                                                               e  3 3.83                                                                               a                   80 + 8                                                                               3 0.0  a  3 0.0  a  3 274.5                                                                              a-c                                                                               3 1.645                                                                              a-b                                                                               3 0.00                                                                               e  3 1.92                                                                               c                   NARA-                                                                          SIN +                                                                          Example                                                                        No. 56                                                                         60 + 2                                                                               3 0.0  a  3 0.0  a  3 279.5                                                                              a-b                                                                               3 1.571                                                                              a-b                                                                               3 0.92                                                                               c-e                                                                               3 3.75                                                                               a-b                 60 + 4                                                                               3 0.0  a  3 0.0  a  3 258.8                                                                              a-c                                                                               3 1.659                                                                              a-b                                                                               3 1.08                                                                               c-e                                                                               3 3.92                                                                               a                   60 + 8                                                                               3 0.0  a  3 0.0  a  3 270.8                                                                              a-c                                                                               3 1.603                                                                              a-b                                                                               3 0.08                                                                               e  3 2.67                                                                               b-c                 80 + 2                                                                               3 8.3  a  3 8.3  a  3 240.0                                                                              a-c                                                                               2 1.769                                                                              a-b                                                                               3 2.08                                                                               c-e                                                                               3 4.00                                                                               a                   80 + 4                                                                               3 0.0  a  3 0.0  a  3 282.7                                                                              a-b                                                                               3 1.620                                                                              a-b                                                                               3 0.25                                                                               e  3 3.83                                                                               a                   80 + 8                                                                               3 0.0  a  3 0.0  a  3 272.1                                                                              a-c                                                                               3 1.610                                                                              a-b                                                                               3 0.00                                                                               e  3 2.17                                                                               c                   __________________________________________________________________________

                                      EXPERIMENT NO. 25                            __________________________________________________________________________     Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of                                          broiler cockerels inoculated with E. maxima and E. tenella                                                                 Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 8.3  a  3 0.0  a  3 265.5                                                                              a  2 1.432                                                                              d  3 0.00                                                                               d  3 0.00                                                                               d                   IC                                                                             0     3 8.3  a  3 8.3  a  3 160.9                                                                              d  2 1.880                                                                              b-c                                                                               3 8.67                                                                               a-b                                                                               3 3.83                                                                               a-b                 NARASIN                                                                        60    3 8.3  a  3 8.3  a  3 175.4                                                                              c-d                                                                               2 2.158                                                                              a-b                                                                               3 7.83                                                                               a-b                                                                               3 3.75                                                                               a-b                 80    3 25.0 a  3 25.0 a  3 212.1                                                                              a-d                                                                               1 1.774                                                                              b-d                                                                               3 5.83                                                                               a-c                                                                               3 3.58                                                                               a-b                 Example                                                                        No. 57                                                                         2     3 16.7 a  3 16.7 a  3 148.3                                                                              d  1 2.528                                                                              a  3 8.25                                                                               a-b                                                                               3 3.83                                                                               a-b                 4     3 25.0 a  3 16.7 a  3 159.8                                                                              d           3 8.17                                                                               a-b                                                                               3 3.31                                                                               a-b                 8     3 0.0  a  3 0.0  a  3 201.9                                                                              a-d                                                                               3 1.795                                                                              b-d                                                                               3 4.50                                                                               a-d                                                                               3 2.33                                                                               c                   Example                                                                        No. 56                                                                         2     3 16.7 a  3 16.7 a  3 146.8                                                                              d  1 2.283                                                                              a-b                                                                               3 8.17                                                                               a-b                                                                               3 3.67                                                                               a-b                 4     3 8.3  a  3 8.3  a  3 156.9                                                                              d  2 2.205                                                                              a-b                                                                               3 8.42                                                                               a-b                                                                               3 3.92                                                                               a                   8     3 8.3  a  3 8.3  a  3 158.3                                                                              d  2 2.027                                                                              b-c                                                                               3 8.92                                                                               a  3 3.67                                                                               a-b                 NARA-                                                                          SIN +                                                                          Example                                                                        No. 57                                                                         60 + 2                                                                               3 0.0  a  3 0.0  a  3 191.1                                                                              b-d                                                                               3 1.839                                                                              b-c                                                                               3 4.08                                                                               a-d                                                                               3 3.67                                                                               a-b                 60 + 4                                                                               3 8.3  a  3 8.3  a  3 248.0                                                                              a-b                                                                               2 1.618                                                                              c-d                                                                               3 3.58                                                                               b-d                                                                               3 3.83                                                                               a-b                 60 + 8                                                                               3 0.0  a  3 0.0  a  3 241.7                                                                              a-c                                                                               3 1.619                                                                              c-d                                                                               3 2.33                                                                               c-d                                                                               3 2.25                                                                               c                   80 + 2                                                                               3 16.7 a  3 16.7 a  3 200.8                                                                              a-d                                                                               2 1.890                                                                              b-c                                                                               3 6.00                                                                               a-c                                                                               3 3.83                                                                               a-b                 80 + 4                                                                               3 8.3  a  3 8.3  a  3 231.2                                                                              a-c                                                                               2 1.784                                                                              b-d                                                                               3 4.00                                                                               a-d                                                                               3 3.58                                                                               a-b                 80 + 8                                                                               3 0.0  a  3 0.0  a  3 238.6                                                                              a-c                                                                               3 1.624                                                                              c-d                                                                               3 0.67                                                                               d  3 2.25                                                                               c                   NARA-                                                                          SIN +                                                                          Example                                                                        No. 56                                                                         60 + 2                                                                               3 16.7 a  3 8.3  a  3 179.6                                                                              c-d                                                                               2 1.799                                                                              b-d                                                                               3 6.44                                                                               a-c                                                                               3 3.75                                                                               a-b                 60 + 4                                                                               3 8.3  a  3 8.3  a  3 213.1                                                                              a-d                                                                               2 1.809                                                                              b-d                                                                               3 6.42                                                                               a-c                                                                               3 3.83                                                                               a-b                 60 + 8                                                                               3 0.0  a  3 0.0  a  3 239.2                                                                              a-c                                                                               3 1.649                                                                              c-d                                                                               3 3.58                                                                               b-d                                                                               3 2.83                                                                               b-c                 80 + 2                                                                               3 8.3  a  3 8.3  a  3 191.4                                                                              b-d                                                                               2 1.766                                                                              b-d                                                                               3 7.08                                                                               a-c                                                                               3 4.00                                                                               a                   80 + 4                                                                               3 8.3  a  3 0.0  a  3 246.6                                                                              a-b                                                                               2 1.729                                                                              c-d                                                                               3 5.22                                                                               a-c                                                                               3 3.72                                                                               a-b                 80 + 8                                                                               3 16.7 a  3 8.3  a  3 229.3                                                                              a-c                                                                               1 1.555                                                                              c-d                                                                               3 0.17                                                                               d  3 2.47                                                                               c                   __________________________________________________________________________

                                      EXPERIMENT NO. 26                            __________________________________________________________________________     Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of                                          broiler cockerels inoculated with E. tenella and E. acervulina                                                             Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 0.0  h  3 0.0  h  3 313.9                                                                              a  3 1.511                                                                              h  3 0.00                                                                               e  3 0.00                                                                               h                   IC                                                                             0     3 16.3 a-d                                                                               3 16.7 a-c                                                                               3 242.4                                                                              e-h                                                                               2 1.800                                                                              a-b                                                                               3 3.83                                                                               a  3 3.50                                                                               a-e                 A80190                                                                         4     3 8.3  a-h                                                                               3 8.3  a-h                                                                               3 264.0                                                                              a-h                                                                               2 1.711                                                                              a-e                                                                               3 3.58                                                                               a  3 3.67                                                                               a-e                 8     3 16.7 a-d                                                                               3 16.7 a-c                                                                               3 261.1                                                                              a-h                                                                               1 1.511                                                                              h  3 3.67                                                                               a  3 3.33                                                                               a-e                 16    3 0.0  h  3 0.0  h  3 267.8                                                                              a-h                                                                               3 1.621                                                                              a-h                                                                               3 1.83                                                                               a-e                                                                               3 3.67                                                                               a-e                 Example                                                                        No. 57                                                                         2     3 0.0  h  3 0.0  h  3 253.4                                                                              b-h                                                                               3 1.647                                                                              a-h                                                                               3 3.08                                                                               a-b                                                                               3 3.67                                                                               a-e                 4     3 0.0  h  3 0.0  h  3 251.5                                                                              c-h                                                                               3 1.668                                                                              a-g                                                                               3 3.17                                                                               a-b                                                                               3 3.42                                                                               a-e                 8     3 0.0  h  3 0.0  h  3 249.8                                                                              d-h                                                                               3 1.665                                                                              a-h                                                                               3 1.42                                                                               a-e                                                                               3 3.50                                                                               a-e                 Example                                                                        No. 56                                                                         2     3 8.3  a-h                                                                               3 8.3  a-h                                                                               3 238.8                                                                              f-h                                                                               2 1.794                                                                              a-c                                                                               3 3.75                                                                               a  3 3.25                                                                               a-e                 4     3 8.3  a-h                                                                               3 0.0  h  3 273.1                                                                              a-h                                                                               2 1.628                                                                              a-h                                                                               3 3.00                                                                               a-e                                                                               3 3.61                                                                               a-e                 8     3 8.3  a-h                                                                               3 8.3  a-h                                                                               3 267.1                                                                              a-h                                                                               2 1.651                                                                              a-h                                                                               3 2.25                                                                               a-e                                                                               3 3.08                                                                               a-e                 A80190 +                                                                       Example                                                                        No. 57                                                                         4 + 2 3 0.0  h  3 0.0  h  3 220.5                                                                              h  3 1.810                                                                              a  3 2.67                                                                               a-d                                                                               3 3.67                                                                               a-e                 4 + 4 3 16.7 a-d                                                                               3 16.7 a-c                                                                               3 272.6                                                                              a-h                                                                               1 1.538                                                                              e-h                                                                               3 3.17                                                                               a-b                                                                               3 3.67                                                                               a-e                 4 + 8 3 0.0  h  3 0.0  h  3 277.3                                                                              a-h                                                                               3 1.622                                                                              a-h                                                                               3 0.00                                                                               e  3 2.00                                                                               e-g                 8 + 2 3 0.0  h  3 0.0  h  3 297.3                                                                              a-c                                                                               3 1.531                                                                              f-h                                                                               3 2.00                                                                               a-e                                                                               3 3.75                                                                               a-c                 8 + 4 3 8.3  a-h                                                                               3 8.3  a-h                                                                               3 283.5                                                                              a-g                                                                               2 1.545                                                                              c-h                                                                               3 1.67                                                                               a-e                                                                               3 3.00                                                                               b-e                 8 + 8 3 0.0  h  3 0.0  h  3 281.9                                                                              a-h                                                                               3 1.595                                                                              a-h                                                                               3 0.25                                                                               d-e                                                                               3 2.00                                                                               e-g                 16 + 2                                                                               3 0.0  h  3 0.0  h  3 271.5                                                                              a-h                                                                               3 1.620                                                                              a-h                                                                               3 0.83                                                                               b-e                                                                               3 3.42                                                                               a-e                 16 + 4                                                                               3 0.0  h  3 0.0  h  3 295.2                                                                              a-d                                                                               3 1.537                                                                              e-h                                                                               3 1.50                                                                               a-e                                                                               3 3.42                                                                               a-e                 16 + 8                                                                               3 8.3  a-h                                                                               3 0.0  h  3 287.7                                                                              a-f                                                                               2 1.598                                                                              a-h                                                                               3 0.00                                                                               e  3 0.81                                                                               g-h                 A80190 +                                                                       Example                                                                        No. 56                                                                         4 + 2 3 8.3  a-h                                                                               3 8.3  a-h                                                                               3 265.6                                                                              a-h                                                                               2 1.659                                                                              a-h                                                                               3 3.33                                                                               a-b                                                                               3 3.50                                                                               a-e                 4 + 4 3 0.0  h  3 0.0  h  3 257.3                                                                              a-h                                                                               3 1.697                                                                              a-f                                                                               3 2.50                                                                               a-e                                                                               3 3.92                                                                               a                   4 + 8 3 8.3  a-h                                                                               3 8.3  a-h                                                                               3 265.8                                                                              a-h                                                                               2 1.591                                                                              a-h                                                                               3 1.83                                                                               a-e                                                                               3 3.75                                                                               a-c                 8 + 2 3 0.0  h  3 0.0  h  3 231.4                                                                              g-h                                                                               3 1.766                                                                              a-d                                                                               3 2.08                                                                               a-e                                                                               3 3.33                                                                               a-e                 8 + 4 3 0.0  h  3 0.0  h  3 259.6                                                                              a-h                                                                               3 1.624                                                                              a-h                                                                               3 1.33                                                                               a-e                                                                               3 3.50                                                                               e-e                 8 + 8 3 0.0  h  3 0.0  h  3 268.2                                                                              a-h                                                                               3 1.644                                                                              a-h                                                                               3 1.50                                                                               a-e                                                                               3 2.67                                                                               c-f                 16 + 2                                                                               3 16.7 a-d                                                                               3 8.3  a-h                                                                               3 291.8                                                                              a-e                                                                               1 1.622                                                                              a-h                                                                               3 1.25                                                                               a-e                                                                               3 3.33                                                                               a-e                 16 + 4                                                                               3 0.0  h  3 0.0  h  3 281.7                                                                              a-h                                                                               3 1.585                                                                              a-h                                                                               3 0.92                                                                               b-e                                                                               3 3.08                                                                               a-e                 16 + 8                                                                               3 0.0  h  3 0.0  h  3 299.0                                                                              a-b                                                                               3 1.556                                                                              b-h                                                                               3 0.42                                                                               c-e                                                                               3 1.58                                                                               f-g                 __________________________________________________________________________

                                      EXPERIMENT NO. 27                            __________________________________________________________________________     Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of                                          broiler cockerels inoculated with E. maxima and E. tenella                                                                 Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 0.0  h  3 0.0  h  3 271.4                                                                              a  3 1.522                                                                              h  3 0.00                                                                               f  3 0.00                                                                               g                   IC                                                                             0     3 8.3  a-h                                                                               3 8.3  a-h                                                                               3 151.7                                                                              h  2 2.374                                                                              a  3 7.67                                                                               a-d                                                                               3 3.42                                                                               a-d                 A80190                                                                         4     3 0.0  h  3 0.0  h  3 199.9                                                                              a-h                                                                               3 1.903                                                                              b-e                                                                               3 8.17                                                                               a-d                                                                               3 3.58                                                                               a-d                 8     3 8.3  a-h                                                                               3 8.3  a-h                                                                               3 190.1                                                                              b-h                                                                               2 1.791                                                                              b-h                                                                               3 8.50                                                                               a-d                                                                               3 3.75                                                                               a-d                 16    3 0.0  h  3 0.0  h  3 190.8                                                                              a-h                                                                               3 1.882                                                                              b-f                                                                               3 8.00                                                                               a-d                                                                               3 3.75                                                                               a-d                 Example                                                                        No. 57                                                                         2     3 16.7 a-e                                                                               3 8.3  a-h                                                                               3 171.1                                                                              f-h                                                                               1 1.610                                                                              c-h                                                                               3 9.22                                                                               a  3 4.00                                                                               a                   4     3 8.3  a-h                                                                               3 0.0  h  3 218.6                                                                              a-h                                                                               2 1.688                                                                              b-h                                                                               3 8.50                                                                               a-d                                                                               3 3.75                                                                               a-d                 8     3 0.0  h  3 0.0  h  3 223.8                                                                              a-h                                                                               3 1.689                                                                              b-h                                                                               3 6.42                                                                               a-d                                                                               3 2.92                                                                               a-d                 Example                                                                        No. 56                                                                         2     3 8.3  a-h                                                                               3 8.3  a-h                                                                               3 164.4                                                                              g-h                                                                               2 2.079                                                                              a-b                                                                               3 8.00                                                                               a-d                                                                               3 3.67                                                                               a-d                 4     3 0.0  h  3 0.0  h  3 182.6                                                                              e-h                                                                               3 1.949                                                                              b-c                                                                               3 8.33                                                                               a-d                                                                               3 3.75                                                                               a-d                 8     3 0.0  h  3 0.0  h  3 224.0                                                                              a-h                                                                               3 1.670                                                                              b-h                                                                               3 6.25                                                                               a-d                                                                               3 3.33                                                                               a-d                 A80190 +                                                                       Example                                                                        No. 57                                                                         4 + 2 3 8.3  a-h                                                                               3 8.3  a-h                                                                               3 188.4                                                                              d-h                                                                               2 1.924                                                                              b-d                                                                               3 7.92                                                                               a-d                                                                               3 3.58                                                                               a-d                 4 + 4 3 16.7 a-e                                                                               3 8.3  a-h                                                                               3 204.8                                                                              a-h                                                                               2 1.793                                                                              b-h                                                                               3 6.08                                                                               b-d                                                                               3 3.67                                                                               a-d                 4 + 8 3 8.3  a-h                                                                               3 0.0  h  3 229.2                                                                              a-h                                                                               2 1.623                                                                              b-h                                                                               3 3.92                                                                               d-e                                                                               3 2.78                                                                               c-d                 8 + 2 3 0.0  h  3 0.0  h  3 199.9                                                                              a-h                                                                               3 1.817                                                                              b-h                                                                               3 8.83                                                                               a-b                                                                               3 3.58                                                                               a-d                 8 + 4 3 16.7 a-e                                                                               3 16.7 a-b                                                                               3 239.5                                                                              a-f                                                                               1 1.567                                                                              e-h                                                                               3 6.42                                                                               a-d                                                                               3 3.33                                                                               a-d                 8 + 8 3 0.0  h  3 0.0  h  3 260.8                                                                              a-b                                                                               3 1.549                                                                              g-h                                                                               3 1.33                                                                               e-f                                                                               3 1.83                                                                               e-f                 16 + 2                                                                               3 8.3  a-h                                                                               3 8.3  a-h                                                                               3 228.4                                                                              a-h                                                                               2 1.739                                                                              b-h                                                                               3 6.83                                                                               a-d                                                                               3 3.42                                                                               a-d                 16 + 4                                                                               3 0.0  h  3 0.0  h  3 238.3                                                                              a-g                                                                               3 1.660                                                                              b-h                                                                               3 7.08                                                                               a-d                                                                               3 3.42                                                                               a-d                 16 + 8                                                                               3 0.0  h  3 0.0  h  3 237.5                                                                              a-g                                                                               3 1.562                                                                              f-h                                                                               3 0.83                                                                               e-f                                                                               3 1.25                                                                               f                   A80190 +                                                                       Example                                                                        No. 56                                                                         4 + 2 3 8.3  a-h                                                                               3 8.3  a-h                                                                               3 190.1                                                                              c-h                                                                               2 1.841                                                                              b-g                                                                               3 6.92                                                                               a-d                                                                               3 2.83                                                                               b-d                 4 + 4 3 0.0  h  3 0.0  h  3 230.1                                                                              a-h                                                                               3 1.638                                                                              b-h                                                                               3 8.17                                                                               a-d                                                                               3 3.08                                                                               a-d                 4 + 8 3 8.3  a-h                                                                               3 0.0  h  3 241.4                                                                              a-d                                                                               2 1.586                                                                              d-h                                                                               3 6.97                                                                               a-d                                                                               3 3.36                                                                               a-d                 8 + 2 3 8.3  a-h                                                                               3 8.3  a-h                                                                               3 199.2                                                                              a-h                                                                               2 1.828                                                                              b-h                                                                               3 7.42                                                                               a-d                                                                               3 3.75                                                                               a-d                 8 + 4 3 0.0  h  3 0.0  h  3 212.1                                                                              a-h                                                                               3 1.714                                                                              b-h                                                                               3 8.00                                                                               a-d                                                                               3 3.58                                                                               a-d                 8 + 8 3 0.0  h  3 0.0  h  3 240.1                                                                              a-e                                                                               3 1.615                                                                              b-h                                                                               3 4.00                                                                               c-e                                                                               3 2.50                                                                               d-e                 16 + 2                                                                               3 16.7 a-e                                                                               3 16.7 a-b                                                                               3 238.0                                                                              a-g                                                                               2 1.691                                                                              b-h                                                                               3 7.50                                                                               a-d                                                                               3 3.67                                                                               a-d                 16 + 4                                                                               3 0.0  h  3 0.0  h  3 236.4                                                                              a-g                                                                               3 1.640                                                                              b-h                                                                               3 7.17                                                                               a-d                                                                               3 3.50                                                                               a-d                 16 + 8                                                                               3 16.7 a-e                                                                               3 8.3  a-h                                                                               3 256.3                                                                              a-c                                                                               2 1.622                                                                              b-h                                                                               3 1.75                                                                               e-f                                                                               3 1.69                                                                               e-f                 __________________________________________________________________________

                                      EXPERIMENT NO. 28                            __________________________________________________________________________     Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of                                          broiler cockerels inoculated with E. tenella and E. acervulina                                                             Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 0.0  h  3 0.0  h  3 308.2                                                                              a  3 1.475                                                                              c-d                                                                               3 0.00                                                                               h  3 0.00                                                                               f                   IC                                                                             0     3 8.3  a-h                                                                               3 8.3  a-h                                                                               3 214.7                                                                              e-h                                                                               2 1.872                                                                              b  3 6.33                                                                               a-b                                                                               3 3.58                                                                               a-b                 A80190                                                                         4     3 33.3 a  3 25.0 a-d                                                                               3 193.0                                                                              g-h         3 7.00                                                                               a  3 3.44                                                                               a-b                 8     3 16.7 a-h                                                                               3 0.0  h  3 274.0                                                                              a-f                                                                               1 1.570                                                                              b-d                                                                               3 4.39                                                                               a-e                                                                               3 2.83                                                                               a-b                 16    3 25.0 a-e                                                                               3 16.7 a-g                                                                               3 212.0                                                                              f-h                                                                               2 1.590                                                                              b-d                                                                               3 3.61                                                                               a-h                                                                               3 2.89                                                                               a-b                 Example                                                                        No. 57                                                                         2     3 8.3  a-h                                                                               3 8.3  a-h                                                                               3 168.0                                                                              h  2 2.331                                                                              a  3 4.00                                                                               a-f                                                                               3 3.50                                                                               a-b                 4     3 16.7 a-h                                                                               3 16.7 a-g                                                                               3 222.2                                                                              c-h                                                                               2 1.922                                                                              b  3 5.08                                                                               a-c                                                                               3 3.58                                                                               a-b                 8     3 8.3  a-h                                                                               3 8.3  a-h                                                                               3 261.3                                                                              a-f                                                                               2 1.541                                                                              c-d                                                                               3 2.42                                                                               c-h                                                                               3 3.08                                                                               a-b                 Example                                                                        No. 56                                                                         2     3 8.3  a-h                                                                               3 8.3  a-h                                                                               3 242.9                                                                              a-g                                                                               2 1.888                                                                              b  3 4.75                                                                               a-d                                                                               3 3.67                                                                               a-b                 4     3 16.7 a-h                                                                               3 16.7 a-g                                                                               3 217.8                                                                              d-h                                                                               1 1.622                                                                              b-d                                                                               3 5.42                                                                               a-c                                                                               3 3.42                                                                               a-b                 8     3 16.7 a-h                                                                               3 8.3  a-h                                                                               3 226.8                                                                              b-g                                                                               2 1.726                                                                              b-d                                                                               3 3.75                                                                               a-g                                                                               3 3.19                                                                               a-b                 A80190 +                                                                       Example                                                                        No. 57                                                                         4 + 2 3 25.0 a-e                                                                               3 25.0 a-d                                                                               3 245.4                                                                              a-g                                                                               1 1.814                                                                              b-c                                                                               3 4.94                                                                               a-c                                                                               3 3.56                                                                               a-b                 4 + 4 3 8.3  a-h                                                                               3 8.3  a-h                                                                               3 262.9                                                                              a-f                                                                               2 1.684                                                                              b-d                                                                               3 3.25                                                                               b-h                                                                               3 3.33                                                                               a-b                 4 + 8 3 0.0  h  3 0.0  h  3 282.8                                                                              a-e                                                                               3 1.584                                                                              b-d                                                                               3 0.08                                                                               h  3 2.25                                                                               b-d                 8 + 2 3 25.0 a-e                                                                               3 25.0 a-d                                                                               3 243.0                                                                              a-g         3 3.92                                                                               a-f                                                                               3 3.42                                                                               a-b                 8 + 4 3 8.3  a-h                                                                               3 0.0  h  3 271.7                                                                              a-f                                                                               2 1.609                                                                              b-d                                                                               3 1.19                                                                               e-h                                                                               3 3.03                                                                               a-b                 8 + 8 3 8.3  a-h                                                                               3 0.0  h  3 275.1                                                                              a-f                                                                               2 1.570                                                                              b-d                                                                               3 0.00                                                                               h  3 1.36                                                                               c-e                 16 + 2                                                                               3 8.3  a-h                                                                               3 8.3  a-h                                                                               3 255.9                                                                              a-g                                                                               2 1.725                                                                              b-d                                                                               3 3.08                                                                               b-h                                                                               3 3.33                                                                               a-b                 16 + 4                                                                               3 0.0  h  3 0.0  h  3 289.6                                                                              a-b                                                                               3 1.543                                                                              c-d                                                                               3 0.00                                                                               h  3 1.25                                                                               d-e                 16 + 8                                                                               3 0.0  h  3 0.0  h  3 282.4                                                                              a-f                                                                               3 1.619                                                                              b-d                                                                               3 0.00                                                                               h  3 0.17                                                                               f                   A80190 +                                                                       Example                                                                        No. 56                                                                         4 + 2 3 25.0 a-e                                                                               3 25.0 a-d                                                                               3 249.5                                                                              a-g                                                                               1 1.468                                                                              d  3 5.17                                                                               a-c                                                                               3 3.42                                                                               a-b                 4 + 4 3 0.0  h  3 0.0  h  3 273.3                                                                              a-f                                                                               3 1.589                                                                              b-d                                                                               3 2.75                                                                               b-h                                                                               3 3.25                                                                               a-b                 4 + 8 3 8.3  a-h                                                                               3 0.0  h  3 237.5                                                                              a-g                                                                               2 1.663                                                                              b-d                                                                               3 1.00                                                                               e-h                                                                               3 2.94                                                                               a-b                 8 + 2 3 8.3  a-h                                                                               3 8.3  a-h                                                                               3 243.8                                                                              a-g                                                                               2 1.787                                                                              b-d                                                                               3 3.33                                                                               b-h                                                                               3 3.67                                                                               a-b                 8 + 4 3 8.3  a-h                                                                               3 8.3  a-h                                                                               3 246.1                                                                              a-g                                                                               2 1.661                                                                              b-d                                                                               3 3.25                                                                               b-h                                                                               3 3.33                                                                               a-b                 8 + 8 3 0.0  h  3 0.0  h  3 270.0                                                                              a-f                                                                               3 1.550                                                                              c-d                                                                               3 0.58                                                                               f-h                                                                               3 2.42                                                                               a-c                 16 + 2                                                                               3 0.0  h  3 0.0  h  3 272.7                                                                              a-f                                                                               3 1.580                                                                              b-d                                                                               3 1.33                                                                               d-h                                                                               3 2.42                                                                               a-c                 16 + 4                                                                               3 0.0  h  3 0.0  h  3 289.3                                                                              a-c                                                                               3 1.480                                                                              c-d                                                                               3 0.42                                                                               f-h                                                                               3 1.50                                                                               c-e                 16 + 8                                                                               3 0.0  h  3 0.0  h  3 283.8                                                                              a-d                                                                               3 1.494                                                                              c-d                                                                               3 0.25                                                                               g-h                                                                               3 0.83                                                                               e-f                 __________________________________________________________________________

                                      EXPERIMENT NO. 29                            __________________________________________________________________________     Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of                                          broiler cockerels inoculated with E. tenella and E. maxima                                                                 Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     3 0.0  h  3 0.0  h  3 320.3                                                                              a  3 1.523                                                                              d-e                                                                               3 0.00                                                                               g  3 0.00                                                                               g                   IC                                                                             0     3 16.7 a-h                                                                               3 16.7 a-h                                                                               3 182.6                                                                              h-j                                                                               2 1.973                                                                              a-b                                                                               3 9.08                                                                               a  3 3.75                                                                               a-e                 A80190                                                                         4     3 25.0 a-h                                                                               3 25.0 a-g                                                                               3 217.8                                                                              c-j                                                                               2 1.883                                                                              a-e                                                                               3 9.00                                                                               a  3 3.75                                                                               a-e                 8     3 25.0 a-h                                                                               3 25.0 a-g                                                                               3 213.1                                                                              c-j                                                                               2 1.955                                                                              a-c                                                                               3 7.50                                                                               a-d                                                                               3 3.83                                                                               a-e                 16    3 25.0 a-h                                                                               3 16.7 a-h                                                                               3 208.4                                                                              d-j                                                                               1 1.943                                                                              a-d                                                                               3 7.75                                                                               a-d                                                                               3 4.00                                                                               a                   Example                                                                        No. 57                                                                         2     3 25.0 a-h                                                                               3 25.0 a-g                                                                               3 161.4                                                                              j  1 2.083                                                                              a  3 8.58                                                                               a-b                                                                               3 3.83                                                                               a-e                 4     3 41.7 a-b                                                                               3 33.3 a-b                                                                               3 172.2                                                                              i-j         3 7.89                                                                               a-d                                                                               3 3.56                                                                               a-e                 8     3 8.3  b-h                                                                               3 8.3  a-h                                                                               3 237.4                                                                              b-j                                                                               2 1.793                                                                              a-e                                                                               3 7.17                                                                               a-d                                                                               3 3.67                                                                               a-e                 Example                                                                        No. 56                                                                         2     3 25.0 a-h                                                                               3 25.0 a-g                                                                               3 173.8                                                                              i-j                                                                               1 1.789                                                                              a-e                                                                               3 7.42                                                                               a-d                                                                               3 3.75                                                                               a-e                 4     3 50.0 a  3 50.0 a  3 192.9                                                                              f-j         3 7.25                                                                               a-d                                                                               3 3.83                                                                               a-e                 8     3 0.0  h  3 0.0  h  3 190.1                                                                              g-j                                                                               3 2.087                                                                              a  3 6.83                                                                               a-e                                                                               3 3.33                                                                               a-e                 A80190 +                                                                       Example                                                                        No. 57                                                                         4 + 2 3 25.0 a-h                                                                               3 25.0 a-g                                                                               3 216.5                                                                              c-j                                                                               1 1.701                                                                              a-e                                                                               3 8.25                                                                               a-c                                                                               3 3.92                                                                               a-b                 4 + 4 3 8.3  b-h                                                                               3 8.3  a-h                                                                               3 239.4                                                                              b-j                                                                               2 1.820                                                                              a-e                                                                               3 6.00                                                                               a-e                                                                               3 3.67                                                                               a-e                 4 + 8 3 0.0  h  3 0.0  h  3 270.4                                                                              a-f                                                                               3 1.616                                                                              b-e                                                                               3 0.17                                                                               g  3 3.17                                                                               a-e                 8 + 2 3 25.0 a-h                                                                               3 8.3  a-h                                                                               3 221.0                                                                              c-j                                                                               1 1.831                                                                              a-e                                                                               3 7.69                                                                               a-d                                                                               3 3.89                                                                               a-c                 8 + 4 3 16.7 a-h                                                                               3 8.3  a-h                                                                               3 250.7                                                                              a-i                                                                               1 1.709                                                                              a-e                                                                               3 4.56                                                                               b-f                                                                               3 3.72                                                                               a-e                 8 + 8 3 0.0  h  3 0.0  h  3 287.0                                                                              a-d                                                                               3 1.554                                                                              d-e                                                                               3 0.33                                                                               g  3 2.08                                                                               e-f                 16 + 2                                                                               3 16.7 a-h                                                                               3 16.7 a-h                                                                               3 275.2                                                                              a-e                                                                               1 1.628                                                                              a-e                                                                               3 4.25                                                                               c-f                                                                               3 2.75                                                                               b-e                 16 + 4                                                                               3 16.7 a-h                                                                               3 8.3  a-h                                                                               3 263.4                                                                              a-g                                                                               1 1.649                                                                              a-e                                                                               3 3.17                                                                               e-g                                                                               3 2.94                                                                               a-e                 16 + 8                                                                               3 8.3  b-h                                                                               3 0.0  h  3 291.4                                                                              a-c                                                                               2 1.557                                                                              c-e                                                                               3 0.00                                                                               g  3 0.44                                                                               g                   A80190 +                                                                       Example                                                                        No. 56                                                                         4 + 2 3 25.0 a-h                                                                               3 16.7 a-h                                                                               3 218.1                                                                              c-j                                                                               1 1.723                                                                              a-e                                                                               3 8.39                                                                               a-c                                                                               3 3.44                                                                               a-e                 4 + 4 3 16.7 a-h                                                                               3 16.7 a-h                                                                               3 232.5                                                                              b-j                                                                               1 1.873                                                                              a-e                                                                               3 7.75                                                                               a-d                                                                               3 3.75                                                                               a-e                 4 + 8 3 8.3  b-h                                                                               3 8.3  a-h                                                                               3 260.9                                                                              a-h                                                                               2 1.584                                                                              b-e                                                                               3 4.00                                                                               d-f                                                                               3 3.50                                                                               a-e                 8 + 2 3 8.3  b-h                                                                               3 8.3  a-h                                                                               3 206.1                                                                              e-j                                                                               2 1.873                                                                              a-e                                                                               3 8.08                                                                               a-d                                                                               3 3.58                                                                               a-e                 8 + 4 3 0.0  h  3 0.0  h  3 230.4                                                                              c-j                                                                               3 1.752                                                                              a-e                                                                               3 5.58                                                                               a-e                                                                               3 3.58                                                                               a-e                 8 + 8 3 0.0  h  3 0.0  h  3 292.6                                                                              a-c                                                                               3 1.517                                                                              e  3 1.42                                                                               f-g                                                                               3 2.08                                                                               e-f                 16 + 2                                                                               3 8.3  b-h                                                                               3 8.3  a-h                                                                               3 248.7                                                                              a-i                                                                               2 1.744                                                                              a-e                                                                               3 5.25                                                                               a-e                                                                               3 3.25                                                                               a-e                 16 + 4                                                                               3 8.3  b-h                                                                               3 0.0  h  3 267.5                                                                              a-g                                                                               2 1.542                                                                              d-e                                                                               3 3.22                                                                               e-g                                                                               3 2.47                                                                               c-f                 16 + 8                                                                               3 8.3  b-h                                                                               3 0.0  h  3 308.1                                                                              a-b                                                                               2 1.537                                                                              d-e                                                                               3 0.17                                                                               g  3 1.17                                                                               f-g                 __________________________________________________________________________

                                      EXPERIMENT NO. 30                            __________________________________________________________________________     Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of                                          broiler cockerels inoculated with E. tenella and E. acervulina                                                             Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     4 0.0  e  4 0.0  a  4 330.6                                                                              a  4 1.394                                                                              d  4 0.00                                                                               f  4 0.00                                                                               e                   IC                                                                             0     4 0.0  e  4 0.0  a  4 276.3                                                                              d-e                                                                               4 1.641                                                                              a-b                                                                               4 5.88                                                                               a  4 3.56                                                                               a-b                 A80190                                                                         10    4 0.0  e  4 0.0  a  4 293.4                                                                              a-e                                                                               4 1.515                                                                              a-d                                                                               4 5.19                                                                               a-b                                                                               4 3.00                                                                               a-c                 20    4 0.0  e  4 0.0  a  4 300.4                                                                              a-e                                                                               4 1.449                                                                              c-d                                                                               4 3.56                                                                               b-d                                                                               4 3.00                                                                               a-c                 30    4 12.5 a-c                                                                               4 0.0  a  4 313.9                                                                              a-c                                                                               3 1.450                                                                              c-d                                                                               4 2.06                                                                               d-f                                                                               4 3.00                                                                               a-c                 40    4 0.0  e  4 0.0  a  4 321.9                                                                              a-b                                                                               4 1.391                                                                              d  4 2.38                                                                               c-e                                                                               4 2.44                                                                               a-c                 Example                                                                        No. 57                                                                         2     4 0.0  e  4 0.0  a  4 270.8                                                                              e  4 1.662                                                                              a  4 5.81                                                                               a  4 3.69                                                                               a                   4     4 0.0  e  4 0.0  a  4 284.4                                                                              a-e                                                                               4 1.583                                                                              a-c                                                                               4 4.81                                                                               a-b                                                                               4 3.56                                                                               a-b                 6     4 0.0  e  4 0.0  a  4 277.8                                                                              b-e                                                                               4 1.568                                                                              a-d                                                                               4 4.75                                                                               a-b                                                                               4 2.38                                                                               a-c                 8     4 12.5 a-c                                                                               4 0.0  a  4 277.2                                                                              b-e                                                                               2 1.617                                                                              a-c                                                                               4 4.06                                                                               a-c                                                                               4 2.48                                                                               a-c                 A80190 +                                                                       Example                                                                        No. 57                                                                         10 + 2                                                                               4 0.0  e  4 0.0  a  4 283.6                                                                              a-e                                                                               4 1.543                                                                              a-d                                                                               4 4.06                                                                               a-c                                                                               4 3.13                                                                               a-c                 10 + 4                                                                               4 0.0  e  4 0.0  a  4 301.3                                                                              a-e                                                                               4 1.437                                                                              c-d                                                                               4 2.44                                                                               c-e                                                                               4 2.69                                                                               a-c                 10 + 6                                                                               4 6.3  a-e                                                                               4 0.0  a  4 276.5                                                                              b-e                                                                               3 1.559                                                                              a-d                                                                               4 2.04                                                                               d-f                                                                               4 2.29                                                                               b-c                 10 + 8                                                                               4 0.0  e  4 0.0  a  4 280.6                                                                              a-e                                                                               4 1.566                                                                              a-d                                                                               4 1.19                                                                               e-f                                                                               4 1.00                                                                               d-e                 20 + 2                                                                               4 0.0  e  4 0.0  a  4 306.9                                                                              a-e                                                                               4 1.430                                                                              c-d                                                                               4 1.63                                                                               e-f                                                                               4 2.56                                                                               a-c                 20 + 4                                                                               4 0.0  e  4 0.0  a  4 291.8                                                                              a-e                                                                               4 1.514                                                                              a-d                                                                               4 1.69                                                                               e-f                                                                               4 1.75                                                                               c-d                 20 + 6                                                                               4 0.0  e  4 0.0  a  4 289.5                                                                              a-e                                                                               4 1.508                                                                              a-d                                                                               4 0.88                                                                               e-f                                                                               4 1.00                                                                               d-e                 20 + 8                                                                               4 6.3  a-e                                                                               4 0.0  a  4 276.5                                                                              c-e                                                                               3 1.498                                                                              a-d                                                                               4 0.29                                                                               f  4 1.13                                                                               d-e                 30 + 2                                                                               4 12.5 a-c                                                                               4 0.0  a  4 296.3                                                                              a-e                                                                               2 1.487                                                                              a-d                                                                               4 1.71                                                                               e-f                                                                               4 2.52                                                                               a-c                 30 + 4                                                                               4 0.0  e  4 0.0  a  4 289.7                                                                              a-e                                                                               4 1.504                                                                              a-d                                                                               4 1.06                                                                               e-f                                                                               4 1.13                                                                               d-e                 30 + 6                                                                               4 0.0  e  4 0.0  a  4 303.2                                                                              a-e                                                                               4 1.520                                                                              a-d                                                                               4 0.25                                                                               f  4 0.56                                                                               d-e                 30 + 8                                                                               4 0.0  e  4 0.0  a  4 278.3                                                                              b-e                                                                               4 1.528                                                                              a-d                                                                               4 0.19                                                                               f  4 0.44                                                                               e                   40 + 2                                                                               4 0.0  e  4 0.0  a  4 303.3                                                                              a-e                                                                               4 1.448                                                                              c-d                                                                               4 0.81                                                                               e-f                                                                               4 1.75                                                                               c-d                 40 + 4                                                                               4 0.0  e  4 0.0  a  4 311.1                                                                              a-d                                                                               4 1.451                                                                              b-d                                                                               4 0.06                                                                               f  4 0.19                                                                               e                   40 + 6                                                                               4 0.0  e  4 0.0  a  4 286.8                                                                              a-e                                                                               4 1.571                                                                              a-d                                                                               4 0.19                                                                               f  4 0.25                                                                               e                   40 + 8                                                                               4 0.0  e  4 0.0  a  4 296.6                                                                              a-e                                                                               4 1.475                                                                              b-d                                                                               4 0.00                                                                               f  4 0.00                                                                               e                   __________________________________________________________________________

                                      EXPERIMENT NO. 31                            __________________________________________________________________________     Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of                                          broiler cockerels inoculated with E. tenella and E. acervulina                                                             Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     4 0.0  e  4 0.0  e  4 332.1                                                                              a  4 1.439                                                                              f  4 0.00                                                                               g  4 0.00                                                                               g                   IC                                                                             0     4 0.0  e  4 0.0  e  4 283.9                                                                              a-e                                                                               4 1.688                                                                              a-c                                                                               4 5.56                                                                               a  4 3.00                                                                               a-c                 A80190 +                                                                       Example                                                                        No. 57                                                                         2 + 2 4 6.3  a-e                                                                               4 0.0  e  4 285.4                                                                              a-e                                                                               3 1.621                                                                              a-f                                                                               4 5.31                                                                               a  4 3.21                                                                               a-b                 2 + 4 4 0.0  e  4 0.0  e  4 280.3                                                                              a-e                                                                               4 1.758                                                                              a  4 3.94                                                                               a-c                                                                               4 3.13                                                                               a-c                 2 + 8 4 0.0  e  4 0.0  e  4 280.8                                                                              a-e                                                                               4 1.637                                                                              a-e                                                                               4 2.31                                                                               c-g                                                                               4 2.00                                                                               b-d                 4 + 2 4 0.0  e  4 0.0  e  4 285.4                                                                              a-e                                                                               4 1.657                                                                              a-d                                                                               4 4.69                                                                               a-b                                                                               4 3.06                                                                               a-c                 4 + 4 4 0.0  e  4 0.0  e  4 301.2                                                                              a-e                                                                               4 1.545                                                                              c-f                                                                               4 3.50                                                                               a-d                                                                               4 3.50                                                                               a                   4 + 8 4 0.0  e  4 0.0  e  4 289.6                                                                              a-e                                                                               4 1.605                                                                              a-f                                                                               4 1.25                                                                               d-g                                                                               4 1.38                                                                               d-f                 8 + 2 4 0.0  e  4 0.0  e  4 284.8                                                                              a-e                                                                               4 1.604                                                                              a-f                                                                               4 4.06                                                                               a-c                                                                               4 3.38                                                                               a                   8 + 4 4 0.0  e  4 0.0  e  4 296.9                                                                              a-e                                                                               4 1.574                                                                              b-f                                                                               4 3.13                                                                               b-e                                                                               4 3.13                                                                               a-c                 8 + 8 4 0.0  e  4 0.0  e  4 274.3                                                                              d-e                                                                               4 1.572                                                                              b-f                                                                               4 0.81                                                                               e-g                                                                               4 0.75                                                                               e-g                 16 + 2                                                                               4 0.0  e  4 0.0  e  4 323.2                                                                              a-b                                                                               4 1.476                                                                              e-f                                                                               4 2.81                                                                               b-f                                                                               4 3.38                                                                               a                   16 + 4                                                                               4 0.0  e  4 0.0  e  4 298.3                                                                              a-e                                                                               4 1.635                                                                              a-e                                                                               4 2.13                                                                               c-g                                                                               4 3.13                                                                               a-c                 16 + 8                                                                               4 0.0  e  4 0.0  e  4 274.6                                                                              c-e                                                                               4 1.558                                                                              b-f                                                                               4 0.56                                                                               f-g                                                                               4 0.56                                                                               e-g                 A82810 +                                                                       Example                                                                        No. 57                                                                         2 + 2 4 0.0  e  4 0.0  e  4 296.0                                                                              a-e                                                                               4 1.567                                                                              b-f                                                                               4 3.50                                                                               a-d                                                                               4 3.13                                                                               a-c                 2 + 4 4 0.0  e  4 0.0  e  4 300.3                                                                              a-e                                                                               4 1.549                                                                              c-f                                                                               4 4.06                                                                               a-c                                                                               4 3.06                                                                               a-c                 2 + 8 4 6.3  a-e                                                                               4 0.0  e  4 290.6                                                                              a-e                                                                               3 1.614                                                                              a-f                                                                               4 0.06                                                                               g  4 0.38                                                                               e-g                 4 + 2 4 6.3  a-e                                                                               4 0.0  e  4 320.4                                                                              a-c                                                                               3 1.513                                                                              c-f                                                                               4 2.54                                                                               b-f                                                                               4 3.06                                                                               a-c                 4 + 4 4 0.0  e  4 0.0  e  4 305.3                                                                              a-e                                                                               4 1.538                                                                              c-f                                                                               4 1.88                                                                               c-g                                                                               4 1.88                                                                               c-d                 4 + 8 4 0.0  e  4 0.0  e  4 291.1                                                                              a-e                                                                               4 1.600                                                                              a-f                                                                               4 0.00                                                                               g  4 0.25                                                                               e-g                 8 + 2 4 0.0  e  4 0.0  e  4 312.3                                                                              a-d                                                                               4 1.506                                                                              d-f                                                                               4 2.94                                                                               b-e                                                                               4 1.50                                                                               d-e                 8 + 4 4 6.3  a-e                                                                               4 6.3  a  4 303.1                                                                              a-e                                                                               3 1.553                                                                              b-f                                                                               4 1.25                                                                               d-g                                                                               4 1.44                                                                               d-f                 8 + 8 4 0.0  e  4 0.0  e  4 282.1                                                                              a-e                                                                               4 1.579                                                                              b-f                                                                               4 0.19                                                                               g  4 0.19                                                                               f-g                 16 + 2                                                                               4 0.0  e  4 0.0  e  4 276.6                                                                              b-e                                                                               4 1.616                                                                              a-f                                                                               4 0.06                                                                               g  4 0.38                                                                               e-g                 16 + 4                                                                               4 6.3  a-e                                                                               4 0.0  e  4 308.3                                                                              a-e                                                                               3 1.526                                                                              c-f                                                                               4 1.06                                                                               e-g                                                                               4 0.56                                                                               e-g                 16 + 8                                                                               4 0.0  e  4 0.0  e  4 256.4                                                                              e  4 1.732                                                                              a-b                                                                               4 0.00                                                                               g  4 0.00                                                                               g                   __________________________________________________________________________

                                      EXPERIMENT NO. 32                            __________________________________________________________________________     Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of                                          broiler cockerels inoculated with E. tenella and E. maxima                                                                 Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     4 0.0  e  4 0.0  a  4 318.6                                                                              a  4 1.467                                                                              b-e                                                                               4 1.63                                                                               i-j                                                                               4 0.13                                                                               g                   IC                                                                             0     4 6.3  a-c                                                                               4 0.0  a  4 274.0                                                                              b-f                                                                               3 1.588                                                                              a-e                                                                               4 8.29                                                                               a  4 3.29                                                                               a                   A80190 +                                                                       Example                                                                        No. 57                                                                         2 + 2 4 0.0  e  4 0.0  a  4 258.3                                                                              f  4 1.599                                                                              a-c                                                                               4 7.88                                                                               a-b                                                                               4 2.94                                                                               a-c                 2 + 4 4 0.0  e  4 0.0  a  4 256.2                                                                              f  4 1.651                                                                              a  4 6.31                                                                               a-f                                                                               4 3.31                                                                               a                   2 + 8 4 0.0  e  4 0.0  a  4 269.0                                                                              d-f                                                                               4 1.582                                                                              a-e                                                                               4 5.13                                                                               a-h                                                                               4 2.50                                                                               a-d                 4 + 2 4 6.3  a-c                                                                               4 0.0  a  4 272.1                                                                              c-f                                                                               3 1.611                                                                              a-b                                                                               4 7.31                                                                               a-c                                                                               4 3.56                                                                               a                   4 + 4 4 0.0  e  4 0.0  a  4 292.7                                                                              a-f                                                                               4 1.528                                                                              a-e                                                                               4 6.25                                                                               a-f                                                                               4 3.19                                                                               a-b                 4 + 8 4 0.0  e  4 0.0  a  4 280.0                                                                              b-f                                                                               4 1.578                                                                              a-e                                                                               4 4.50                                                                               c-i                                                                               4 2.06                                                                               b-d                 8 + 2 4 0.0  e  4 0.0  a  4 265.8                                                                              e-f                                                                               4 1.577                                                                              a-e                                                                               4 7.44                                                                               a-c                                                                               4 3.00                                                                               a-c                 8 + 4 4 0.0  e  4 0.0  a  4 275.5                                                                              b-f                                                                               4 1.542                                                                              a-e                                                                               4 6.13                                                                               a-f                                                                               4 2.88                                                                               a-c                 8 + 8 4 0.0  e  4 0.0  a  4 274.7                                                                              b-f                                                                               4 1.571                                                                              a-e                                                                               4 3.69                                                                               d-j                                                                               4 0.94                                                                               e-g                 16 + 2                                                                               4 0.0  e  4 0.0  a  4 285.9                                                                              a-f                                                                               4 1.560                                                                              a-e                                                                               4 7.06                                                                               a-c                                                                               4 3.00                                                                               a-c                 16 + 4                                                                               4 0.0  e  4 0.0  a  4 296.9                                                                              a-e                                                                               4 1.512                                                                              a-e                                                                               4 5.44                                                                               a-g                                                                               4 2.06                                                                               b-d                 16 + 8                                                                               4 0.0  e  4 0.0  a  4 286.8                                                                              a-f                                                                               4 1.566                                                                              a-e                                                                               4 3.50                                                                               e-j                                                                               4 0.88                                                                               e-g                 A82810 +                                                                       Example                                                                        No. 57                                                                         2 + 2 4 0.0  e  4 0.0  a  4 289.0                                                                              a-f                                                                               4 1.573                                                                              a-e                                                                               4 7.13                                                                               a-c                                                                               4 3.38                                                                               a                   2 + 4 4 0.0  e  4 0.0  a  4 301.3                                                                              a-e                                                                               4 1.505                                                                              a-e                                                                               4 6.50                                                                               a-e                                                                               4 3.25                                                                               a                   2 + 8 4 0.0  e  4 0.0  a  4 285.5                                                                              a-f                                                                               4 1.595                                                                              a-e                                                                               4 3.19                                                                               f-j                                                                               4 0.88                                                                               e-g                 4 + 2 4 0.0  e  4 0.0  a  4 306.3                                                                              a-d                                                                               4 1.490                                                                              a-e                                                                               4 6.81                                                                               a-d                                                                               4 3.31                                                                               a                   4 + 4 4 0.0  e  4 0.0  a  4 309.1                                                                              a-c                                                                               4 1.455                                                                              c-e                                                                               4 4.81                                                                               b-h                                                                               4 1.63                                                                               d-f                 4 + 8 4 0.0  e  4 0.0  a  4 287.3                                                                              a-f                                                                               4 1.488                                                                              a-e                                                                               4 2.88                                                                               g-j                                                                               4 0.63                                                                               f-g                 8 + 2 4 6.3  a-c                                                                               4 0.0  a  4 311.7                                                                              a-b                                                                               3 1.450                                                                              d-e                                                                               4 6.04                                                                               a-f                                                                               4 1.88                                                                               c-e                 8 + 4 4 0.0  e  4 0.0  a  4 305.3                                                                              a-d                                                                               4 1.445                                                                              e  4 3.75                                                                               d-j                                                                               4 0.81                                                                               e-g                 8 + 8 4 0.0  e  4 0.0  a  4 281.6                                                                              a-f                                                                               4 1.513                                                                              a-e                                                                               4 1.56                                                                               i-j                                                                               4 0.56                                                                               f-g                 16 + 2                                                                               4 0.0  e  4 0.0  a  4 290.0                                                                              a-f                                                                               4 1.535                                                                              a-e                                                                               4 3.81                                                                               d-j                                                                               4 0.56                                                                               f-g                 16 + 4                                                                               4 0.0  e  4 0.0  a  4 282.4                                                                              a-f                                                                               4 1.568                                                                              a-e                                                                               4 2.06                                                                               h-j                                                                               4 0.50                                                                               f-g                 16 + 8                                                                               4 0.0  e  4 0.0  a  4 265.6                                                                              e-f                                                                               4 1.596                                                                              a-d                                                                               4 0.75                                                                               j  4 0.00                                                                               g                   __________________________________________________________________________

                                      EXPERIMENT NO. 33                            __________________________________________________________________________     Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of                                          broiler cockerels inoculated with E. tenella and E. maxima                                                                 Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     4 0.0  e  4 0.0  a  4 341.1                                                                              a  4 1.395                                                                              c-e                                                                               4 2.00                                                                               d-f                                                                               4 0.06                                                                               f                   IC                                                                             0     4 0.0  e  4 0.0  a  4 314.8                                                                              a-d                                                                               4 1.439                                                                              a-e                                                                               4 6.44                                                                               a  4 2.44                                                                               a-b                 A80190                                                                         10    4 0.0  e  4 0.0  a  4 325.6                                                                              a-c                                                                               4 1.429                                                                              a-e                                                                               4 5.88                                                                               a-b                                                                               4 2.69                                                                               a                   20    4 0.0  e  4 0.0  a  4 310.7                                                                              a-e                                                                               4 1.377                                                                              e  4 5.69                                                                               a-b                                                                               4 2.44                                                                               a-b                 30    4 0.0  e  4 0.0  a  4 294.6                                                                              b-e                                                                               4 1.430                                                                              a-e                                                                               4 5.56                                                                               a-c                                                                               4 2.31                                                                               a-b                 40    4 0.0  e  4 0.0  a  4 308.6                                                                              a-e                                                                               4 1.436                                                                              a-e                                                                               4 4.69                                                                               a-f                                                                               4 2.06                                                                               a-b                 Example                                                                        No. 57                                                                         2     4 0.0  e  4 0.0  a  4 296.5                                                                              a-e                                                                               4 1.466                                                                              a-e                                                                               4 5.31                                                                               a-d                                                                               4 2.19                                                                               a-b                 4     4 0.0  e  4 0.0  a  4 283.2                                                                              b-e                                                                               4 1.500                                                                              a-e                                                                               4 5.81                                                                               a-b                                                                               4 2.19                                                                               a-b                 6     4 0.0  e  4 0.0  a  4 290.4                                                                              b-e                                                                               4 1.470                                                                              a-e                                                                               4 6.50                                                                               a  4 2.31                                                                               a-b                 8     4 0.0  e  4 0.0  a  4 267.3                                                                              e  4 1.593                                                                              a  4 3.88                                                                               a-f                                                                               4 1.25                                                                               b-f                 A80190 +                                                                       Example                                                                        No. 57                                                                         10 + 2                                                                               4 0.0  e  4 0.0  a  4 314.7                                                                              a-d                                                                               4 1.437                                                                              a-e                                                                               4 5.44                                                                               a-c                                                                               4 2.19                                                                               a-b                 10 + 4                                                                               4 0.0  e  4 0.0  a  4 296.7                                                                              a-e                                                                               4 1.481                                                                              a-e                                                                               4 5.00                                                                               a-e                                                                               4 2.13                                                                               a-b                 10 + 6                                                                               4 0.0  e  4 0.0  a  4 295.1                                                                              b-e                                                                               4 1.550                                                                              a-c                                                                               4 4.75                                                                               a-f                                                                               4 2.13                                                                               a-b                 10 + 8                                                                               4 0.0  e  4 0.0  a  4 280.6                                                                              c-e                                                                               4 1.566                                                                              a-b                                                                               4 2.69                                                                               b-f                                                                               4 0.56                                                                               c-f                 20 + 2                                                                               4 0.0  e  4 0.0  a  4 305.7                                                                              a-e                                                                               4 1.408                                                                              b-e                                                                               4 4.81                                                                               a-f                                                                               4 2.19                                                                               a-b                 20 + 4                                                                               4 0.0  e  4 0.0  a  4 304.9                                                                              a-e                                                                               4 1.465                                                                              a-e                                                                               4 3.50                                                                               a-f                                                                               4 1.44                                                                               a-e                 20 + 6                                                                               4 0.0  e  4 0.0  a  4 298.7                                                                              a-e                                                                               4 1.452                                                                              a-e                                                                               4 4.44                                                                               a-f                                                                               4 1.50                                                                               a-d                 20 + 8                                                                               4 0.0  e  4 0.0  a  4 288.0                                                                              b-e                                                                               4 1.515                                                                              a-e                                                                               4 2.56                                                                               b-f                                                                               4 0.19                                                                               f                   30 + 2                                                                               4 0.0  e  4 0.0  a  4 308.7                                                                              a-e                                                                               4 1.414                                                                              a-e                                                                               4 4.44                                                                               a-f                                                                               4 1.69                                                                               a-c                 30 + 4                                                                               4 0.0  e  4 0.0  a  4 297.7                                                                              a-e                                                                               4 1.456                                                                              a-e                                                                               4 4.06                                                                               a-f                                                                               4 0.75                                                                               c-f                 30 + 6                                                                               4 0.0  e  4 0.0  a  4 296.6                                                                              a-e                                                                               4 1.484                                                                              a-e                                                                               4 2.19                                                                               c-f                                                                               4 0.44                                                                               d-f                 30 + 8                                                                               4 0.0  e  4 0.0  a  4 280.2                                                                              d-e                                                                               4 1.494                                                                              a-e                                                                               4 1.50                                                                               f  4 0.13                                                                               f                   40 + 2                                                                               4 0.0  e  4 0.0  a  4 327.7                                                                              a-b                                                                               4 1.377                                                                              e  4 4.50                                                                               a-f                                                                               4 0.81                                                                               c-f                 40 + 4                                                                               4 6.3  a  4 0.0  a  4 302.8                                                                              a-e                                                                               3 1.450                                                                              a-e                                                                               4 3.60                                                                               a-f                                                                               4 0.69                                                                               c-f                 40 + 6                                                                               4 0.0  e  4 0.0  a  4 301.6                                                                              a-e                                                                               4 1.537                                                                              a-d                                                                               4 1.88                                                                               e-f                                                                               4 0.31                                                                               e-f                 40 + 8                                                                               4 0.0  e  4 0.0  a  4 294.0                                                                              b-e                                                                               4 1.533                                                                              a-e                                                                               4 1.63                                                                               e-f                                                                               4 0.25                                                                               f                   __________________________________________________________________________

                                      EXPERIMENT NO. 34                            __________________________________________________________________________     Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of                                          broiler cockerels inoculated with E. tenella and E. acervulina                                                             Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     4 0.0  a  4 0.0  a  4 326.7                                                                              a  4 1.352                                                                              d  4 0.00                                                                               f  4 0.00                                                                               e                   IC                                                                             0     4 0.0  a  4 0.0  a  4 279.3                                                                              b-e                                                                               4 1.613                                                                              a-c                                                                               4 5.88                                                                               a  4 3.50                                                                               a-b                 A80190                                                                         20    4 0.0  a  4 0.0  a  4 299.3                                                                              a-e                                                                               4 1.549                                                                              a-c                                                                               4 3.75                                                                               c  4 3.50                                                                               a-b                 40    4 0.0  a  4 0.0  a  4 317.5                                                                              a-b                                                                               4 1.447                                                                              b-d                                                                               4 0.94                                                                               e-f                                                                               4 1.13                                                                               d                   60    4 6.3  a  4 0.0  a  4 287.7                                                                              a-e                                                                               3 1.547                                                                              a-c                                                                               4 0.35                                                                               f  4 0.58                                                                               d-e                 Example                                                                        No. 57                                                                         2     4 0.0  a  4 0.0  a  4 266.2                                                                              c-e                                                                               4 1.625                                                                              a-b                                                                               4 5.75                                                                               a  4 3.63                                                                               a                   3     4 0.0  a  4 0.0  a  4 274.2                                                                              b-e                                                                               4 1.635                                                                              a  4 5.19                                                                               a-b                                                                               4 3.44                                                                               a-b                 4     4 6.3  a  4 6.3  a  4 262.1                                                                              d-e                                                                               3 1.617                                                                              a-c                                                                               4 5.56                                                                               a  4 3.19                                                                               a-b                 5     4 0.0  a  4 0.0  a  4 267.3                                                                              c-e                                                                               4 1.579                                                                              a-c                                                                               4 4.63                                                                               b  4 3.50                                                                               a-b                 A80190 +                                                                       Example                                                                        No. 57                                                                         20 + 2                                                                               4 0.0  a  4 0.0  a  4 295.5                                                                              a-e                                                                               4 1.507                                                                              a-d                                                                               4 2.19                                                                               d  4 3.56                                                                               a-b                 20 + 3                                                                               4 6.3  a  4 0.0  a  4 294.2                                                                              a-e                                                                               3 1.493                                                                              a-d                                                                               4 1.50                                                                               d-e                                                                               4 2.65                                                                               b-c                 20 + 4                                                                               4 0.0  a  4 0.0  a  4 312.6                                                                              a-c                                                                               4 1.450                                                                              b-d                                                                               4 1.19                                                                               e-f                                                                               4 2.06                                                                               c                   20 + 5                                                                               4 0.0  a  4 0.0  a  4 297.3                                                                              a-e                                                                               4 1.472                                                                              a-d                                                                               4 0.38                                                                               f  4 1.19                                                                               d                   40 + 2                                                                               4 0.0  a  4 0.0  a  4 311.5                                                                              a-c                                                                               4 1.432                                                                              c-d                                                                               4 0.19                                                                               f  4 0.69                                                                               d-e                 40 + 3                                                                               4 0.0  a  4 0.0  a  4 306.4                                                                              a-d                                                                               4 1.448                                                                              b-d                                                                               4 0.63                                                                               e-f                                                                               4 0.50                                                                               d-e                 40 + 4                                                                               4 0.0  a  4 0.0  a  4 271.3                                                                              b-e                                                                               4 1.580                                                                              a-c                                                                               4 0.31                                                                               f  4 0.44                                                                               d-e                 40 + 5                                                                               4 0.0  a  4 0.0  a  4 297.4                                                                              a-e                                                                               4 1.436                                                                              c-d                                                                               4 0.13                                                                               f  4 0.25                                                                               d-e                 60 + 2                                                                               4 12.5 a  4 0.0  a  4 279.5                                                                              b-e                                                                               2 1.381                                                                              c-d                                                                               4 0.00                                                                               f  4 0.13                                                                               e                   60 + 3                                                                               4 6.3  a  4 0.0  a  4 277.9                                                                              b-e                                                                               3 1.555                                                                              a-c                                                                               4 0.13                                                                               f  4 0.15                                                                               e                   60 + 4                                                                               4 0.0  a  4 0.0  a  4 254.1                                                                              e  4 1.634                                                                              a  4 0.00                                                                               f  4 0.06                                                                               e                   60 + 5                                                                               4 0.0  a  4 0.0  a  4 260.6                                                                              d-e                                                                               4 1.590                                                                              a-c                                                                               4 0.00                                                                               f  4 0.00                                                                               e                   __________________________________________________________________________

                                      EXPERIMENT NO. 35                            __________________________________________________________________________     Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of                                          broiler cockerels inoculated with E. tenella and E. maxima                                                                 Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     4 0.0  b  4 0.0  a  4 332.1                                                                              a-c                                                                               4 1.482                                                                              a-c                                                                               4 0.81                                                                               e  4 0.00                                                                               f                   IC                                                                             0     4 0.0  b  4 0.0  a  4 308.2                                                                              a-d                                                                               4 1.523                                                                              a-c                                                                               4 7.13                                                                               a  4 2.56                                                                               a-b                 A80190                                                                         20    4 0.0  b  4 0.0  a  4 312.4                                                                              a-d                                                                               4 1.544                                                                              a-c                                                                               4 5.81                                                                               a-b                                                                               4 2.13                                                                               b-c                 40    4 0.0  b  4 0.0  a  4 338.1                                                                              a-b                                                                               4 1.405                                                                              b-c                                                                               4 4.06                                                                               b-d                                                                               4 1.19                                                                               d-e                 60    4 0.0  b  4 0.0  a  4 277.1                                                                              d  4 1.655                                                                              a  4 1.94                                                                               d-e                                                                               4 0.63                                                                               e-f                 Example                                                                        No. 57                                                                         2     4 18.8 a  4 12.5 a  4 282.4                                                                              d  2 1.609                                                                              a-c                                                                               4 6.65                                                                               a-b                                                                               4 3.27                                                                               a                   3     4 6.3  a-b                                                                               4 6.3  a  4 275.5                                                                              d  3 1.526                                                                              a-c                                                                               4 6.56                                                                               a-b                                                                               4 2.75                                                                               a-b                 4     4 0.0  b  4 0.0  a  4 285.3                                                                              d  4 1.554                                                                              a-c                                                                               4 5.81                                                                               a-b                                                                               4 2.38                                                                               b                   5     4 0.0  b  4 0.0  a  4 296.8                                                                              b-d                                                                               4 1.542                                                                              a-c                                                                               4 5.69                                                                               a-b                                                                               4 2.06                                                                               b-d                 A80190 +                                                                       Example                                                                        No. 57                                                                         20 + 2                                                                               4 6.3  a-b                                                                               4 0.0  a  4 314.7                                                                              a-d                                                                               3 1.523                                                                              a-c                                                                               4 5.06                                                                               a-c                                                                               4 1.92                                                                               b-d                 20 + 3                                                                               4 0.0  b  4 0.0  a  4 312.2                                                                              a-d                                                                               4 1.501                                                                              a-c                                                                               4 4.94                                                                               a-c                                                                               4 1.81                                                                               b-d                 20 + 4                                                                               4 0.0  b  4 0.0  a  4 318.4                                                                              a-d                                                                               4 1.493                                                                              a-c                                                                               4 4.25                                                                               a-d                                                                               4 1.25                                                                               c-e                 20 + 5                                                                               4 0.0  b  4 0.0  a  4 309.1                                                                              a-d                                                                               4 1.493                                                                              a-c                                                                               4 2.88                                                                               c-e                                                                               4 0.81                                                                               e-f                 40 + 2                                                                               4 0.0  b  4 0.0  a  4 346.9                                                                              a  4 1.381                                                                              c  4 2.19                                                                               d-e                                                                               4 0.63                                                                               e-f                 40 + 3                                                                               4 0.0  b  4 0.0  a  4 313.5                                                                              a-d                                                                               4 1.500                                                                              a-c                                                                               4 2.06                                                                               d-e                                                                               4 0.31                                                                               e-f                 40 + 4                                                                               4 0.0  b  4 0.0  a  4 308.3                                                                              a-d                                                                               4 1.487                                                                              a-c                                                                               4 2.00                                                                               d-e                                                                               4 0.44                                                                               e-f                 40 + 5                                                                               4 0.0  b  4 0.0  a  4 289.5                                                                              c-d                                                                               4 1.536                                                                              a-c                                                                               4 1.13                                                                               e  4 0.13                                                                               f                   60 + 2                                                                               4 6.3  a-b                                                                               4 0.0  a  4 300.6                                                                              b-d                                                                               3 1.612                                                                              a-b                                                                               4 1.27                                                                               e  4 0.29                                                                               e-f                 60 + 3                                                                               4 0.0  b  4 0.0  a  4 296.1                                                                              b-d                                                                               4 1.546                                                                              a-c                                                                               4 0.56                                                                               e  4 0.25                                                                               e-f                 60 + 4                                                                               4 0.0  b  4 0.0  a  4 289.3                                                                              c-d                                                                               4 1.621                                                                              a  4 0.13                                                                               e  4 0.00                                                                               f                   60 + 5                                                                               4 0.0  b  4 0.0  a  4 275.6                                                                              d  4 1.624                                                                              a  4 0.75                                                                               e  4 0.06                                                                               f                   __________________________________________________________________________

                                      EXPERIMENT NO. 36                            __________________________________________________________________________     Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of                                          broiler cockerels inoculated with E. tenella and E. acervulina                                                             Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     4 6.3  a  4 0.0  a  4 318.4                                                                              a  4 1.358                                                                              d  4 0.00                                                                               f  4 0.00                                                                               e                   IC                                                                             0     4 0.0  a  4 0.0  a  4 257.7                                                                              c-d                                                                               4 1.676                                                                              a-b                                                                               4 5.75                                                                               a  4 3.50                                                                               a                   Monensin                                                                       20    4 6.3  a  4 0.0  a  4 277.0                                                                              a-d                                                                               4 1.604                                                                              a-c                                                                               4 4.44                                                                               a-b                                                                               4 3.21                                                                               a-b                 40    4 0.0  a  4 0.0  a  4 280.0                                                                              a-d                                                                               4 1.550                                                                              a-d                                                                               4 3.38                                                                               b-c                                                                               4 3.38                                                                               a                   60    4 0.0  a  4 0.0  a  4 281.8                                                                              a-d                                                                               4 1.527                                                                              a-d                                                                               4 3.25                                                                               b-c                                                                               4 3.56                                                                               a                   80    4 0.0  a  4 0.0  a  4 306.3                                                                              a-b                                                                               4 1.445                                                                              c-d                                                                               4 2.25                                                                               c-e                                                                               4 3.19                                                                               a-b                 Example                                                                        No. 57                                                                         2     4 0.0  a  4 0.0  a  4 249.3                                                                              d  4 1.695                                                                              a  4 5.88                                                                               a  4 3.38                                                                               a                   4     4 0.0  a  4 0.0  a  4 270.2                                                                              b-d                                                                               4 1.594                                                                              a-c                                                                               4 5.31                                                                               a  4 2.81                                                                               a-c                 6     4 0.0  a  4 0.0  a  4 263.5                                                                              b-d                                                                               4 1.588                                                                              a-c                                                                               4 4.44                                                                               a-b                                                                               4 3.13                                                                               a-b                 Monen-                                                                         sin +                                                                          Example                                                                        No. 57                                                                         20 + 2                                                                               4 0.0  a  4 0.0  a  4 289.0                                                                              a-d                                                                               4 1.497                                                                              a-d                                                                               4 2.81                                                                               b-d                                                                               4 3.44                                                                               a                   20 + 4                                                                               4 0.0  a  4 0.0  a  4 291.9                                                                              a-d                                                                               4 1.450                                                                              c-d                                                                               4 3.25                                                                               b-c                                                                               4 3.13                                                                               a-b                 20 + 6                                                                               4 0.0  a  4 0.0  a  4 277.9                                                                              a-d                                                                               4 1.556                                                                              a-d                                                                               4 2.06                                                                               c-e                                                                               4 1.81                                                                               c-d                 40 + 2                                                                               4 0.0  a  4 0.0  a  4 289.8                                                                              a-d                                                                               4 1.492                                                                              a-d                                                                               4 2.94                                                                               b-d                                                                               4 3.19                                                                               a-b                 40 + 4                                                                               4 0.0  a  4 0.0  a  4 298.7                                                                              a-c                                                                               4 1.463                                                                              b-d                                                                               4 2.31                                                                               c-e                                                                               4 2.50                                                                               a-d                 40 + 6                                                                               4 0.0  a  4 0.0  a  4 285.0                                                                              a-d                                                                               4 1.515                                                                              a-d                                                                               4 1.19                                                                               d-f                                                                               4 2.38                                                                               a-d                 60 + 2                                                                               4 0.0  a  4 0.0  a  4 304.9                                                                              a-c                                                                               4 1.425                                                                              c-d                                                                               4 2.19                                                                               c-e                                                                               4 2.94                                                                               a-c                 60 + 4                                                                               4 0.0  a  4 0.0  a  4 289.7                                                                              a-d                                                                               4 1.470                                                                              b-d                                                                               4 2.13                                                                               c-e                                                                               4 2.69                                                                               a-c                 60 + 6                                                                               4 0.0  a  4 0.0  a  4 275.0                                                                              a-d                                                                               4 1.565                                                                              a-d                                                                               4 0.56                                                                               e-f                                                                               4 1.88                                                                               b-d                 80 + 2                                                                               4 0.0  a  4 0.0  a  4 293.5                                                                              a-d                                                                               4 1.470                                                                              b-d                                                                               4 1.88                                                                               c-e                                                                               4 3.50                                                                               a                   80 + 4                                                                               4 0.0  a  4 0.0  a  4 301.5                                                                              a-c                                                                               4 1.487                                                                              a-d                                                                               4 1.06                                                                               d-f                                                                               4 2.75                                                                               a-c                 80 + 6                                                                               4 0.0  a  4 0.0  a  4 286.9                                                                              a-d                                                                               4 1.460                                                                              b-d                                                                               4 0.63                                                                               e-f                                                                               4 1.50                                                                               d                   __________________________________________________________________________

                                      EXPERIMENT NO. 37                            __________________________________________________________________________     Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of                                          broiler cockerels inoculated with E. tenella and E. maxima                                                                 Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     4 0.0  b  4 0.0  b  4 322.4                                                                              a  4 1.473                                                                              g  4 0.00                                                                               e  4 0.00                                                                               b                   IC                                                                             0     4 43.8 a  4 43.8 a  4 145.9                                                                              g-h                                                                               4 2.438                                                                              b-c                                                                               4 8.06                                                                               a  4 3.94                                                                               a                   Monensin                                                                       20    4 37.5 a-b                                                                               4 37.5 a-b                                                                               4 165.9                                                                              f-h                                                                               4 2.364                                                                              b-d                                                                               4 8.13                                                                               a  4 3.81                                                                               a                   40    4 25.0 a-b                                                                               4 25.0 a-b                                                                               4 177.1                                                                              e-h                                                                               4 2.306                                                                              b-e                                                                               4 8.19                                                                               a  4 3.75                                                                               a                   60    4 6.3  a-b                                                                               4 6.3  a-b                                                                               4 180.6                                                                              e-h                                                                               4 2.252                                                                              b-f                                                                               4 7.63                                                                               a  4 3.63                                                                               a                   80    4 18.8 a-b                                                                               4 18.8 a-b                                                                               4 162.1                                                                              f-h                                                                               4 2.126                                                                              b-f                                                                               4 7.56                                                                               a  4 3.81                                                                               a                   Example                                                                        No. 57                                                                         2     4 43.8 a  4 43.8 a  4 141.8                                                                              g-h                                                                               4 2.623                                                                              a-b                                                                               4 7.69                                                                               a  4 3.81                                                                               a                   4     4 37.5 a-b                                                                               4 37.5 a-b                                                                               4 172.8                                                                              f-h                                                                               4 2.310                                                                              b-e                                                                               4 6.44                                                                               a-d                                                                               4 3.88                                                                               a                   6     4 12.5 a-b                                                                               4 12.5 a-b                                                                               4 179.1                                                                              e-h                                                                               4 2.169                                                                              b-f                                                                               4 7.31                                                                               a-b                                                                               4 3.69                                                                               a                   Monen-                                                                         sin +                                                                          Example                                                                        No. 57                                                                         20 + 2                                                                               4 12.5 a-b                                                                               4 12.5 a-b                                                                               4 133.7                                                                              h  4 2.892                                                                              a  4 7.94                                                                               a  4 3.94                                                                               a                   20 + 4                                                                               4 18.8 a-b                                                                               4 18.8 a-b                                                                               4 194.0                                                                              d-h                                                                               4 2.128                                                                              b-f                                                                               4 6.94                                                                               a-c                                                                               4 3.94                                                                               a                   20 + 6                                                                               4 12.5 a-b                                                                               4 12.5 a-b                                                                               4 221.9                                                                              b-f                                                                               4 1.815                                                                              c-g                                                                               4 6.81                                                                               a-c                                                                               4 3.63                                                                               a                   40 + 2                                                                               4 6.3  a-b                                                                               4 6.3  a-b                                                                               4 180.0                                                                              e-h                                                                               4 2.182                                                                              b-f                                                                               4 7.94                                                                               a  4 3.75                                                                               a                   40 + 4                                                                               4 6.3  a-b                                                                               4 6.3  a-b                                                                               4 205.5                                                                              c-g                                                                               4 2.099                                                                              b-f                                                                               4 7.69                                                                               a  4 4.00                                                                               a                   40 + 6                                                                               4 6.3  a-b                                                                               4 6.3  a-b                                                                               4 247.9                                                                              b-d                                                                               4 1.716                                                                              d-g                                                                               4 6.25                                                                               a-d                                                                               4 3.81                                                                               a                   60 + 2                                                                               4 12.5 a-b                                                                               4 12.5 a-b                                                                               4 228.2                                                                              b-f                                                                               4 1.815                                                                              c-g                                                                               4 7.19                                                                               a-b                                                                               4 3.94                                                                               a                   60 + 4                                                                               4 12.5 a-b                                                                               4 6.3  a-b                                                                               4 243.8                                                                              b-e                                                                               4 1.770                                                                              d-g                                                                               4 6.90                                                                               a-c                                                                               4 3.75                                                                               a                   60 + 6                                                                               4 6.3  a-b                                                                               4 6.3  a-b                                                                               4 266.7                                                                              b-c                                                                               4 1.651                                                                              e-g                                                                               4 5.06                                                                               c-d                                                                               4 3.94                                                                               a                   80 + 2                                                                               4 31.3 a-b                                                                               4 31.3 a-b                                                                               4 209.9                                                                              b-g                                                                               4 1.994                                                                              b-g                                                                               4 6.94                                                                               a-c                                                                               4 3.81                                                                               a                   80 + 4                                                                               4 0.0  b  4 0.0  b  4 261.1                                                                              b-c                                                                               4 1.612                                                                              f-g                                                                               4 5.50                                                                               b-d                                                                               4 3.81                                                                               a                   80 + 6                                                                               4 0.0  b  4 0.0  b  4 274.5                                                                              b  4 1.653                                                                              e-g                                                                               4 4.94                                                                               d  4 3.69                                                                               a                   __________________________________________________________________________

                                      EXPERIMENT NO. 38                            __________________________________________________________________________     Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of                                          broiler cockerels inoculated with E. acervulina, E. tenella and E.             maxima                                                                                                                     Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     4 0.0  a  4 0.0  a  4 321.1                                                                              a-b                                                                               4 1.488                                                                              b  4 0.00                                                                               b  4 0.00                                                                               c                   IC                                                                             0     4 6.3  a  4 0.0  a  4 214.4                                                                              c  4 1.960                                                                              a  4 8.00                                                                               a  4 3.73                                                                               a                   A80190                                                                         30    4 0.0  a  4 0.0  a  4 334.0                                                                              a  4 1.437                                                                              b  4 0.25                                                                               b  4 0.25                                                                               c                   40    4 0.0  a  4 0.0  a  4 330.8                                                                              a  4 1.430                                                                              b  4 0.25                                                                               b  4 0.00                                                                               c                   50    4 0.0  a  4 0.0  a  4 306.1                                                                              a-b                                                                               4 1.480                                                                              b  4 0.00                                                                               b  4 0.00                                                                               c                   Example                                                                        No. 57                                                                         2     4 6.3  a  4 6.3  a  4 223.5                                                                              c  4 1.852                                                                              a  4 8.06                                                                               a  4 3.50                                                                               a-b                 3     4 6.3  a  4 0.0  a  4 218.0                                                                              c  4 1.897                                                                              a  4 8.44                                                                               a  4 3.08                                                                               b                   4     4 0.0  a  4 0.0  a  4 228.1                                                                              c  4 1.892                                                                              a  4 8.06                                                                               a  4 3.69                                                                               a                   A80190 +                                                                       Example                                                                        No. 57                                                                         30 + 2                                                                               4 0.0  a  4 0.0  a  4 324.7                                                                              a-b                                                                               4 1.407                                                                              b  4 0.00                                                                               b  4 0.25                                                                               c                   30 + 3                                                                               4 0.0  a  4 0.0  a  4 315.3                                                                              a-b                                                                               4 1.459                                                                              b  4 0.00                                                                               b  4 0.13                                                                               c                   30 + 4                                                                               4 0.0  a  4 0.0  a  4 317.1                                                                              a-b                                                                               4 1.424                                                                              b  4 0.00                                                                               b  4 0.00                                                                               c                   40 + 2                                                                               4 0.0  a  4 0.0  a  4 329.2                                                                              a  4 1.414                                                                              b  4 0.00                                                                               b  4 0.00                                                                               c                   40 + 3                                                                               4 0.0  a  4 0.0  a  4 292.5                                                                              a-b                                                                               4 1.503                                                                              b  4 0.00                                                                               b  4 0.00                                                                               c                   40 + 4                                                                               4 0.0  a  4 0.0  a  4 285.1                                                                              b  4 1.562                                                                              b  4 0.00                                                                               b  4 0.25                                                                               c                   50 + 2                                                                               4 0.0  a  4 0.0  a  4 304.3                                                                              a-b                                                                               4 1.497                                                                              b  4 0.00                                                                               b  4 0.00                                                                               c                   50 + 3                                                                               4 0.0  a  4 0.0  a  4 304.4                                                                              a-b                                                                               4 1.487                                                                              b  4 0.00                                                                               b  4 0.00                                                                               c                   50 + 4                                                                               4 0.0  a  4 0.0  a  4 303.6                                                                              a-b                                                                               4 1.522                                                                              b  4 0.00                                                                               b  4 0.00                                                                               c                   __________________________________________________________________________

                                      EXPERIMENT NO. 39                            __________________________________________________________________________     Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of                                          broiler cockerels inoculated with E. acervulina, E. maxima and E.              tenella                                                                                                                    Lesion Scores                      Treatment                                                                            Mortality Mean      Wt. Gain Feed/Gain                                                                               Intestinal                                                                              Cecal                     PPM   # Total % # % DTC   # Mean   # Mean   # Mean   # Mean                    __________________________________________________________________________     NC                                                                             0     4 0.0  a  4 0.0  b  4 316.7                                                                              a  4 1.414                                                                              b  4 0.00                                                                               d  4 0.00                                                                               f                   IC                                                                             0     4 25.0 a  4 25.0 a  4 169.3                                                                              c  4 2.188                                                                              a  4 8.75                                                                               a  4 3.81                                                                               a                   A80190                                                                         30    4 0.0  a  4 0.0  b  4 256.0                                                                              b  4 1.586                                                                              b  4 7.63                                                                               a  4 3.69                                                                               a                   40    4 0.0  a  4 0.0  b  4 274.8                                                                              a-b                                                                               4 1.572                                                                              b  4 5.31                                                                               b  4 2.75                                                                               a-d                 50    4 6.3  a  4 0.0  b  4 290.1                                                                              a-b                                                                               4 1.487                                                                              b  4 2.90                                                                               b-d                                                                               4 2.17                                                                               b-e                 Example                                                                        No. 57                                                                         2     4 12.5 a  4 12.5 a-b                                                                               4 185.7                                                                              c  4 2.039                                                                              a  4 8.50                                                                               a  4 3.50                                                                               a-b                 3     4 18.8 a  4 12.5 a-b                                                                               4 189.1                                                                              c  4 2.091                                                                              a  4 8.65                                                                               a  4 3.75                                                                               a                   4     4 18.8 a  4 18.8 a-b                                                                               4 161.3                                                                              c  4 2.222                                                                              a  4 8.25                                                                               a  4 3.81                                                                               a                   A80190 +                                                                       Example                                                                        No. 57                                                                         30 + 2                                                                               4 0.0  a  4 0.0  b  4 269.6                                                                              a-b                                                                               4 1.597                                                                              b  4 5.25                                                                               b  4 3.06                                                                               a-c                 30 + 3                                                                               4 0.0  a  4 0.0  b  4 295.6                                                                              a-b                                                                               4 1.477                                                                              b  4 3.38                                                                               b-c                                                                               4 2.81                                                                               a-d                 30 + 4                                                                               4 0.0  a  4 0.0  b  4 294.5                                                                              a-b                                                                               4 1.481                                                                              b  4 1.19                                                                               c-d                                                                               4 1.75                                                                               c-e                 40 + 2                                                                               4 0.0  a  4 0.0  b  4 269.1                                                                              a-b                                                                               4 1.647                                                                              b  4 3.50                                                                               b-c                                                                               4 2.50                                                                               a-d                 40 + 3                                                                               4 12.5 a  4 6.3  a-b                                                                               4 290.7                                                                              a-b                                                                               4 1.489                                                                              b  4 1.60                                                                               c-d                                                                               4 1.56                                                                               d-e                 40 + 4                                                                               4 0.0  a  4 0.0  b  4 300.0                                                                              a-b                                                                               4 1.493                                                                              b  4 0.00                                                                               d  4 1.44                                                                               d-e                 50 + 2                                                                               4 0.0  a  4 0.0  b  4 266.7                                                                              a-b                                                                               4 1.584                                                                              b  4 0.19                                                                               d  4 0.88                                                                               e-f                 50 + 3                                                                               4 0.0  a  4 0.0  b  4 268.7                                                                              a-b                                                                               4 1.608                                                                              b  4 0.25                                                                               d  4 0.75                                                                               e-f                 50 + 4                                                                               4 0.0  a  4 0.0  b  4 273.4                                                                              a-b                                                                               4 1.556                                                                              b  4 0.00                                                                               d  4 0.88                                                                               e-f                 __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 40                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                     Lesion Scores                                Treatment                                                                              Mortality                                                                           Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                           Cecal                                  PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean                                                                               # Mean                                 __________________________________________________________________________     NC                                                                             0     3 0.0 a                                                                               3 0.0 a                                                                               3 333.5 a                                                                             3 1.400 d                                                                             3 0.00 c                                                                             3 0.00 g                               IC                                                                             0     3 0.0 a                                                                               3 0.0 a                                                                               3 235.5 e-f                                                                           3 1.743 c                                                                             3 8.58 a                                                                             3 3.33 a                               A204                                                                           2     3 0.0 a                                                                               3 0.0 a                                                                               3 247.8 d-e                                                                           3 1.670 c                                                                             3 4.33 b                                                                             3 3.33 a                               4     3 0.0 a                                                                               3 0.0 a                                                                               3 278.9 b-d                                                                           3 1.680 c                                                                             3 3.83 b                                                                             3 3.33 a                               8     3 0.0 a                                                                               3 0.0 a                                                                               3 312.7 a-b                                                                           3 1.487 c-d                                                                           3 0.17 c                                                                             3 3.00 a                               Example No. 39                                                                 2     3 0.0 a                                                                               3 0.0 a                                                                               3 269.0 c-d                                                                           3 1.653 c-d                                                                           3 0.33 c                                                                             3 3.50 a                               4     3 8.3 a                                                                               3 0.0 a                                                                               3 271.7 b-d                                                                           2 1.612 c-d                                                                           3 0.08 c                                                                             3 1.89 b-c                             8     3 0.0 a                                                                               3 0.0 a                                                                               3 207.7 f-g                                                                           3 1.936 b                                                                             3 0.00 c                                                                             3 0.92 d-f                             A204 + Example No. 39                                                          2 + 2 3 0.0 a                                                                               3 0.0 a                                                                               3 300.6 a-c                                                                           3 1.554 c-d                                                                           3 0.00 c                                                                             3 3.17 a                               2 + 4 3 0.0 a                                                                               3 0.0 a                                                                               3 280.2 b-d                                                                           3 1.592 c-d                                                                           3 0.00 c                                                                             3 1.50 c-d                             2 + 8 3 0.0 a                                                                               3 0.0 a                                                                               3 205.4 f-g                                                                           3 2.008 a-b                                                                           3 0.00 c                                                                             3 0.67 e-g                             4 + 2 3 0.0 a                                                                               3 0.0 a                                                                               3 286.3 b-d                                                                           3 1.553 c-d                                                                           3 0.00 c                                                                             3 2.17 b                               4 + 4 3 0.0 a                                                                               3 0.0 a                                                                               3 279.3 b-d                                                                           3 1.573 c-d                                                                           3 0.00 c                                                                             3 1.17 d-e                             4 + 8 3 0.0 a                                                                               3 0.0 a                                                                               3 195.0 g                                                                             3 1.984 a-b                                                                           3 0.00 c                                                                             3 0.17 f-g                             8 + 2 3 0.0 a                                                                               3 0.0 a                                                                               3 308.8 a-c                                                                           3 1.491 c-d                                                                           3 0.00 c                                                                             3 0.67 e-g                             8 + 4 3 0.0 a                                                                               3 0.0 a                                                                               3 292.3 b-c                                                                           3 1.596 c-d                                                                           3 0.00 c                                                                             3 0.33 f-g                             8 + 8 3 8.3 a                                                                               3 0.0 a                                                                               3 199.3 g                                                                             2 2.187 a                                                                             3 0.00 c                                                                             3 0.00 g                               __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 41                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                     Lesion Scores                                Treatment                                                                              Mortality                                                                           Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                           Cecal                                  PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean                                                                               # Mean                                 __________________________________________________________________________     NC                                                                             0     3 0.0 a                                                                               3 0.0 a                                                                               3 308.8 a                                                                             3 1.485 b                                                                             3 0.00 c                                                                             3 0.00 b                               IC                                                                             0     3 0.0 a                                                                               3 0.0 a                                                                               3 247.1 c-e                                                                           3 1.722 a-b                                                                           3 5.25 a                                                                             3 3.42 a                               A82810                                                                         1     3 0.0 a                                                                               3 0.0 a                                                                               3 238.1 c-e                                                                           3 1.797 a-b                                                                           3 2.75 b                                                                             3 3.17 a                               3     3 0.0 a                                                                               3 0.0 a                                                                               3 295.2 a-b                                                                           3 1.544 a-b                                                                           3 1.50 c                                                                             3 2.67 a                               5     3 8.3 a                                                                               3 0.0 a                                                                               3 301.8 a                                                                             2 1.466 b                                                                             3 0.17 c                                                                             3 0.42 b                               Example No. 39                                                                 2     3 0.0 a                                                                               3 0.0 a                                                                               3 235.3 c-e                                                                           3 1.789 a-b                                                                           3 1.25 c                                                                             3 3.42 a                               4     3 0.0 a                                                                               3 0.0 a                                                                               3 246.0 c-e                                                                           3 1.766 a-b                                                                           3 0.00 c                                                                             3 2.58 a                               8     3 16.7 a                                                                              3 0.0 a                                                                               3 219.3 d-e                                                                           2 1.875 a                                                                             3 0.00 c                                                                             3 0.83 b                               A82810 + Example No. 39                                                        1 + 2 3 0.0 a                                                                               3 0.0 a                                                                               3 290.9 a-b                                                                           3 1.499 b                                                                             3 0.33 c                                                                             3 2.75 a                               1 + 4 3 0.0 a                                                                               3 0.0 a                                                                               3 253.3 b-e                                                                           3 1.689 a-b                                                                           3 0.00 c                                                                             3 0.83 b                               1 + 8 3 0.0 a                                                                               3 0.0 a                                                                               3 221.4 d-e                                                                           3 1.902 a                                                                             3 0.00 c                                                                             3 0.00 b                               3 + 2 3 0.0 a                                                                               3 0.0 a                                                                               3 265.9 a-d                                                                           3 1.673 a-b                                                                           3 0.08 c                                                                             3 1.17 b                               3 + 4 3 25.0 a                                                                              3 0.0 a                                                                               3 269.3 a-c                                                                           1 1.537 a-b                                                                           3 0.00 c                                                                             3 0.42 b                               3 + 8 3 16.7 a                                                                              3 0.0 a                                                                               3 209.0 e                                                                             1 1.829 a-b                                                                           3 0.00 c                                                                             3 0.00 b                               5 + 2 3 0.0 a                                                                               3 0.0 a                                                                               3 292.1 a-b                                                                           3 1.551 a-b                                                                           3 0.00 c                                                                             3 0.33 b                               5 + 4 3 8.3 a                                                                               3 0.0 a                                                                               3 277.1 a-c                                                                           2 1.620 a-b                                                                           3 0.00 c                                                                             3 0.08 b                               5 + 8 3 0.0 a                                                                               3 0.0 a                                                                               3 230.9 c-e                                                                           3 1.790 a-b                                                                           3 0.00 c                                                                             3 0.00 b                               __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 42                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                     Lesion Scores                                Treatment                                                                              Mortality                                                                           Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                           Cecal                                  PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean                                                                               # Mean                                 __________________________________________________________________________     NC                                                                             0     3 0.0 a                                                                               3 0.0 a                                                                               3 261.9 a-b                                                                           3 1.467 b                                                                             3 0.00 b                                                                             3 0.00 c                               IC                                                                             0     3 16.7 a                                                                              3 0.0 a                                                                               3 227.8 a-c                                                                           1 1.735 a-b                                                                           3 4.50 a                                                                             3 2.67 a                               A82810                                                                         1     3 0.0 a                                                                               3 0.0 a                                                                               3 233.8 a-c                                                                           3 1.628 a-b                                                                           3 5.67 a                                                                             3 3.00 a                               3     3 0.0 a                                                                               3 0.0 a                                                                               3 270.5 a                                                                             3 1.507 b                                                                             3 1.08 b                                                                             3 1.83 a-b                             5     3 16.7 a                                                                              3 0.0 a                                                                               3 255.7 a-b                                                                           2 1.541 a-b                                                                           3 0.42 b                                                                             3 0.92 b-c                             Example No. 57                                                                 3     3 0.0 a                                                                               3 0.0 a                                                                               3 200.8 b-c                                                                           3 1.774 a-b                                                                           3 4.75 a                                                                             3 3.08 a                               6     3 0.0 a                                                                               3 0.0 a                                                                               3 218.5 a-c                                                                           3 1.730 a-b                                                                           3 1.00 b                                                                             3 2.50 a                               12    3 0.0 a                                                                               3 0.0 a                                                                               3 203.0 a-c                                                                           3 1.783 a-b                                                                           3 0.00 b                                                                             3 1.17 b-c                             A82810 + Example No. 57                                                        1 + 3 3 8.3 a                                                                               3 8.3 a                                                                               3 256.1 a-b                                                                           2 1.559 a-b                                                                           3 2.33 b                                                                             3 2.67 a                               1 + 6 3 0.0 a                                                                               3 0.0 a                                                                               3 255.8 a-b                                                                           3 1.561 a-b                                                                           3 0.25 b                                                                             3 1.17 b-c                             1 + 12                                                                               3 33.3 a                                                                              3 0.0 a                                                                               3 178.8 c                                                                             1 2.051 a                                                                             3 0.00 b                                                                             3 0.17 c                               3 + 3 3 0.0 a                                                                               3 0.0 a                                                                               3 261.0 a-b                                                                           3 1.524 a-b                                                                           3 0.25 b                                                                             3 1.00 b-c                             3 + 6 3 0.0 a                                                                               3 0.0 a                                                                               3 231.2 a-c                                                                           3 1.646 a-b                                                                           3 0.00 b                                                                             3 0.42 b-c                             3 + 12                                                                               3 0.0 a                                                                               3 0.0 a                                                                               3 217.3 a-c                                                                           3 1.716 a-b                                                                           3 0.00 b                                                                             3 0.08 c                               5 + 3 3 0.0 a                                                                               3 0.0 a                                                                               3 245.9 a-b                                                                           3 1.567 a-b                                                                           3 0.00 b                                                                             3 0.58 b-c                             5 + 6 3 16.7 a                                                                              3 0.0 a                                                                               3 247.6 a-b                                                                           1 1.513 a-b                                                                           3 0.00 b                                                                             3 0.11 c                               5 + 12                                                                               3 0.0 a                                                                               3 0.0 a                                                                               3 194.6 b-c                                                                           3 1.889 a                                                                             3 0.00 b                                                                             3 0.08 c                               __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 43                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. maxima and E. tenella                                                                                         Lesion Scores                                Treatment                                                                              Mortality                                                                           Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC                                                                             0     2 0.0 a                                                                               2 0.0 b                                                                               2 313.8 a                                                                             2 1.548 c                                                                             2 0.00 c                                                                              2 0.00 d                              IC                                                                             0     3 8.3 a                                                                               3 8.3 b                                                                               3 168.3 d                                                                             2 2.404 a                                                                             3 8.58 a                                                                              3 3.58 a                              A82810                                                                         1     3 8.3 a                                                                               3 8.3 b                                                                               3 188.8 c-d                                                                           2 2.037 b                                                                             3 8.42 a                                                                              3 3.42 a                              3     3 8.3 a                                                                               3 0.0 b                                                                               3 286.9 a                                                                             2 1.588 c                                                                             3 5.78 b                                                                              3 2.25 b-c                            5     3 8.3 a                                                                               3 0.0 b                                                                               3 300.6 a                                                                             2 1.505 c                                                                             3 2.75 c                                                                              3 1.14 d                              Example No. 57                                                                 3     3 33.3 a                                                                              3 33.3 a                                                                              3 191.8 c-d                                                                           1 1.873 b-c                                                                           3 7.50 a-b                                                                            3 3.42 a                              6     3 0.0 a                                                                               3 0.0 b                                                                               3 227.9 b-c                                                                           3 1.828 b-c                                                                           3 5.42 b                                                                              3 3.42 a                              12    3 8.3 a                                                                               3 0.0 b                                                                               3 253.8 a-b                                                                           2 1.740 b-c                                                                           3 0.50 c                                                                              3 1.42 c-d                            A82810 + Example No. 57                                                        1 + 3 3 16.7 a                                                                              3 8.3 b                                                                               3 266.2 a-b                                                                           1 1.701 b-c                                                                           3 3.11 c                                                                              3 3.64 a                              1 + 6 3 0.0 a                                                                               3 0.0 b                                                                               3 255.5 a-b                                                                           3 1.673 c                                                                             3 2.50 c                                                                              3 2.50 a-b                            1 + 12                                                                               3 8.3 a                                                                               3 0.0 b                                                                               3 249.4 a-b                                                                           2 1.776 b-c                                                                           3 0.00 c                                                                              3 1.06 d                              3 + 3 3 0.0 a                                                                               3 0.0 b                                                                               3 286.6 a                                                                             3 1.537 c                                                                             3 0.92 c                                                                              3 1.50 c-d                            3 + 6 3 0.0 a                                                                               3 0.0 b                                                                               3 284.5 a                                                                             3 1.556 c                                                                             3 0.17 c                                                                              3 0.92 d                              3 + 12                                                                               3 8.3 a                                                                               3 0.0 b                                                                               3 263.4 a-b                                                                           2 1.746 b-c                                                                           3 0.08 c                                                                              3 0.17 d                              5 + 3 3 0.0 a                                                                               3 0.0 b                                                                               3 310.1 a                                                                             3 1.517 c                                                                             3 0.00 c                                                                              3 0.67 d                              5 + 6 3 0.0 a                                                                               3 0.0 b                                                                               3 289.3 a                                                                             3 1.571 c                                                                             3 0.00 c                                                                              3 0.25 d                              5 + 12                                                                               3 8.3 a                                                                               3 0.0 b                                                                               3 292.5 a                                                                             2 1.577 c                                                                             3 0.00 c                                                                              3 0.00 d                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 44                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina, E. maxima and E. tenella                                                                        Lesion Scores                                  Treatment                                                                              Mortality                                                                           Mean   Wt. Gain                                                                             Feed/Gain                                                                            Intestinal                                                                           Cecal                                    PPM   # Total %                                                                             # % DTC                                                                               # Mean                                                                               # Mean                                                                               # Mean                                                                               # Mean                                   __________________________________________________________________________     NC                                                                             0     4 0.0 c                                                                               4 0.0 b                                                                               4 220.8 a                                                                            4 1.466 c                                                                            4 0.00 d                                                                             4 0.00 d                                 IC                                                                             0     4 55.0 b                                                                              4 55.0 a                                                                              3  74.2 c   3 3.64 b                                                                             3 3.81 a                                 Example No. 5                                                                  30    4 100.0 a                                                                             4 0.0 b                                                           20    4 95.0 a                                                                              4 5.0 b                                                                               1  89.0 c   1 0.00 d                                                                             1 0.00 d                                 10    4 5.0 c                                                                               4 0.0 b                                                                               4 144.6 b                                                                            3 2.138 a                                                                            4 0.00 d                                                                             4 1.59 c                                 __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 45                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella, E. acervulina and E. maxima                                                                        Lesion Scores                                  Treatment                                                                              Mortality                                                                           Mean   Wt. Gain                                                                             Feed/Gain                                                                            Intestinal                                                                           Cecal                                    PPM   # Total %                                                                             # % DTC                                                                               # Mean                                                                               # Mean                                                                               # Mean                                                                               # Mean                                   __________________________________________________________________________     NC                                                                             0     3 0.0 c                                                                               3  0.0 a                                                                              3 236.7 a                                                                            3 1.551 b                                                                            3 0.00 c                                                                             3 0.00 b                                 IC                                                                             0     3 13.3 c                                                                              3 13.3 a                                                                              3 160.7 b                                                                            1 1.950 a                                                                            3 3.62 a                                                                             3 2.93 a                                 Example No. 5                                                                  10    3 13.3 c                                                                              3 13.3 a                                                                              3 153.7 b                                                                            1 2.176 a                                                                            3 0.25 c                                                                             3 2.30 a                                 7.5   3 13.3 c                                                                              3 13.3 a                                                                              3 164.9 b                                                                            2 2.050 a                                                                            3 0.47 c                                                                             3 1.82 a                                 5     3 26.7 b-c                                                                            3 26.7 a                                                                              3 163.5 b                                                                            1 2.177 a                                                                            3 1.51 b                                                                             3 2.78 a                                 2.5   3 20.0 c                                                                              3 20.0 a                                                                              3 156.3 b   3 1.92 b                                                                             3 2.33 a                                 Example No. 90                                                                 75    3 100.0 a                                                                             3  0.0 a                                                          50    3 46.7 b                                                                              3  0.0 a                                                                              3  70.4 c   3 0.00 c                                                                             3 0.00 b                                 25    3 0.0 c                                                                               3  0.0 a                                                                              3 172.3 b                                                                            3 1.968 a                                                                            3 0.00 c                                                                             3 0.67 b                                 __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 46                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella, E. acervulina and E. maxima                                                                         Lesion Scores                                 Treatment                                                                              Mortality                                                                           Mean   Wt. Gain                                                                             Feed/Gain                                                                             Intestinal                                                                           Cecal                                   PPM   # Total %                                                                             # % DTC                                                                               # Mean                                                                               # Mean # Mean                                                                               # Mean                                  __________________________________________________________________________     NC                                                                             0     3  6.7 a                                                                              3  0.0 a                                                                              3 296.0 a                                                                            2 1.289 c                                                                             3 0.00 b                                                                             3 0.00 d                                IC                                                                             0     3 26.7 a                                                                              3 26.7 a                                                                              3 166.7 b    3 8.11 a                                                                             3 3.83 a                                Example No. 94                                                                 5     2  0.0 a                                                                              2  0.0 a                                                                              2 218.8 b                                                                            2 1.462 b-c                                                                           2 1.60 b                                                                             2 3.20 a                                3.5   2 10.0 a                                                                              2 10.0 a                                                                              2 208.4 b                                                                            1 1.440 c                                                                             2 1.52 b                                                                             2 3.65 a                                2     2 40.0 a                                                                              2 40.0 a                                                                              2 165.1 b    2 7.00 a                                                                             2 3.67 a                                Example No. 98                                                                 5     2  0.0 a                                                                              2  0.0 a                                                                              2 220.3 b                                                                            2 1.478 b-c                                                                           2 0.30 b                                                                             2 2.50 b                                3.5   2 30.0 a                                                                              2 30.0 a                                                                              2 232.4 b                                                                            1 1.614 b-c                                                                           2 1.30 b                                                                             2 3.80 a                                2     2 20.0 a                                                                              2 20.0 a                                                                              2 201.0 b                                                                            1 1.491 b-c                                                                           2 5.67 a                                                                             2 3.47 a                                Example No. 5                                                                  7.5   2  0.0 a                                                                              2  0.0 a                                                                              2 210.4 b                                                                            2 1.557 b-c                                                                           2 0.40 b                                                                             2 2.00 b                                5     2  0.0 a                                                                              2  0.0 a                                                                              2 233.2 b                                                                            2 1.440 c                                                                             2 0.30 b                                                                             2 2.60 b                                2.5   2 10.0 a                                                                              2 10.0 a                                                                              2 184.8 b                                                                            1 1.779 a-b                                                                           2 1.70 b                                                                             2 3.65 a                                __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 47                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                     Lesion Scores                                Treatment                                                                              Mortality                                                                           Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC                                                                             0     3 25.0 a                                                                              3 0.0 a                                                                               3 318.5 a                                                                             1 1.425 c                                                                             3 0.00 d                                                                              3 0.00 c                              IC                                                                             0     3 41.7 a                                                                              3 33.3 a                                                                              3 229.6 c     3 8.17 a-b                                                                            3 3.22 a-b                            A80190                                                                         8     3 16.7 a                                                                              3 0.0 a                                                                               3 240.8 b-c                                                                           2 1.591 b-c                                                                           3 7.50 b                                                                              3 2.83 a-b                            Example No. 5                                                                  2.5   3  8.3 a                                                                              3 8.3 a                                                                               3 213.0 c                                                                             2 1.852 a                                                                             3 9.00 a                                                                              3 3.17 a-b                            5     3  0.0 a                                                                              3 0.0 a                                                                               3 242.5 b-c                                                                           3 1.653 b                                                                             3 0.25 d                                                                              3 3.50 a                              A80190 + Example No. 5                                                         8 + 2.5                                                                              3  0.0 a                                                                              3 0.0 a                                                                               3 274.3 a-c                                                                           3 1.488 c                                                                             3 1.58 c                                                                              3 2.92 a-b                            8 + 5 3  0.0 a                                                                              3 0.0 a                                                                               3 297.8 a-b                                                                           3 1.440 c                                                                             3 0.00 d                                                                              3 1.92 b                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 48                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                     Lesion Scores                                Treatment                                                                              Mortality                                                                           Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                           Cecal                                  PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean                                                                               # Mean                                 __________________________________________________________________________     NC                                                                             0     3 0.0 a                                                                               3 0.0 a                                                                               3 321.8 a                                                                             3 1.391 c                                                                             3 0.00 b                                                                             3 0.00 c                               IC                                                                             0     3 0.0 a                                                                               3 0.0 a                                                                               3 199.5 f                                                                             3 1.852 a                                                                             3 6.08 a                                                                             3 2.92 a-b                             A204                                                                           2     3 0.0 a                                                                               3 0.0 a                                                                               3 252.2 c-e                                                                           3 1.649 a-c                                                                           3 4.00 a                                                                             3 3.42 a                               4     3 0.0 a                                                                               3 0.0 a                                                                               3 247.8 d-e                                                                           3 1.686 a-b                                                                           3 6.50 a                                                                             3 3.08 a-b                             8     3 0.0 a                                                                               3 0.0 a                                                                               3 271.0 c-e                                                                           3 1.489 b-c                                                                           3 0.92 b                                                                             3 3.58 a                               Example No. 5                                                                  2     3 0.0 a                                                                               3 0.0 a                                                                               3 245.8 d-e                                                                           3 1.652 a-c                                                                           3 4.17 a                                                                             3 3.08 a-b                             4     3 0.0 a                                                                               3 0.0 a                                                                               3 243.8 d-e                                                                           3 1.676 a-c                                                                           3 0.25 b                                                                             3 3.17 a-b                             8     3 0.0 a                                                                               3 0.0 a                                                                               3 234.3 d-e                                                                           3 1.671 a-c                                                                           3 0.08 b                                                                             3 2.33 a-b                             A204 + Example No. 5                                                           2 + 2 3 8.3 a                                                                               3 8.3 a                                                                               3 265.2 c-e                                                                           2 1.596 a-c                                                                           3 0.83 b                                                                             3 3.25 a                               2 + 4 3 0.0 a                                                                               3 0.0 a                                                                               3 276.0 c-e                                                                           3 1.491 b-c                                                                           3 0.08 b                                                                             3 3.50 a                               2 + 8 3 0.0 a                                                                               3 0.0 a                                                                               3 246.8 d-e                                                                           3 1.637 a-c                                                                           3 0.00 b                                                                             3 0.67 c                               4 + 2 3 8.3 a                                                                               3 0.0 a                                                                               3 262.4 c-e                                                                           2 1.574 a-c                                                                           3 0.00 b                                                                             3 2.81 a-b                             4 + 4 3 0.0 a                                                                               3 0.0 a                                                                               3 280.7 b-d                                                                           3 1.540 b-c                                                                           3 0.00 b                                                                             3 1.83 b                               4 + 8 3 8.3 a                                                                               3 0.0 a                                                                               3 229.7 e                                                                             2 1.683 a-c                                                                           3 0.00 b                                                                             3 0.53 c                               8 + 2 3 16.7 a                                                                              3 0.0 a                                                                               3 312.7 a-b                                                                           2 1.442 b-c                                                                           3 0.00 b                                                                             3 2.58 a-b                             8 + 4 3 0.0 a                                                                               3 0.0 a                                                                               3 293.3 a-c                                                                           3 1.496 b-c                                                                           3 0.00 b                                                                             3 0.92 c                               8 + 8 3 0.0 a                                                                               3 0.0 a                                                                               3 246.3 d-e                                                                           3 1.659 a-c                                                                           3 0.00 b                                                                             3 0.25 c                               __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 49                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                     Lesion Scores                                Treatment                                                                              Mortality                                                                           Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                           Cecal                                  PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean                                                                               #  Mean                                __________________________________________________________________________     NC                                                                             0     3 8.3 b-c                                                                             3 0.0 a                                                                               3 325.5 a                                                                             2 1.359 c                                                                             3 0.00 c                                                                              3 0.00 c                              IC                                                                             0     3 0.0 c                                                                               3 0.0 a                                                                               3 257.4 c                                                                             3 1.687 b                                                                             3 6.58 a                                                                              3 3.33 a                              A82810                                                                         1     3 0.0 c                                                                               3 0.0 a                                                                               3 262.1 c                                                                             3 1.638 b-c                                                                           3 6.17 a                                                                              3 3.42 a                              3     3 0.0 c                                                                               3 0.0 a                                                                               3 288.0 a-c                                                                           3 1.506 b-c                                                                           3 2.75 b                                                                              3 2.92 a                              5     3 0.0 c                                                                               3 0.0 a                                                                               3 319.8 a-b                                                                           3 1.424 b-c                                                                           3 0.92 b-c                                                                            3 1.75 b                              Example No. 113                                                                6     3 8.3 b-c                                                                             3 0.0 a                                                                               3 255.2 c                                                                             2 1.662 b-c                                                                           3 0.17 b-c                                                                            3 2.06 b                              12    3 41.7 b                                                                              3 0.0 a                                                                               3 179.4 d     3 0.00 c                                                                              3 0.67 c                              24    1 75.0 a                                                                              1 0.0 a                                                                               1 53.8 f      1 0.00 c                                                                              1 0.00 c                              A82810 + Example No. 113                                                       1 + 6 3 0.0 c                                                                               3 0.0 a                                                                               3 264.0 c                                                                             3 1.641 b-c                                                                           3 0.00 c                                                                              3 1.00 c                              1 + 12                                                                               3 25.0 b-c                                                                            3 0.0 a                                                                               3 160.4 d                                                                             1 2.182 a                                                                             3 0.00 c                                                                              3 0.11 c                              3 + 6 3 0.0 c                                                                               3 0.0 a                                                                               3 274.2 b-c                                                                           3 1.580 b-c                                                                           3 0.00 c                                                                              3 0.17 c                              3 + 12                                                                               3 8.3 b-c                                                                             3 0.0 a                                                                               3 184.2 d                                                                             2 2.160 a                                                                             3 0.00 c                                                                              3 0.00 c                              5 + 6 3 0.0 c                                                                               3 0.0 a                                                                               3 265.5 c                                                                             3 1.640 b-c                                                                           3 0.00 c                                                                              3 0.08 c                              5 + 12                                                                               3 33.3 b-c                                                                            3 0.0 a                                                                               3 113.1 e     3 0.00 c                                                                              3 0.00 c                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 50                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                     Lesion Scores                                Treatment                                                                              Mortality                                                                           Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                           Cecal                                  PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean                                                                               # Mean                                 __________________________________________________________________________     NC                                                                             0     3 0.0 a                                                                               3 0.0 a                                                                               3 307.9 a-b                                                                           3 1.516 b-c                                                                           3 0.00 b                                                                             3 0.00 d                               IC                                                                             0     3 0.0 a                                                                               3 0.0 a                                                                               3 258.3 b-e                                                                           3 1.670 a-c                                                                           3 5.00 a                                                                             3 2.92 a-b                             A82810                                                                         1     3 0.0 a                                                                               3 0.0 a                                                                               3 250.0 c-e                                                                           3 1.692 a-c                                                                           3 3.75 a                                                                             3 2.67 a-b                             3     3 0.0 a                                                                               3 0.0 a                                                                               3 285.3 a-d                                                                           3 1.599 a-c                                                                           3 1.33 b                                                                             3 2.50 a-b                             5     3 0.0 a                                                                               3 0.0 a                                                                               3 313.5 a                                                                             3 1.446 c                                                                             3 0.25 b                                                                             3 0.92 c-d                             Example No. 113                                                                2     3 0.0 a                                                                               3 0.0 a                                                                               3 254.3 b-e                                                                           3 1.714 a-c                                                                           3 3.92 a                                                                             3 3.33 a                               4     3 8.3 a                                                                               3 0.0 a                                                                               3 285.4 a-d                                                                           2 1.541 a-c                                                                           3 0.39 b                                                                             3 3.19 a-b                             8     3 0.0 a                                                                               3 0.0 a                                                                               3 239.7 c-e                                                                           3 1.724 a-b                                                                           3 0.00 b                                                                             3 0.42 c-d                             A82810 + Example No. 113                                                       1 + 2 3 0.0 a                                                                               3 0.0 a                                                                               3 289.9 a-d                                                                           3 1.527 a-c                                                                           3 0.42 b                                                                             3 1.83 b-c                             1 + 4 3 0.0 a                                                                               3 0.0 a                                                                               3 278.3 a-e                                                                           3 1.528 a-c                                                                           3 0.00 b                                                                             3 1.08 c-d                             1 + 8 3 0.0 a                                                                               3 0.0 a                                                                               3 236.2 d-e                                                                           3 1.747 a-b                                                                           3 0.00 b                                                                             3 0.33 c-d                             3 + 2 3 0.0 a                                                                               3 0.0 a                                                                               3 316.3 a                                                                             3 1.473 b-c                                                                           3 0.00 b                                                                             3 0.83 c-d                             3 + 4 3 8.3 a                                                                               3 0.0 a                                                                               3 272.9 a-e                                                                           2 1.482 b-c                                                                           3 0.00 b                                                                             3 0.72 c-d                             3 + 8 3 8.3 a                                                                               3 0.0 a                                                                               3 224.6 e                                                                             2 1.821 a                                                                             3 0.00 b                                                                             3 0.00 d                               5 + 2 3 0.0 a                                                                               3 0.0 a                                                                               3 293.7 a-c                                                                           3 1.477 b-c                                                                           3 0.00 b                                                                             3 0.58 c-d                             5 + 4 3 0.0 a                                                                               3 0.0 a                                                                               3 274.4 a-e                                                                           3 1.568 a-c                                                                           3 0.00 b                                                                             3 0.50 c-d                             5 + 8 3 0.0 a                                                                               3 0.0 a                                                                               3 234.9 d-e                                                                           3 1.722 a-b                                                                           3 0.00 b                                                                             3 0.00 d                               __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 51                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. maxima and E. tenella                                                                                        Lesion Scores                                 Treatment                                                                              Mortality                                                                           Mean   Wt. Gain                                                                             Feed/Gain                                                                             Intestinal                                                                            Cecal                                  PPM   # Total %                                                                             # % DTC                                                                               # Mean                                                                               # Mean # Mean # Mean                                 __________________________________________________________________________     NC                                                                             0     3 0.0 b                                                                               3 0.0 b                                                                               3 345.9 a                                                                            3 1.375 c                                                                             3 0.00 d                                                                              3 0.00 e                               IC                                                                             0     3 25.0 a-b                                                                            3 16.7 b                                                                              3 245.9 a    3 7.64 a                                                                              3 3.67 a                               A82810                                                                         1     3 41.7 a                                                                              3 41.7 a                                                                              3 259.3 a    3 8.67 a                                                                              3 3.67 a                               2     3 8.3 b                                                                               3 8.3 b                                                                               3 281.8 a                                                                            2 1.482 b-c                                                                           3 7.00 a                                                                              3 2.58 b-c                             3     3 0.0 b                                                                               3 0.0 b                                                                               3 270.3 a                                                                            3 1.554 b-c                                                                           3 8.25 a                                                                              3 2.42 c                               Example No. 113                                                                2     3 0.0 b                                                                               3 0.0 b                                                                               3 190.8 a                                                                            3 1.956 a                                                                             3 7.75 a                                                                              3 3.33 a-b                             4     3 16.7 b                                                                              3 16.7 b                                                                              3 232.8 a                                                                            2 1.848 a-b                                                                           3 4.08 b                                                                              3 3.67 a                               8     3 0.0 b                                                                               3 0.0 b                                                                               3 234.1 a                                                                            3 1.786 a-b                                                                           3 0.67 d                                                                              3 1.00 d-e                             A82810 + Example No. 113                                                       1 + 2 3 0.0 b                                                                               3 0.0 b                                                                               3 262.0 a                                                                            3 1.674 a-c                                                                           3 3.08 b-c                                                                            3 2.83 a-c                             1 + 4 3 8.3 b                                                                               3 0.0 b                                                                               3 281.6 a                                                                            2 1.569 b-c                                                                           3 2.00 b-d                                                                            3 2.39 c                               1 + 8 3 0.0 b                                                                               3 0.0 b                                                                               3 233.4 a                                                                            3 1.741 a-b                                                                           3 0.33 d                                                                              3 0.83 d-e                             3 + 2 3 0.0 b                                                                               3 0.0 b                                                                               3 313.3 a                                                                            3 1.509 b-c                                                                           3 1.33 c-d                                                                            3 1.08 d                               3 + 4 3 0.0 b                                                                               3 0.0 b                                                                               3 300.0 a                                                                            3 1.538 b-c                                                                           3 0.00 d                                                                              3 0.58 d-e                             3 + 8 3 0.0 b                                                                               3 0.0 b                                                                               3 251.7 a                                                                            3 1.733 a-b                                                                           3 0.00 d                                                                              3 0.08 e                               5 + 2 3 0.0 b                                                                               3 0.0 b                                                                               3 303.4 a                                                                            3 1.478 b-c                                                                           3 0.00 d                                                                              3 0.25 d-e                             5 + 4 3 0.0 b                                                                               3 0.0 b                                                                               3 295.4 a                                                                            3 1.541 b-c                                                                           3 0.00 d                                                                              3 0.17 d-e                             5 + 8 3 0.0 b                                                                               3 0.0 b                                                                               3 279.8 a                                                                            3 1.664 a-c                                                                           3 0.00 d                                                                              3 0.00 e                               __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 52                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                     Lesion Scores                                Treatment                                                                              Mortality                                                                           Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                           Cecal                                  PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean                                                                               # Mean                                 __________________________________________________________________________     NC                                                                             0     3 0.0 a                                                                               3 0.0 a                                                                               3 330.2 a                                                                             3 1.346 d                                                                             3 0.00 c                                                                             3 0.00 c                               IC                                                                             0     3 0.0 a                                                                               3 0.0 a                                                                               3 240.8 c-d                                                                           3 1.682 b-d                                                                           3 7.92 a                                                                             3 3.58 a                               A204                                                                           2     3 8.3 a                                                                               3 8.3 a                                                                               3 247.4 c-d                                                                           2 1.695 b-d                                                                           3 7.17 a                                                                             3 3.33 a-b                             4     3 0.0 a                                                                               3 0.0 a                                                                               3 248.1 c-d                                                                           3 1.707 b-d                                                                           3 4.58 b                                                                             3 2.83 a-b                             8     3 0.0 a                                                                               3 0.0 a                                                                               3 289.4 a-c                                                                           3 1.530 c-d                                                                           3 0.92 c                                                                             3 3.17 a-b                             Example No. 113                                                                2     3 0.0 a                                                                               3 0.0 a                                                                               3 228.5 d                                                                             3 1.800 b-c                                                                           3 5.00 b                                                                             3 3.33 a-b                             4     3 0.0 a                                                                               3 0.0 a                                                                               3 260.6 b-d                                                                           3 1.747 b-c                                                                           3 0.00 c                                                                             3 2.17 b                               8     3 8.3 a                                                                               3 0.0 a                                                                               3 165.9 e                                                                             2 2.232 a                                                                             3 0.00 c                                                                             3 0.67 c                               A204 + Example No. 113                                                         2 + 2 3 0.0 a                                                                               3 0.0 a                                                                               3 285.7 a-c                                                                           3 1.557 c-d                                                                           3 0.25 c                                                                             3 2.92 a-b                             2 + 4 3 0.0 a                                                                               3 0.0 a                                                                               3 281.1 b-d                                                                           3 1.634 b-d                                                                           3 0.00 c                                                                             3 0.75 c                               2 + 8 3 16.7 a                                                                              3 0.0 a                                                                               3 190.0 e                                                                             2 2.060 a-b                                                                           3 0.00 c                                                                             3 0.50 c                               4 + 2 3 8.3 a                                                                               3 0.0 a                                                                               3 270.2 b-d                                                                           2 1.604 b-d                                                                           3 0.00 c                                                                             3 2.08 b                               4 + 4 3 0.0 a                                                                               3 0.0 a                                                                               3 258.9 b-d                                                                           3 1.669 b-d                                                                           3 0.00 c                                                                             3 0.75 c                               4 + 8 3 16.7 a                                                                              3 0.0 a                                                                               3 185.4 e                                                                             2 2.164 a                                                                             3 0.00 c                                                                             3 0.00 c                               8 + 2 3 8.3 a                                                                               3 0.0 a                                                                               3 306.2 a-b                                                                           2 1.546 c-d                                                                           3 0.00 c                                                                             3 0.67 c                               8 + 4 3 0.0 a                                                                               3 0.0 a                                                                               3 272.4 b-d                                                                           3 1.672 b-d                                                                           3 0.00 c                                                                             3 0.33 c                               8 + 8 3 16.7 a                                                                              3 0.0 a                                                                               3 177.0 e                                                                             1 2.424 a                                                                             3 0.00 c                                                                             3 0.00 c                               __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 53                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina, E. maxima and E. tenella                                                                          Lesion Scores                                Treatment                                                                              Mortality                                                                           Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                           Cecal                                  PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC                                                                             0     4 0.0 a                                                                               4 0.0 a                                                                               4 325.9 a                                                                             4 1.423 c-d                                                                           4 0.00 c                                                                              4 0.00 f                              IC                                                                             0     4 0.0 a                                                                               4 0.0 a                                                                               4 254.8 c-e                                                                           4 1.666 a-c                                                                           4 8.81 a                                                                              4 3.31 c                              A80190                                                                         30    4 0.0 a                                                                               4 0.0 a                                                                               4 313.5 a-b                                                                           4 1.428 c-d                                                                           4 0.00 c                                                                              4 0.44 e                              40    4 0.0 a                                                                               4 0.0 a                                                                               4 317.3 a                                                                             4 1.392 d                                                                             4 0.00 c                                                                              4 0.00 f                              50    4 0.0 a                                                                               4 0.0 a                                                                               4 309.2 a-b                                                                           4 1.462 c-d                                                                           4 0.00 c                                                                              4 0.00 f                              Example No. 57                                                                 2     4 0.0 a                                                                               4 0.0 a                                                                               4 221.9 e                                                                             4 1.809 a                                                                             4 8.50 b                                                                              4 3.56 b                              3     4 0.0 a                                                                               4 0.0 a                                                                               4 232.4 d-e                                                                           4 1.730 a-b                                                                           4 8.69 a-b                                                                            4 3.06 d                              4     4 0.0 a                                                                               4 0.0 a                                                                               4 222.9 e                                                                             4 1.880 a                                                                             4 8.88 a                                                                              4 3.81 a                              A80190 + Example No. 57                                                        30 + 2                                                                               4 6.3 a                                                                               4 0.0 a                                                                               4 307.5 a-b                                                                           4 1.520 b-d                                                                           4 0.00 c                                                                              4 0.00 f                              30 + 3                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 292.4 a-c                                                                           4 1.533 b-d                                                                           4 0.00 c                                                                              4 0.00 f                              30 + 4                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 306.8 a-b                                                                           4 1.472 c-d                                                                           4 0.00 c                                                                              4 0.00 f                              40 + 2                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 285.4 a-c                                                                           4 1.468 c-d                                                                           4 0.00 c                                                                              4 0.00 f                              40 + 3                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 298.0 a-c                                                                           4 1.498 b-d                                                                           4 0.00 c                                                                              4 0.00 f                              40 + 4                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 287.3 a-c                                                                           4 1.538 b-d                                                                           4 0.00 c                                                                              4 0.00 f                              50 + 2                                                                               4 6.3 a                                                                               4 0.0 a                                                                               4 299.4 a-c                                                                           4 1.524 b-d                                                                           4 0.00 c                                                                              4 0.00 f                              50 + 3                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 255.1 c-e                                                                           4 1.781 a                                                                             4 0.00 c                                                                              4 0.00 f                              50 + 4                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 267.0 b-d                                                                           4 1.672 a-c                                                                           4 0.00 c                                                                              4 0.00 f                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 54                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina, E. maxima and E. tenella                                                                          Lesion Scores                                Treatment                                                                              Mortality                                                                           Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC                                                                             0     4 0.0 a                                                                               4 0.0 a                                                                               4 322.3 a                                                                             4 1.356 e                                                                             4 0.00 e                                                                              4 0.38 d                              IC                                                                             0     4 18.8 a                                                                              4 18.8 a                                                                              4 203.6 c                                                                             4 1.865 b-d                                                                           4 8.44 a                                                                              4 3.44 a                              A80190                                                                         30    4 6.3 a                                                                               4 0.0 a                                                                               4 259.4 b                                                                             4 1.624 c-e                                                                           4 6.90 a-b                                                                            4 3.54 a                              40    4 0.0 a                                                                               4 0.0 a                                                                               4 229.6 b-c                                                                           4 1.670 b-e                                                                           4 5.13 b-c                                                                            4 2.81 a-b                            50    4 0.0 a                                                                               4 0.0 a                                                                               4 285.5 a-b                                                                           4 1.449 e                                                                             4 1.94 d-e                                                                            4 2.00 b-c                            Example No. 57                                                                 2     4 6.3 a                                                                               4 6.3 a                                                                               4 186.4 c-d                                                                           4 1.955 b                                                                             4 8.81 a                                                                              4 3.56 a                              3     4 12.5 a                                                                              4 12.5 a                                                                              4 203.0 c                                                                             4 1.885 b-c                                                                           4 8.31 a                                                                              4 3.75 a                              4     4 6.3 a                                                                               4 6.3 a                                                                               4 151.9 d                                                                             4 2.285 a                                                                             4 8.81 a                                                                              4 3.88 a                              A80190 + Example No. 57                                                        30 + 2                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 260.5 b                                                                             4 1.589 c-e                                                                           4 3.75 c-d                                                                            4 3.56 a                              30 + 3                                                                               4 6.3 a                                                                               4 0.0 a                                                                               4 270.8 a-b                                                                           4 1.490 d-e                                                                           4 3.08 c-e                                                                            4 3.19 a-b                            30 + 4                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 274.6 a-b                                                                           4 1.495 d-e                                                                           4 0.81 e                                                                              4 2.00 b-c                            40 + 2                                                                               4 6.3 a                                                                               4 6.3 a                                                                               4 256.9 b                                                                             4 1.549 c-e                                                                           4 3.81 c-d                                                                            4 2.75 a-b                            40 + 3                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 290.2 a-b                                                                           4 1.486 d-e                                                                           4 0.94 e                                                                              4 1.50 c-d                            40 + 4                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 276.8 a-b                                                                           4 1.554 c-e                                                                           4 0.31 e                                                                              4 1.44 c-d                            50 + 2                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 287.8 a-b                                                                           4 1.486 d-e                                                                           4 0.13 e                                                                              4 1.31 c-d                            50 + 3                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 271.2 a-b                                                                           4 1.615 c-e                                                                           4 0.13 e                                                                              4 0.88 c-d                            50 + 4                                                                               4 0.0 a                                                                               4 0.0 a                                                                               4 263.4 b                                                                             4 1.566 c-e                                                                           4 0.50 e                                                                              4 0.63 d                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 55                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella, E. acervulina and E. Maxima                                                                          Lesion Scores                                Treatment                                                                              Mortality                                                                           Mean   Wt. Gain                                                                              Feed/Gain                                                                             Intestinal                                                                            Cecal                                 PPM   # Total %                                                                             # % DTC                                                                               # Mean # Mean # Mean # Mean                                __________________________________________________________________________     NC                                                                             0     3 0.0 b                                                                               3 0.0 b                                                                               3 218.8 a                                                                             3 1.285 d                                                                             3 0.00 b                                                                              3 0.00 d                              IC                                                                             0     3 40.0 a-b                                                                            3 40.0 a                                                                              3 105.2 c     3 1.50 a                                                                              3 3.44 a                              Example No. 22                                                                 15    3 86.7 a                                                                              3 0.0 b                                                                               1 5.9 e       1 0.00 b                                                                              1 0.00 d                              10    3 53.3 a-b                                                                            3 0.0 b                                                                               2 84.4 c-d                                                                            1 2.352 a                                                                             2 0.00 b                                                                              2 0.00 d                              5     3 13.3 b                                                                              3 0.0 b                                                                               3 144.6 b                                                                             1 1.675 b-c                                                                           3 0.08 b                                                                              3 2.05 b                              Example No. 15                                                                 15    3 6.7 b                                                                               3 0.0 b                                                                               3 146.4 b                                                                             2 1.811 b                                                                             3 0.00 b                                                                              3 1.77 b-c                            10    3 0.0 b                                                                               3 0.0 b                                                                               3 160.1 b                                                                             3 1.588 c                                                                             3 0.00 b                                                                              3 3.27 a                              5     3 26.7 b                                                                              3 26.7 a-b                                                                            3 132.3 b                                                                             1 1.747 b                                                                             3 0.00 b                                                                              3 3.60 a                              __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 56                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                         Lesion Scores                            Treatment                                                                            Mortality Mean  Wt. Gain                                                                               Feed/Gain                                                                              Intestinal                                                                             Cecal                            PPM   # Total %                                                                              # % DTC # Mean  # Mean  # Mean  # Mean                           __________________________________________________________________________     NC                                                                             0     3 8.3                                                                               b  3 0.0                                                                               a  3 323.0                                                                             a  2 1.396                                                                             d  3 0.00                                                                              c  3 0.22                                                                              c                           IC                                                                             0     3 16.7                                                                              b  3 16.7                                                                              a  3 195.7                                                                             e  2 2.032                                                                             a  3 7.67                                                                              a  3 3.75                                                                              a                           A82810                                                                         1     3 8.3                                                                               b  3 8.3                                                                               a  3 202.0                                                                             e  2 2.032                                                                             a  3 7.42                                                                              a  3 3.50                                                                              a                           3     3 0.0                                                                               b  3 0.0                                                                               a  3 278.3                                                                             a-d                                                                               3 1.565                                                                             b-d                                                                               3 2.33                                                                              b  3 3.00                                                                              a                           5     3 0.0                                                                               b  3 0.0                                                                               a  3 317.3                                                                             a  3 1.448                                                                             c-d                                                                               3 0.50                                                                              c  3 1.50                                                                              b                           Example No. 36                                                                 6     3 33.3                                                                              a  3 25.0                                                                              a  3 211.6                                                                             e          3 7.08                                                                              a  3 3.69                                                                              a                           12    3 0.0                                                                               b  3 0.0                                                                               a  3 256.2                                                                             c-d                                                                               3 1.701                                                                             b  3 0.58                                                                              c  3 3.58                                                                              a                           24    3 0.0                                                                               b  3 0.0                                                                               a  3 232.1                                                                             d-e                                                                               3 1.832                                                                             a  3 0.00                                                                              c  3 1.42                                                                              b                           A82810 + Example No. 36                                                        1 + 6 3 0.0                                                                               b  3 0.0                                                                               a  3 268.7                                                                             b-d                                                                               3 1.533                                                                             b-d                                                                               3 0.17                                                                              c  3 2.92                                                                              a                           1 + 12                                                                               3 0.0                                                                               b  3 0.0                                                                               a  3 270.8                                                                             b-d                                                                               3 1.609                                                                             b-d                                                                               3 0.00                                                                              c  3 0.75                                                                              b-c                         1 + 24                                                                               3 0.0                                                                               b  3 0.0                                                                               a  3 212.1                                                                             e  3 1.902                                                                             a  3 0.00                                                                              c  3 1.08                                                                              b-c                         3 + 6 3 0.0                                                                               b  3 0.0                                                                               a  3 311.0                                                                             a-b                                                                               3 1.478                                                                             c-d                                                                               3 0.00                                                                              c  3 0.92                                                                              b-c                         3 + 12                                                                               3 0.0                                                                               b  3 0.0                                                                               a  3 278.8                                                                             a-d                                                                               3 1.581                                                                             b-d                                                                               3 0.00                                                                              c  3 0.17                                                                              c                           3 + 24                                                                               3 0.0                                                                               b  3 0.0                                                                               a  3 214.1                                                                             e  3 1.954                                                                             a  3 0.00                                                                              c  3 0.17                                                                              c                           5 + 6 3 0.0                                                                               b  3 0.0                                                                               a  3 290.9                                                                             a-c                                                                               3 1.501                                                                             c-d                                                                               3 0.00                                                                              c  3 0.17                                                                              c                           5 + 12                                                                               3 0.0                                                                               b  3 0.0                                                                               a  3 269.5                                                                             b-d                                                                               3 1.620                                                                             b-c                                                                               3 0.00                                                                              c  3 0.25                                                                              c                           5 + 24                                                                               3 8.3                                                                               b  3 0.0                                                                               a  3 205.8                                                                             e  2 1.974                                                                             a  3 0.00                                                                              c  3 0.19                                                                              c                           __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 57                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina, E. maxima and E. tenella                                                                              Lesion Scores                            Treatment                                                                            Mortality Mean  Wt. Gain                                                                               Feed/Gain                                                                              Intestinal                                                                             Cecal                            PPM   # Total %                                                                              # % DTC # Mean  # Mean  # Mean  # Mean                           __________________________________________________________________________     NC                                                                             0     4 0.0                                                                               d  4 0.0                                                                               a  4 224.4                                                                             a  4 1.655                                                                             f  4 0.00                                                                              b  4 0.00                                                                              f                           IC                                                                             0     4 15.0                                                                              d  4 5.0                                                                               a  4 117.2                                                                             d-f                                                                               1 2.602                                                                             c  4 6.43                                                                              a  4 3.17                                                                              a-b                         Example No. 94                                                                 20    4 95.0                                                                              a  4 0.0                                                                               a  1 108.4                                                                             d-f        1 0.00                                                                              b  1 0.00                                                                              f                           15    4 20.0                                                                              c-d                                                                               4 0.0                                                                               a  4 106.0                                                                             e-f                                                                               1 3.461                                                                             a  4 0.00                                                                              b  4 0.31                                                                              e-f                         12.5  4 0.0                                                                               d  4 0.0                                                                               a  4 127.4                                                                             d-f                                                                               4 2.543                                                                             c  4 0.00                                                                              b  4 0.25                                                                              e-f                         10    4 10.0                                                                              d  4 0.0                                                                               a  4 147.8                                                                             c-f                                                                               3 2.023                                                                             e  4 0.00                                                                              b  4 1.63                                                                              c-e                         5     4 5.0                                                                               d  4 5.0                                                                               a  4 199.2                                                                             a-b                                                                               3 1.917                                                                             e  4 0.00                                                                              b  4 2.16                                                                              c-d                         Example No. 98                                                                 20    4 90.0                                                                              a  4 0.0                                                                               a  2 14.9                                                                              g          2 0.00                                                                              b  2 1.00                                                                              d-f                         15    4 55.0                                                                              b  4 0.0                                                                               a  4 94.6                                                                              f          4 0.00                                                                              b  4 0.38                                                                              e-f                         12.5  4 35.0                                                                              c  4 0.0                                                                               a  4 101.9                                                                             e-f        4 0.00                                                                              b  4 0.90                                                                              d-f                         10    4 0.0                                                                               d  4 0.0                                                                               a  4 142.4                                                                             c-f                                                                               4 2.260                                                                             d  4 0.00                                                                              b  4 1.30                                                                              d-f                         5     4 0.0                                                                               d  4 0.0                                                                               a  4 183.1                                                                             b-c                                                                               4 1.854                                                                             e  4 0.00                                                                              b  4 2.35                                                                              b-c                         NC (Equal volume of ACETONE added)                                             0     2 0.0                                                                               d  2 0.0                                                                               a  2 235.5                                                                             a  2 1.521                                                                             f  2 0.00                                                                              b  2 0.00                                                                              f                           IC (Equal volume of ACETONE added)                                             0     2 10.0                                                                              d  2 10.0                                                                              a  2 101.1                                                                             e-f                                                                               1 2.931                                                                             b  2 6.25                                                                              a  2 3.80                                                                              a                           Example No. 94 (Dissolved in ACETONE)                                          20    2 100.0                                                                             a  2 0.0                                                                               a                                                           15    2 40.0                                                                              b-c                                                                               2 0.0                                                                               a  2 94.4                                                                              f          2 0.00                                                                              b  2 0.50                                                                              e-f                         10    2 0.0                                                                               d  2 0.0                                                                               a  2 166.5                                                                             b-e                                                                               2 2.003                                                                             e  2 0.00                                                                              b  2 1.30                                                                              d-f                         5     2 0.0                                                                               d  2 0.0                                                                               a  2 169.5                                                                             b-d                                                                               2 1.986                                                                             e  2 0.60                                                                              b  2 2.20                                                                              b-d                         __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 58                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina, and E. tenella                                                                                        Lesion Scores                            Treatment                                                                            Mortality Mean  Wt. Gain                                                                               Feed/Gain                                                                              Intestinal                                                                             Cecal                            PPM   # Total %                                                                              # % DTC # Mean  # Mean  # Mean  # Mean                           __________________________________________________________________________     NC                                                                             0     3 0.0                                                                               a  3 0.0                                                                               a  3 322.8                                                                             a  3 1.448                                                                             c  3 0.00                                                                              b  3 0.00                                                                              e                           IC                                                                             0     3 0.0                                                                               a  3 0.0                                                                               a  3 256.0                                                                             b-c                                                                               3 1.691                                                                             a-c                                                                               3 7.42                                                                              a  3 2.92                                                                              a                           A204                                                                           2     3 8.3                                                                               a  3 0.0                                                                               a  3 263.9                                                                             b-c                                                                               2 1.744                                                                             a-b                                                                               3 8.00                                                                              a  3 3.25                                                                              a                           4     3 0.0                                                                               a  3 0.0                                                                               a  3 259.7                                                                             b-c                                                                               3 1.595                                                                             a-c                                                                               3 6.00                                                                              a  3 3.08                                                                              a                           8     3 8.3                                                                               a  3 0.0                                                                               a  3 271.8                                                                             b-c                                                                               2 1.537                                                                             a-c                                                                               3 1.69                                                                              b  3 2.78                                                                              a                           Example No. 108                                                                2     3 0.0                                                                               a  3 0.0                                                                               a  3 237.3                                                                             c  3 1.831                                                                             a  3 7.75                                                                              a  3 3.17                                                                              a                           4     3 8.3                                                                               a  3 0.0                                                                               a  3 237.1                                                                             c  2 1.840                                                                             a  3 1.81                                                                              b  3 3.03                                                                              a                           8     3 8.3                                                                               a  3 0.0                                                                               a  3 242.9                                                                             c  2 1.707                                                                             a-c                                                                               3 0.00                                                                              b  3 2.22                                                                              a-c                         A204 + Example No. 108                                                         2 + 2 3 0.0                                                                               a  3 0.0                                                                               a  3 271.4                                                                             b-c                                                                               3 1.579                                                                             a-c                                                                               3 0.92                                                                              b  3 3.08                                                                              a                           2 + 4 3 0.0                                                                               a  3 0.0                                                                               a  3 282.9                                                                             a-c                                                                               3 1.592                                                                             a-c                                                                               3 0.00                                                                              b  3 2.58                                                                              a-b                         2 + 8 3 0.0                                                                               a  3 0.0                                                                               a  3 264.3                                                                             b-c                                                                               3 1.644                                                                             a-c                                                                               3 0.00                                                                              b  3 1.17                                                                              c-e                         4 + 2 3 0.0                                                                               a  3 0.0                                                                               a  3 305.7                                                                             a-b                                                                               3 1.509                                                                             b-c                                                                               3 0.00                                                                              b  3 2.42                                                                              a-b                         4 + 4 3 8.3                                                                               a  3 0.0                                                                               a  3 271.3                                                                             b-c                                                                               2 1.637                                                                             a-c                                                                               3 0.00                                                                              b  3 1.44                                                                              b-d                         4 + 8 3 0.0                                                                               a  3 0.0                                                                               a  3 251.8                                                                             b-c                                                                               3 1.670                                                                             a-c                                                                               3 0.00                                                                              b  3 0.33                                                                              d-e                         8 + 2 3 0.0                                                                               a  3 0.0                                                                               a  3 290.0                                                                             a-c                                                                               3 1.448                                                                             c  3 0.00                                                                              b  3 1.83                                                                              a-c                         8 + 4 3 0.0                                                                               a  3 0.0                                                                               a  3 269.0                                                                             b-c                                                                               3 1.508                                                                             b-c                                                                               3 0.00                                                                              b  3 0.50                                                                              d-e                         8 + 8 3 8.3                                                                               a  3 0.0                                                                               a  3 251.2                                                                             b-c                                                                               2 1.708                                                                             a-c                                                                               3 0.00                                                                              b  3 0.00                                                                              e                           __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 59                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. acervulina                                                                                         Lesion Scores                            Treatment                                                                            Mortality Mean  Wt. Gain                                                                               Feed/Gain                                                                              Intestinal                                                                             Cecal                            PPM   # Total %                                                                              # % DTC # Mean  # Mean  # Mean  # Mean                           __________________________________________________________________________     NC                                                                             0     4 0.0                                                                               e  4 0.0                                                                               e  4 315.6                                                                             a  4 1.457                                                                             c-d                                                                               4 0.00                                                                              g  4 0.00                                                                              d                           IC                                                                             0     4 0.0                                                                               e  4 0.0                                                                               e  4 242.1                                                                             b-d                                                                               4 1.736                                                                             a-d                                                                               4 5.50                                                                              a-b                                                                               4 3.63                                                                              a                           MADURAMICIN                                                                    2     4 6.3                                                                               a-d                                                                               4 0.0                                                                               e  4 267.2                                                                             a-c                                                                               4 1.601                                                                             c-d                                                                               4 5.00                                                                              a-c                                                                               4 3.48                                                                              a                           3     4 0.0                                                                               e  4 0.0                                                                               e  4 265.0                                                                             a-c                                                                               4 1.639                                                                             b-d                                                                               4 4.06                                                                              b-d                                                                               4 3.50                                                                              a                           4     4 0.0                                                                               e  4 0.0                                                                               e  4 298.7                                                                             a  4 1.464                                                                             c-d                                                                               4 4.31                                                                              a-d                                                                               4 3.63                                                                              a                           5     4 0.0                                                                               e  4 0.0                                                                               e  4 291.7                                                                             a-b                                                                               4 1.544                                                                             c-d                                                                               4 4.19                                                                              a-d                                                                               4 3.56                                                                              a                           Example No. 57                                                                 2     4 6.3                                                                               a-d                                                                               4 6.3                                                                               b  4 209.0                                                                             d  4 1.893                                                                             a  4 6.19                                                                              a  4 3.81                                                                              a                           3     4 0.0                                                                               e  4 0.0                                                                               e  4 229.2                                                                             c-d                                                                               4 1.763                                                                             a-c                                                                               4 5.75                                                                              a-b                                                                               4 3.38                                                                              a                           4     4 12.5                                                                              a  4 12.5                                                                              a  4 217.1                                                                             d  4 1.848                                                                             a-b                                                                               4 6.00                                                                              a-b                                                                               4 3.63                                                                              a                           5     4 0.0                                                                               e  4 0.0                                                                               e  4 233.1                                                                             c-d                                                                               4 1.869                                                                             a-b                                                                               4 4.31                                                                              a-d                                                                               4 3.69                                                                              a                           MADURAMICIN + Example No. 57                                                   2 + 2 4 0.0                                                                               e  4 0.0                                                                               e  4 281.3                                                                             a-b                                                                               4 1.544                                                                             c-d                                                                               4 3.31                                                                              c-e                                                                               4 3.56                                                                              a                           2 + 3 4 0.0                                                                               e  4 0.0                                                                               e  4 290.3                                                                             a-b                                                                               4 1.483                                                                             c-d                                                                               4 2.50                                                                              d-f                                                                               4 3.81                                                                              a                           2 + 4 4 0.0                                                                               e  4 0.0                                                                               e  4 289.4                                                                             a-b                                                                               4 1.483                                                                             c-d                                                                               4 1.63                                                                              e-g                                                                               4 3.56                                                                              a                           2 + 5 4 6.3                                                                               a-d                                                                               4 0.0                                                                               e  4 282.5                                                                             a-b                                                                               4 1.567                                                                             c-d                                                                               4 0.77                                                                              f-g                                                                               4 2.48                                                                              a-b                         3 + 2 4 0.0                                                                               e  4 0.0                                                                               e  4 291.6                                                                             a-b                                                                               4 1.591                                                                             c-d                                                                               4 2.56                                                                              d-f                                                                               4 3.50                                                                              a                           3 + 3 4 0.0                                                                               e  4 0.0                                                                               e  4 283.2                                                                             a-b                                                                               4 1.495                                                                             c-d                                                                               4 1.75                                                                              e-g                                                                               4 3.50                                                                              a                           3 + 4 4 0.0                                                                               e  4 0.0                                                                               e  4 296.4                                                                             a  4 1.506                                                                             c-d                                                                               4 1.81                                                                              e-g                                                                               4 2.44                                                                              a-b                         3 + 5 4 0.0                                                                               e  4 0.0                                                                               e  4 278.4                                                                             a-b                                                                               4 1.544                                                                             c-d                                                                               4 1.38                                                                              e-g                                                                               4 2.19                                                                              b                           4 + 2 4 0.0                                                                               e  4 0.0                                                                               e  4 302.2                                                                             a  4 1.448                                                                             d  4 1.50                                                                              e-g                                                                               4 3.31                                                                              a                           4 + 3 4 0.0                                                                               e  4 0.0                                                                               e  4 289.5                                                                             a-b                                                                               4 1.538                                                                             c-d                                                                               4 2.13                                                                              e-g                                                                               4 3.50                                                                              a                           4 + 4 4 0.0                                                                               e  4 0.0                                                                               e  4 283.9                                                                             a-b                                                                               4 1.573                                                                             c-d                                                                               4 0.44                                                                              f-g                                                                               4 2.06                                                                              b                           4 + 5 4 0.0                                                                               e  4 0.0                                                                               e  4 295.0                                                                             a  4 1.509                                                                             c-d                                                                               4 0.69                                                                              f-g                                                                               4 1.44                                                                              b-c                         5 + 2 4 0.0                                                                               e  4 0.0                                                                               e  4 276.4                                                                             a-b                                                                               4 1.537                                                                             c-d                                                                               4 1.81                                                                              e-g                                                                               4 2.50                                                                              a-b                         5 + 3 4 0.0                                                                               e  4 0.0                                                                               e  4 299.0                                                                             a  4 1.476                                                                             c-d                                                                               4 0.94                                                                              f-g                                                                               4 2.50                                                                              a-b                         5 + 4 4 0.0                                                                               e  4 0.0                                                                               e  4 293.2                                                                             a-b                                                                               4 1.484                                                                             c-d                                                                               4 0.50                                                                              f-g                                                                               4 1.38                                                                              b-c                         5 + 5 4 0.0                                                                               e  4 0.0                                                                               e  4 287.4                                                                             a-b                                                                               4 1.575                                                                             c-d                                                                               4 0.19                                                                              g  4 1.00                                                                              c                           __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 60                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. tenella and E. maxima                                                                                             Lesion Scores                            Treatment                                                                            Mortality Mean  Wt. Gain                                                                               Feed/Gain                                                                              Intestinal                                                                             Cecal                            PPM   # Total %                                                                              # % DTC # Mean  # Mean  # Mean  # Mean                           __________________________________________________________________________     NC                                                                             0     4 0.0                                                                               e  4 0.0                                                                               e  4 325.8                                                                             a  4 1.453                                                                             f  4 0.00                                                                              j  4 0.00                                                                              h                           IC                                                                             0     4 25.0                                                                              a-c                                                                               4 18.8                                                                              b-c                                                                               4 154.5                                                                             g  4 2.431                                                                             a  4 8.42                                                                              a  4 3.83                                                                              a                           MADURAMICIN                                                                    2     4 12.5                                                                              b-e                                                                               4 12.5                                                                              b-e                                                                               4 187.8                                                                             f-g                                                                               4 2.155                                                                             b-c                                                                               4 8.06                                                                              a-b                                                                               4 3.69                                                                              a-b                         3     4 12.5                                                                              b-e                                                                               4 12.5                                                                              b-e                                                                               4 218.7                                                                             e-f                                                                               4 1.892                                                                             c-e                                                                               4 7.44                                                                              a-b                                                                               4 3.75                                                                              a-b                         4     4 0.0                                                                               e  4 0.0                                                                               e  4 223.2                                                                             e-f                                                                               4 1.799                                                                             d-f                                                                               4 7.38                                                                              a-b                                                                               4 3.63                                                                              a-c                         5     4 6.3                                                                               b-e                                                                               4 0.0                                                                               e  4 262.1                                                                             c-d                                                                               4 1.600                                                                             e-f                                                                               4 6.44                                                                              a-c                                                                               4 3.88                                                                              a                           Example No. 57                                                                 2     4 25.0                                                                              a-c                                                                               4 25.0                                                                              a-b                                                                               4 163.5                                                                             g  4 2.303                                                                             a-b                                                                               4 8.31                                                                              a-b                                                                               4 3.88                                                                              a                           3     4 37.5                                                                              a  4 37.5                                                                              a  4 159.4                                                                             g  4 2.496                                                                             a  4 8.44                                                                              a  4 3.94                                                                              a                           4     4 6.3                                                                               b-e                                                                               4 6.3                                                                               b-e                                                                               4 185.9                                                                             f-g                                                                               4 2.091                                                                             b-d                                                                               4 7.31                                                                              a-b                                                                               4 3.88                                                                              a                           5     4 6.3                                                                               b-e                                                                               4 6.3                                                                               b-e                                                                               4 203.8                                                                             f  4 2.007                                                                             c-d                                                                               4 7.88                                                                              a-b                                                                               4 3.50                                                                              a-c                         MADURAMICIN + Example No. 57                                                   2 + 2 4 12.5                                                                              b-e                                                                               4 12.5                                                                              b-e                                                                               4 248.7                                                                             d-e                                                                               4 1.787                                                                             d-f                                                                               4 6.63                                                                              a-c                                                                               4 4.00                                                                              a                           2 + 3 4 0.0                                                                               e  4 0.0                                                                               e  4 297.8                                                                             a-c                                                                               4 1.443                                                                             f  4 5.81                                                                              b-d                                                                               4 3.31                                                                              a-c                         2 + 4 4 0.0                                                                               e  4 0.0                                                                               e  4 295.5                                                                             a-d                                                                               4 1.502                                                                             f  4 4.81                                                                              c-e                                                                               4 3.63                                                                              a-c                         2 + 5 4 0.0                                                                               e  4 0.0                                                                               e  4 277.6                                                                             a-d                                                                               4 1.587                                                                             e-f                                                                               4 3.00                                                                              e-h                                                                               4 2.44                                                                              c-e                         3 + 2 4 0.0                                                                               e  4 0.0                                                                               e  4 273.4                                                                             b-d                                                                               4 1.653                                                                             e-f                                                                               4 6.38                                                                              a-c                                                                               4 3.56                                                                              a-c                         3 + 3 4 0.0                                                                               e  4 0.0                                                                               e  4 290.9                                                                             a-d                                                                               4 1.580                                                                             e-f                                                                               4 4.25                                                                              c-g                                                                               4 3.75                                                                              a-b                         3 + 4 4 0.0                                                                               e  4 0.0                                                                               e  4 302.0                                                                             a-c                                                                               4 1.484                                                                             f  4 3.69                                                                              d-g                                                                               4 2.50                                                                              b-e                         3 + 5 4 6.3                                                                               b-e                                                                               4 0.0                                                                               e  4 285.0                                                                             a-d                                                                               4 1.564                                                                             e-f                                                                               4 2.06                                                                              g-j                                                                               4 2.17                                                                              d-f                         4 + 2 4 0.0                                                                               e  4 0.0                                                                               e  4 291.4                                                                             a-d                                                                               4 1.514                                                                             f  4 4.44                                                                              c-g                                                                               4 3.63                                                                              a-c                         4 + 3 4 0.0                                                                               e  4 0.0                                                                               e  4 305.7                                                                             a-c                                                                               4 1.462                                                                             f  4 3.69                                                                              d-g                                                                               4 3.06                                                                              a-d                         4 + 4 4 0.0                                                                               e  4 0.0                                                                               e  4 301.6                                                                             a-c                                                                               4 1.471                                                                             f  4 2.25                                                                              f-j                                                                               4 1.75                                                                              e-f                         4 + 5 4 6.3                                                                               b-e                                                                               4 0.0                                                                               e  4 299.1                                                                             a-c                                                                               4 1.510                                                                             f  4 0.90                                                                              h-j                                                                               4 1.19                                                                              f-g                         5 + 2 4 6.3                                                                               b-e                                                                               4 0.0                                                                               e  4 313.7                                                                             a-c                                                                               4 1.463                                                                             f  4 4.60                                                                              c-f                                                                               4 2.52                                                                              b-e                         5 + 3 4 0.0                                                                               e  4 0.0                                                                               e  4 315.5                                                                             a-b                                                                               4 1.448                                                                             f  4 2.56                                                                              e-i                                                                               4 1.69                                                                              e-f                         5 + 4 4 0.0                                                                               e  4 0.0                                                                               e  4 302.4                                                                             a-c                                                                               4 1.461                                                                             f  4 1.00                                                                              h-j                                                                               4 1.19                                                                              f-g                         5 + 5 4 0.0                                                                               e  4 0.0                                                                               e  4 284.6                                                                             a-d                                                                               4 1.591                                                                             e-f                                                                               4 0.31                                                                              i-j                                                                               4 0.63                                                                              g-h                         __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 61                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                Lesion Scores                                     Treatment                                                                            % Mort.(3)                                                                            Wt. Gain(4)                                                                            Feed/Gain(5)                                                                           Intestinal                                                                            Cecal                                      PPM   # Mean # Mean  # Mean  # Mean # Mean                                     __________________________________________________________________________     NNC                                                                            0     3 0.0                                                                               a 3 280.7                                                                             a  2 1.452                                                                             b  3 0.00                                                                              d 3 0.00                                                                              e                                     IC                                                                             0     3 0.0                                                                               a 3 239.2                                                                             a-b                                                                               3 1.691                                                                             a-b                                                                               3 8.00                                                                              a 3 2.92                                                                              a-b                                   A204                                                                           2     3 8.3                                                                               1 3 261.3                                                                             a-b                                                                               2 1.662                                                                             a-b                                                                               3 6.75                                                                              a 3 3.08                                                                              a-b                                   4     3 0.0                                                                               a 3 235.1                                                                             a-b                                                                               3 1.621                                                                             a-b                                                                               3 5.00                                                                              b 3 3.42                                                                              a                                     8     3 0.0                                                                               a 3 253.1                                                                             a-b                                                                               2 1.456                                                                             b  3 1.00                                                                              d 3 2.00                                                                              a-d                                   Example No. 22                                                                 2     3 8.3                                                                               a 3 258.2                                                                             a-b                                                                               2 1.577                                                                             a-b                                                                               3 3.00                                                                              c 3 2.92                                                                              a-b                                   4     3 0.0                                                                               a 3 261.8                                                                             a-b                                                                               3 1.590                                                                             a-b                                                                               3 0.00                                                                              d 3 2.17                                                                              a-c                                   8     3 0.0                                                                               a 3 171.2                                                                             c  1 1.860                                                                             a-b                                                                               3 0.00                                                                              d 3 0.50                                                                              d-e                                   A204 + Example No. 22                                                          2 + 2 3 0.0                                                                               a 3 279.2                                                                             a  1 1.518                                                                             a-b                                                                               3 0.28                                                                              d 3 2.81                                                                              a-b                                   2 + 4 3 0.0                                                                               a 3 253.2                                                                             a-b                                                                               3 1.577                                                                             a-b                                                                               3 0.00                                                                              d 3 0.83                                                                              c-e                                   2 + 8 3 0.0                                                                               a 3 169.2                                                                             c  2 1.798                                                                             a-b                                                                               3 0.00                                                                              d 3 0.25                                                                              e                                     4 + 2 3 0.0                                                                               a 3 289.3                                                                             a  3 1.459                                                                             b  3 0.08                                                                              d 3 2.25                                                                              a-c                                   4 + 4 3 0.0                                                                               a 3 256.3                                                                             a-b                                                                               2 1.558                                                                             a-b                                                                               3 0.00                                                                              d 3 1.58                                                                              b-e                                   4 + 8 3 0.0                                                                               a 3 217.2                                                                             a-c        3 0.00                                                                              d 3 0.44                                                                              d-e                                   8 + 2 3 0.0                                                                               a 3 284.0                                                                             a  2 1.451                                                                             b  3 0.00                                                                              d 3 0.89                                                                              c-e                                   8 + 4 3 0.0                                                                               a 3 255.6                                                                             a-b                                                                               1 1.587                                                                             a-b                                                                               3 0.00                                                                              d 3 0.08                                                                              e                                     8 + 8 3 0.0                                                                               a 3 195.9                                                                             b-c                                                                               1 2.069                                                                             a  3 0.00                                                                              d 3 0.00                                                                              e                                     __________________________________________________________________________

    __________________________________________________________________________     EXPERIMENT NO. 62                                                              Statistical Analyses of Percent Mortality, Weight Gain, Feed/Gain,             Intestinal and Cecal Lesion Scores of broiler cockerels inoculated with        E. acervulina and E. tenella                                                                                Lesion Scores                                     Treatment                                                                            % Mort.(3)                                                                            Wt. Gain(4)                                                                            Feed/Gain(5)                                                                           Intestinal                                                                             Cecal                                     PPM   # Total %                                                                             # % DTC # Mean  # Mean  # Mean                                    __________________________________________________________________________     NNC                                                                            0     3 0.0                                                                               a 3 320.1                                                                             a  3 1.454                                                                             b  3 0.00                                                                              d  3 0.00                                                                              c                                    IC                                                                             0     3 0.0                                                                               a 3 277.3                                                                             c  3 1.787                                                                             a  3 8.08                                                                              a  3 3.42                                                                              a                                    A204                                                                           2     3 0.0                                                                               a 3 239.3                                                                             b-c                                                                               3 1.787                                                                             a  3 6.33                                                                              b  3 3.42                                                                              a                                    4     3 8.3                                                                               a 3 263.5                                                                             a-c                                                                               2 1.708                                                                             a-b                                                                               3 3.33                                                                              c  3 3.08                                                                              a                                    8     3 0.0                                                                               a 3 272.4                                                                             a-c                                                                               3 1.619                                                                             a-b                                                                               3 0.58                                                                              d  3 3.33                                                                              a                                    Example No. 57                                                                 2     3 16.7                                                                              a 3 238.8                                                                             b-c                                                                               2 1.675                                                                             a-b                                                                               3 5.33                                                                              b  3 3.33                                                                              a                                    4     3 0.0                                                                               a 3 236.3                                                                             b-c                                                                               3 1.748                                                                             a  3 2.83                                                                              c-d                                                                               3 3.00                                                                              a                                    8     3 0.0                                                                               a 3 241.1                                                                             b-c                                                                               2 1.735                                                                             a-b                                                                               3 0.17                                                                              d  3 3.19                                                                              a                                    A204 + Example No. 57                                                          2 + 2 3 0.0                                                                               a 3 268.6                                                                             a-c                                                                               3 1.610                                                                             a-b                                                                               3 2.58                                                                              c-d                                                                               3 3.00                                                                              a                                    2 + 4 3 0.0                                                                               a 3 278.4                                                                             a-c                                                                               3 1.599                                                                             a-b                                                                               3 0.25                                                                              d  3 3.08                                                                              a                                    2 + 8 3 0.0                                                                               a 3 253.9                                                                             a-c                                                                               2 1.691                                                                             a-b                                                                               3 0.00                                                                              d  3 0.97                                                                              b-c                                  4 + 2 3 0.0                                                                               a 3 256.4                                                                             a-c                                                                               3 1.624                                                                             a-b                                                                               3 0.33                                                                              d  3 3.25                                                                              a                                    4 + 4 3 0.0                                                                               a 3 290.0                                                                             a-c                                                                               3 1.543                                                                             a-b                                                                               3 0.00                                                                              d  3 2.08                                                                              a-b                                  4 + 8 3 0.0                                                                               a 3 237.9                                                                             b-c                                                                               3 1.675                                                                             a-b                                                                               3 0.00                                                                              d  3 0.75                                                                              b-c                                  8 + 2 3 0.0                                                                               a 3 290.0                                                                             a-c                                                                               2 1.484                                                                             a-b                                                                               3 0.00                                                                              d  3 1.50                                                                              b-c                                  8 + 4 3 0.0                                                                               a 3 304.3                                                                             a-b                                                                               3 1.497                                                                             a-b                                                                               3 0.00                                                                              d  3 0.58                                                                              c                                    8 + 8 3 0.0                                                                               a 3 265.8                                                                             a-c                                                                               3 1.646                                                                             a-b                                                                               3 0.00                                                                              d  3 0.33                                                                              c                                    __________________________________________________________________________ 

I claim:
 1. A method of controlling coccidiosis in a fowl which comprises administering to the fowl both a first substance and a second substance, said first substance being a polyether antibiotic and said second substance selected from the group consisting of compounds of the formula ##STR3## wherein R¹ represents bromo or chloro,m represents an integer of 0 or 1 and n represents an integer of from 0 to 3, with the sum of m and n being an integer of from 1 to 3; R⁴ represents H, OH, OCH₃, or a group hydrolyzable to a foregoing R⁴ moiety; and R⁵ represents difluoromethyl, chlorodifluoromethyl, 1,1,2,2-tetrafluoroethyl, or a perfluoroalkyl of C₁ -C₃ ; and the physiologically acceptable salts thereof; said first and second substances being administered in amounts which, together, are effective to control coccidiosis in the fowl.
 2. The method of claim 1 wherein the second substance is 1-hydroxy-4-nitro-6-(trifluoromethyl)-2-(1,1,2,2-tetrafluoroethyl)benzimidazole or a physiologically acceptable salt thereof.
 3. The method of claim 2 wherein the first substance is a polyether selected from the group consisting ofantibiotic A204, portmicin, antibiotic A82810, maduramicin, and semduramicin.
 4. The method of claim 3 wherein the polyether is portmicin.
 5. The method of claim 3 wherein the polyether is antibiotic A82810.
 6. The method of claim 1 wherein the second substance is 4-nitro-6-(trifluoromethyl)-2-(1,1,2,2-tetrafluoroethyl)benzimidazole or a physiologically acceptable salt thereof.
 7. The method of claim 6 wherein the first substance is a polyether selected from the group consisting ofantibiotic A204, portmicin, antibiotic A82810, maduramicin, and semduramicin.
 8. The method of claim 7 wherein the polyether is portmicin.
 9. The method of claim 7 wherein the polyether is antibiotic A82810.
 10. The method of claim 1 wherein the second substance is 4-nitro-2,6-bis(trifluoromethyl)benzimidazole or a physiologically acceptable salt thereof.
 11. The method of claim 10 wherein the first substance is a polyether selected from the group consisting ofantibiotic A204, portmicin, antibiotic A82810, maduramicin, and semduramicin.
 12. The method of claim 11 wherein the polyether is portmicin.
 13. The method of claim 11 wherein the polyether is antibiotic A82810.
 14. The method of claim 1 wherein the second substance is 4-nitro-6-(trifluoromethyl)-2-(chlorodifluoromethyl)benzimidazole or a physiologically acceptable salt thereof.
 15. The method of claim 14 wherein the first substance is a polyether selected from the group consisting ofantibiotic A204, portmicin, antibiotic A82810, maduramicin, and semduramicin.
 16. The method of claim 15 wherein the polyether is portmicin.
 17. The method of claim 15 wherein the polyether is antibiotic A82810.
 18. The method of claim 1 wherein the second substance is 4-nitro-2,6-bis(trifluoromethyl)-7-chlorobenzimidazole or a physiologically acceptable salt thereof.
 19. The method of claim 18 wherein the first substance is a polyether selected from the group consisting ofantibiotic A204, portmicin, antibiotic A82810, maduramicin, and semduramicin.
 20. The method of claim 19 wherein the polyether is portmicin.
 21. The method of claim 19 wherein the polyether is antibiotic A82810.
 22. The method of claim 1 where the coccidiosis is attributable to a polyether-insensitive strain of Eimeria.
 23. The method of claim 22 wherein the second substance is 1-hydroxy-4-nitro-6-(trifluoromethyl)-2-(1,1,2,2-tetrafluoroethyl)benzimidazole or a physiologically acceptable salt thereof.
 24. The method of claim 22 wherein the second substance is 4-nitro-6-(trifluoromethyl)-2-(1,1,2,2-tetrafluoroethyl)benzimidazole or a physiologically acceptable salt thereof.
 25. The method of claim 24 wherein the first substance is a polyether selected from the group consisting ofantibiotic A204, portmicin, antibiotic A82810, maduramicin, and semduramicin.
 26. The method of claim 25 wherein the polyether is portmicin.
 27. The method of claim 25 wherein the polyether is antibiotic A82810.
 28. The method of claim 22 wherein the second substance is 4-nitro-6-bis(trifluoromethyl)benzimidazole or a physiologically acceptable salt thereof.
 29. The method of claim 28 wherein the polyether is selected from the group consisting ofantibiotic A204, portmicin, antibiotic A82810, maduramicin, and semduramicin.
 30. The method of claim 29 wherein the polyether is portmicin.
 31. The method of claim 29 wherein the polyether is antibiotic A82810.
 32. The method of claim 22 wherein the second substance is 4-nitro-6-(trifluoromethyl)-2-(chlorodifluoromethyl)benzimidazole or a physiologically acceptable salt thereof.
 33. The method of claim 32 wherein the polyether is selected from the group consisting ofantibiotic A204, portmicin, antibiotic A82810, maduramicin, and semduramicin.
 34. The method of claim 33 wherein the polyether is portmicin.
 35. The method of claim 33 wherein the polyether is antibiotic A82810.
 36. The method of claim 22 wherein the second substance is 4-nitro-2,6-bis(trifluoromethyl)-7-chlorobenzimidazole or a physiologically acceptable salt thereof.
 37. The method of claim 36 wherein the polyether is selected from the group consisting ofantibiotic A204, portmicin, antibiotic A82810, maduramicin, and semduramicin.
 38. The method of claim 37 wherein the polyether is portmicin.
 39. The method of claim 37 wherein the polyether is antibiotic A82810. 